42864 Results for: "ProSci Inc."

Supplier: ProSci Inc.

Anti-S Recombinant Antibody [Clone: Sb#45]

Supplier: ProSci Inc.

Anti-S Recombinant Antibody [Clone: Sb#45]

Supplier: ProSci Inc.

Survivin, also called BIRC5, is a protein encoded by the human BIRC5 gene. It is a member of the IAP (inhibitor of apoptosis family. Survivin binds to the active form of Caspase-3 and -7, effector or executioner caspases, preventing them from continuing the apoptosis-signaling cascade. Expression is regulated by p53, a regulator of apoptosis-control genes which interacts with the Survivin gene promoter region to repress its expression at the mRNA and protein level.

Supplier: ProSci Inc.

Krueppel-like factor family members are involved in growth regulation and a wide range of developmental processes. KLF4 is highly expressed in epithelial tissues including skin and stomach/intestine. Studies have shown that KLF4 can function as both an oncogene, upregulating hSSC, and a tumor suppressor, down-regulating colorectal cancer. KLF4 is involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.

Supplier: ProSci Inc.

NAD(P)H:quinone oxidoreductase is an enzyme that catalyses the two-electron reduction of quinones to hydroquinones, resulting in the activation or deactivation of the hydroquinone. Increased expression of NQO1 is seen in tumors of the breast, liver and colon and NSCLC or ‘non-small cell lung cancer,’ suggesting a role in tumor development and possibly treatment. NQO1 has also been linked to Alzheimer's disease, found to be upregulated in response to the oxidative stress of the AD process.

Supplier: ProSci Inc.

Anti-ITGB2 Recombinant Antibody [Clone: 60.3]

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

The TL2.1 monoclonal antibody specifically reacts with human CD282, the Toll-like receptor 2 (TLR2). It is a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain. CD282 is expressed on peripheral blood monocytes and is involved distinguishing bacterial lipoproteins. The TL2.1 antibody blocks the receptor and immunoprecipitates TLR2 from human mammary epithelial cells (HMEC) and peripheral blood mononuclear cells (PBMC).

Supplier: ProSci Inc.

The TL2.1 monoclonal antibody specifically reacts with human CD282, the Toll-like receptor 2 (TLR2). It is a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain. CD282 is expressed on peripheral blood monocytes and is involved distinguishing bacterial lipoproteins. The TL2.1 antibody blocks the receptor and immunoprecipitates TLR2 from human mammary epithelial cells (HMEC) and peripheral blood mononuclear cells (PBMC).

Supplier: ProSci Inc.

The TER-119 monoclonal antibody specifically binds to the mouse 52 kDa Glycophorin A expressed on the erythroid lineage cells, from the early proerythroblast to mature erythrocyte stages, in the fetal liver, adult bone marrow, newborn liver, yolk sac, and adult lymphoid organs. The TER-119 antibody is used, together with other antibodies, as a marker for hematopoietic lineages cells.

Supplier: ProSci Inc.

The 11B11 monoclonal antibody specifically reacts with mouse 14 kDa cytokine IL-4, expressed by the activated NKT cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen.The 11B11 antibody neutralizes the IL-4 cytokine.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

Anti-TM9SF3 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-HAUS8 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-CALML5 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-ALDH9A1 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-INPP5K Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-SPICE1 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000. For IF starting dilution is: 1:10~50.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

The RB6-8C5 monoclonal antibody reacts with the mouse Ly-6G (also known as Gr-1). The Ly-6G protein is a myeloid differentiation antigen of 21 to 25 kDa, expressed in a regulated manner by the myeloid lineage in the bone marrow, where the level of antigen expression is correlated with the granulocyte maturation and differentiation. In the bone marrow, the antigen is not expressed by the erythroid cells. From the peripheric cells, RB6-8C5 binds with monocytes, neutrophils and eosinophils.As a marker for the mouse monocytes, macrophages and granulocytes, the RB6-8C5 antibody is usually combined with M1/70, a macrophage labeling antibody (Anti-CD11b), for phenotypic analysis.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.