Specifikationer
- Antibody type:Primary
- Antigen symbol:C4d-A
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human
- Form:liquid
- Antigen synonyms:CO4A_HUMAN|C4A|CH|Acidic complement C4|C4A2|CPAMD2|C4A4|C4d-A|CO4B_HUMAN|C4A3|RG.|C4AD|C4S|C4A6|complement C4-A proprotein|C4|RG|CO4|Complement component 4A|Rodgers blood group|Chido blood group|Basic complement C4|Complement component 4B
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
- Concentration:1 ug/ul
- Shipping temperature:4 °C
- Purification:Purified by Protein A.
- Size:100 μg
- Pk:100 µl
Specifikationer
Om denna produkt
This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Type: Primary
Antigen: C4d-A
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Human