- Antibody type:Primary
- Antigen name:EDR1/PHC1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Epitope:751-900/1004
- Form:Liquid
- Gene ID:1911
- Antigen synonyms:Rae28|PH1|Polyhomeotic-like protein 1|PHC1_HUMAN|Early development regulatory protein 1|EDR1 PH1|hPH1|mPH1
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:105 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human EDR1/PHC1
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
PHC1 is a 1004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Existing as a homodimer, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain. PHC1 is encoded by a gene located on human chromosome 12, which encodes over 1100 genes and comprises approximately 4.5% of the human genome.
Type: Primary
Antigen: EDR1/PHC1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 751-900/1004
Host: Rabbit
Isotype: IgG
Reactivity:
: VWR Collection
: EPPENDORF
: EPPENDORF
: VWR Collection
: VWR Collection
: VWR Collection
: EPPENDORF
: VWR Collection
: VWR Collection
: VWR Collection
: VWR Collection
: VWR Collection