5268 Results for: "ENZO LIFE SCIENCES"

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This peptide, EFGTYGTLSKKK, is derived from a peptide (pF4) discovered, through phage display, to be a very good substrate for Fyn kinase.

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DnaK possesses an autophosphorylation activity and a weak 5-nucleotidase activity, cleaving the 5 phosphate groups from both ribose and deoxyribose nucleotides. The role of DnaK in ATP-dependent protein-protein interactions has been extended to normal E. coli physiology, where, like eukaryotic Hsp70 homologs, it is thought to participate in the assembly/disassembly of protein complexes.

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Methotrexate

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n-Dodecyl-β-D-maltoside

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Circulating metabolite of PGE1 in man. Vasodilator equipotent with PGE12. Inhibits human platelet aggregation. Antimitotic activity.

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Blocks actin filament assembly

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Inhibitor of cAMP-dependent protein kinase (PKA), preferentially binding to type I PKA. Lipophilic analog of Rp-cAMPS. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic and membrane permeant as compared to Rp-cAMPS or 8-Br-cAMP.

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Substrate for caspase-1 and -4

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For the quantitative determination of mouse IL-4 in culture supernatants and serum. Cited sample type includes plasma.

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The lymphocyte activation gene-3 (LAG-3, CD223), a member of the immunoglobulin superfamily (IgSF) related to CD4, binds to the major histocompatibility complex (MHC) class II molecules but with higher affinity than CD4. Several alternative mRNA splice-variants of human LAG-3 have been described, two of them encoding potential secreted forms: LAG-3V1 (i.e. the D1-D2 domains of the protein, 36 kDa) and LAG-3V3 (D1-D3, 52 kDa). The longer form was detected by ELISA in the serum of healthy individuals as well as of tuberculosis patients with a favorable outcome. LAG-3 expression by T cell clones correlated with IFN-γ production, and hence soluble LAG-3 has been suggested as a serological marker of Th1 responses.

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Serotonin receptor ligand.

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beta-Amyloid (1-40)

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PPAR ligand.

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Inhibitor of PDK1, TBK1, IKK-ε, IRF3

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Activator for TLR3 and MDA5.

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PKC inhibitor

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Prevents neurotoxicity of glutamate on neuronal cells.

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Produced in E.coli.

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Highly sensitive LH ELISA kit enabling detection of LH in serum, plasma and tissue culture media in just 2 hours.

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Osteopontin (OPN) is an acidic extracellular matrix cell adhesion protein that is relatively abundant not only in bone matrix, plasma, urine, and milk, but is also found in malignant and atherogenic tissues. Phosphorylation, glycosylation and calcium modifications allow intact and fragmented Osteopontin to direct a variety of diverse responses including tissue remodeling, inflammation and cell survival. Plasma Osteopontin has been shown to provide prognostic information in breast, prostate, colon, and lung cancers as well as metastatic carcinomas. The notable presence of Osteopontin in a variety of tumors is strongly correlated to pathological stage, suggesting its critical role in tumor invasiveness, progression and metastasis. In addition, Osteopontin inhibits inducible nitric oxide synthase activity, thereby protecting tumor cells from NO-mediated macrophage cytotoxic attack. Osteopontin is found in atherosclerotic plaques and may drive a number of diabetic vascular pathologies.

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Cofactor of nitric oxide synthases (NOS).

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Produced in E. coli.

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Potentiates PKC activity

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The adrenergic ligand library contains 84 ligands including endogenous neurotransmitters, agonists, antagonists, and marketed drugs. The library is ideal for screening or identifying recombinant orphan G protein-coupled receptors, target validation, secondary screening, assay development, and other pharmacological applications. The adrenergic ligand library is 1 plate of the larger neurotransmitter library which contains over 650 CNS receptor ligands.

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For the detection of apoptotic cells by flow cytometry.

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Potent and selective serotonin uptake inhibitor

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Anti-PARP1 Mouse Monoclonal Antibody [clone: C-2-10]

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APRIL (A proliferation-inducing ligand) is a member of the TNF family. APRIL stimulates B- and T-cell proliferation, triggers humoral immune responses, activates NF-κB, and induces cell death.

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TLR4 activator.

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The ROS-ID® Hypoxia/Oxidative Stress Detection Kit is a specific detection system designed for functional detection of hypoxia and oxidative stress levels in live cells (both suspension and adherent) using fluorescent microscopy or flow cytometry.