5269 Results for: "Enzo Life Sciences"
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Protease Inhibitor I aldehyde
Supplier: Enzo Life Sciences
Cell permeable inhibitor of the 26S proteasome (MCP; multicatalytic proteinase complex) in HT4 cells. Causes accumulation of ubiquitinylated proteins in neuronal cells. Prevents the activation of NF-κB in response to TNF-α or okadaic acid through inhibition of IκBα degradation.
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Ophiobolin A
Supplier: Enzo Life Sciences
Calmodulin antagonist. PDE inhibitor.
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bpV(HOpic) ≥90% (by 51V-NMR)
Supplier: Enzo Life Sciences
PTP inhibitor, PTEN Inhibitor
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Purvalanol A ≥99% (by NMR)
Supplier: Enzo Life Sciences
Inhibitor of human CDK1 (IC50=4nM), CDK2/cyclin A (IC50=70nM), Cdc2/cyclin B, CDK2/cyclin E (IC50=35nM), CDK4/cyclin D1 (IC50=850nM) as well as CDK5/p35 (IC50=75nM). More membrane permeable than purvalanol B.
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4-Phenylchalcone oxide (synthetic) ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Potent and selective inhibitor of microsomal and cytosolic epoxide hydrolase (IC50=68 nM). Inhibits epoxide hydrolysis of epoxyeicosatrienoic acids.
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2-(4-Isobutylphenyl)propanoic acid ≥99%
Supplier: Enzo Life Sciences
COX inhibitor
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Cytidine-5'-diphosphocholine sodium salt (CDP choline) ≥99%
Supplier: Enzo Life Sciences
Completely inhibits PLA2 activation following cryogenic brain injury in the rabbit at 200 mg/kg. Intermediate in phospholipid biosynthesis.
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RG-13022 ≥98% (by TLC)
Supplier: Enzo Life Sciences
RG-13022 is a non-phenolic tyrphostin analog, which inhibits the EGF receptor (IC50=5 µM) and PDGF receptor tyrosine kinases, and is long-acting. It inhibits EGF-stimulated HER14 cell proliferation (IC50=1 µM) as well as tumor growth in vivo. It inhibits both EGF- and PDGF-stimulated DNA synthesis in human glioma cell lines. RG-13022 is non-phenolic and therefore possesses less antioxidant activity than other tyrphostins.
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Tyrphostin AG 183 ≥99%
Supplier: Enzo Life Sciences
A potent inhibitor of EGF receptor kinase activity (IC50=0.8 µM). Inhibition is mixed competitive with ATP and substrate.
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Benzylphosphonic acid-(AM)2 ≥98% (by TLC)
Supplier: Enzo Life Sciences
Benzylphosphonic acid-(AM)2 is a bis-acetoxymethyl ester (AM) derivative of benzylphosphonic acid which is cell permeable and is converted to the active phosphonic acid via intracellular esterase-catalyzed cleavage of the AM esters.
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Bisindolylmaleimide I ≥98% (by TLC)
Supplier: Enzo Life Sciences
Potent and selective protein kinase C inhibitor which has been used effectively in platelets, Swiss 3T3 fibroblasts and macrophages. Inhibitory profile: PKC, IC50=0.02µM (inhibits α, ßI, ßII and γ subtypes with similar potency); PKA, IC50=2.0µM; phosphorylase kinase, IC50=0.7µM; insulin, EGF and PDGF receptor tyrosine kinases are not inhibited at concentrations up to 50µM.
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Rufloxacin ≥98%
Supplier: Enzo Life Sciences
Fluoroquinolone antibacterial agent. Structurally similar to ofloxacin (Prod. No. ALX-380-297). Specific inhibitor of bacterial DNA gyrase (topoisomerase). Inhibits B-cell differentiation. Shows photosensitizing effects.
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Vancomycin hydrochloride (from Streptomyces lysosup)
Supplier: Enzo Life Sciences
Glycopeptide antibiotic. Interferes with cell wall synthesis. Effective against Gram-positive bacteria.
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Monastrol ≥98% (by TLC)
Supplier: Enzo Life Sciences
Cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC50=14µM) by binding to the mitotic kinesin Eg5.
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: GRANT INSTRUMENTS
: BOCHEM
: VWR Collection
: DWK Life Sciences
: Thermo Fisher Scientific
: VWR Collection
: Oxford Nanopore Technologies
: Industrial Physics
: AAT BIOQUEST
: Integra
: Palbam
: VWR Collection
: Integra
: VWR Collection
: FACELLITATE
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: Greiner Bio-One