Supplier: ProSci Inc.

Anti-SIRT6 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-PDCD2L Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-CAMK1G Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-PRDM5 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

G protein receptors, also called GPRs, GPCRs, and seven-transmembrane domain receptors, are a large family of receptors with possibly over 800 members. These receptors sense stimuli outside, convey the signal across the cell membrane, and activate internal signal transduction pathways and cellular responses. GPR77 is involved in the complement system of the innate immune response and may signal through the beta-arrestin pathway, and possibly act as a decoy receptor. It is co-expressed with the C5a receptor on neutrophils and may modulate C5a1 activity.

Supplier: ProSci Inc.

This antibody recognises an oncofetal glycoprotein with a single chain of 70 kDa, which is identified as Alpha fetoprotein (AFP). The AFP antibody is highly specific and shows no cross-reaction with other oncofetal antigens or serum albumin. Alpha fetoprotein is normally synthesised in the liver, intestinal tract, and yolk sac of the fetus. AFP antibody has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

Supplier: ProSci Inc.

Part of the innate immune response to infection is the production of type I IFNs (interferons). The murine Ifi200 family of proteins are activated by IFNs. IFI204 (Interferon-activable protein 204), or p204, is a regulator of bone production and the differentiation of macrophages and skeletal and cardiac muscle cells.

Supplier: ProSci Inc.

Autophagy is the cellular mechanism of degradation and turnover of unnecessary or dysfunctional cellular components. The unneeded components are engulfed in vesicles called autophagosomes, where they are broken down and recycled. The ‘autophagy-related gene’ ATG4B is a regulator of autophagasome maturation. The microtubule-associated protein LC3-I is lipidated (called LC3-II in its lipidated state) and recruited to the autophagosomal membrane where it is of vital importance in the maturation of autophagosomes. ATG4B regulates LC3-II availability by modulating LC3-I lipidation.

Supplier: ProSci Inc.

The Runt family of transcription factors is involved in both normal cell development and carcinogenesis. Runt-related transcription factor 3 has been shown to be a tumor suppressor. Hypermethylation and mislocalization of the protein to the cytoplasm leads to low levels of RUNX3 and increased proliferation of breast and gastric tumor cells.

Supplier: ProSci Inc.

RUNX (runt-related transcription factor) proteins are a family of transcription factors involved in many different biological systems, including cell differentiation and cancer. RUNX2 is an essential factor in bone development, acting as a scaffold protein for nucleic acids and regulatory factors involved in skeletal gene expression. It is also involved in cancer cell movement, activating factors involved in the metastasis of prostate and breast cancer cells to bone.

Supplier: ProSci Inc.

This antibody recognises a 67 kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. antibody to CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. CD5 antibody detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. CD5 antibody is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, antibody to CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). CD5 antibody does not react with granulocytes or monocytes.

Supplier: ProSci Inc.

Anti-NFYB Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-TWIST1 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-CAPG Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-RUNX3 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-GRM4 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-SGTA Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-PAX6 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-ETS2 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-ZNF195 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

The 2F1 monoclonal antibody is specific for the mouse Killer cell Lectin-like Receptor G1 (KLRG1), a homodimer consisting of two N-glycosylated subunits of 30-38 kDa, also known as MAFA (Mast cell Function-associated Antigen). The antigen contains a cytoplasmic motif similar to ITIM (the immunoreceptor tyrosine-based inhibitory motif). KLRG1 is a receptor for cadherin, a family of transmembrane glycoproteins that mediate cell adhesion, and a common marker of T cell senescence. The receptor is believed to play an important role in the innate and adaptive immune system through the regulation of leukocytes. It is expressed on lymphokine-activated killer (LAK) cells, adherent LAK (A-LAK) cells, a sub-set of natural killer (NK) cells, T cells. In NK cells, it inhibits cytokine production and cytotoxicity activity.The receptor expression was not detected on the mouse peritoneal mast cells, or bone marrow mast cells.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

Anti-MYC Recombinant Antibody [Clone: 9E10]

Supplier: ProSci Inc.

Anti-Fluorescein (FITC) Recombinant Antibody [Clone: 4-4-20 (enhanced)]

Supplier: ProSci Inc.

Anti-His tag Recombinant Antibody [Clone: 3D5]

Supplier: ProSci Inc.

Anti-His tag Recombinant Antibody [Clone: 3D5]

Supplier: ProSci Inc.

Anti-MYC Recombinant Antibody [Clone: 9E10]

Supplier: ProSci Inc.

Anti-His tag Recombinant Antibody [Clone: 3D5]