42864 Results for: "ProSci Inc."

The TS2/16 moncolonal antibody specifically reacts with human CD29 (Integrin beta1), a 130 kDa type I glycoprotein expressed on hematopoietic and non-hematopoietic cells. It forms the VLA-(1-6) molecules with integrin alpha-(1-6) and is involved in the adhesion between cell-cell and cell-matrix. The TS2/16 antibody has been found to activate beta 1 integrins.

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Anti-TREML1 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

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Anti-Fxyd1 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

This gene encodes a member of the FXYD family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity and act as an accessory protein of Na,K-ATPase. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.

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Anti-GPR142 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

GPR142 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).

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Anti-KRT25 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21.

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Anti-ENG Mouse Monoclonal Antibody [clone: SN6] (PE (Phycoerythrin))

Supplier: ProSci Inc.

The SN6 monoclonal antibody specifically reacts with human CD105 (Endoglin), a 90 kDa homodimeric glycoprotein expressed on vascular endothelial cells, activated macrophages, and a subset of bone marrow cells. CD105 is a marker for tumor angiogenesis research by identifying proliferating endothelium. It is also suggested to be involved in embryonic angiogenesis and cellular adhesion.

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Anti-KATNA1 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

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Anti-LRRC14B Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

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Anti-CUX1 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

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Anti-CLCF1 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

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Anti-ENG Mouse Monoclonal Antibody [clone: STA] (PE (Phycoerythrin))

Supplier: ProSci Inc.

The STA monoclonal antibody specifically reacts with human CD106, a 110 kDa glycoprotein also named Vascular Cell Adhesion Molecule-1 (VCAM-1) and INCAM-110. Its expression is induced by inflammation stimuli and cytokines and it is found mainly on activated vascular endothelium. CD106 is also found on subsets of macrophages, stromal cells, dendritic cells, and myeloid lineage cells. The integrins that bind CD106 are CD49d/CD29 and LPAM-1, and it is involved in cell adhesion, transmigration and T cell proliferation.

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Anti-Kit Rat Monoclonal Antibody [clone: ACK2] (PE (Phycoerythrin))

Supplier: ProSci Inc.

The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene. The c-Kit receptor, also known as stem cell factor receptor, is expressed on hematopoietic progenitor cells in adult bone marrow, in progenitors of erythroid and myeloid lineages, and precursors of B and T cells. CD117 enhances the proliferation and the differentiation of the hematopoietic progenitor cells and seems to enhance the development of T cells, as the c-Kit receptor and its ligand are expressed by the thymus.