5269 Results for: "ENZO LIFE SCIENCES"
Olomoucine ≥98%, high purity
Supplier: ENZO LIFE SCIENCES
Olomoucine is a purine derivative which acts as a potent and selective inhibitor of CDK1 (p34cdc2)/cyclin B and related kinases. It acts by competing for the ATP binding domain of the kinase. Of 35 protein kinases tested, olomoucine inhibited p33CDK2/cyclin A, p33CDK2/cyclin E, p34cdc2/cyclin B, p33CDK5/p35 and erk1 with IC50 of 7, 7, 7, 3 and 25µM respectively. The related kinases p34CDK4/cyclin D and p40CDK6/cyclin D3 were not inhibited or were less sensitive to olomoucine, IC50 > 1000 and 250µM respectively. PKC, PKA, PKG, CaM kinase II, MLC kinase, CK2, EGFR tyrosine kinase, p56lck, p56lyn, p60c-src, v-abl and insulin receptor tyrosine kinase are not inhibited or are weakly inhibited at 1mM. It delays mouse oocyte maturation and inhibits the growth of a variety of human cell lines including Rhabdomyosarcoma cell line Rh1, Rh18, Rh28 and Rh30; MCF-7, KB-3-1 and their adriamycin-resistant counterparts (IC50=18-86µM). It inhibits DNA synthesis in interleukin-2-stimulated T lymphocytes and triggers a G1 arrest similar to interleukin-2 deprivation. Can be used to synchronize cells in G1. Triggers apoptosis in target tumor cells in vitro and in vivo and in maturing cerebellar granule neurons. N9-Isopropyl-olomoucine and the negative control Iso-olomoucine are also available.
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Undeca-ubiquitin (linear)
Supplier: ENZO LIFE SCIENCES
Produced in E. coli.
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Why Choose Corning Fetal Bovine Serum?
Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.
Congo red ≥95% (by HPLC), Ultrapure
Supplier: ENZO LIFE SCIENCES
beta-Amyloid dye
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Prostaglandin D₂ ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Prostanoid receptor ligand.
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(+)-cis-Diltiazem hydrochloride ≥99% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Inhibitor of L-type Ca²⁺ channels. Regulates Ca²⁺ release from intracellular stores in neutrophils.
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Anti-INOS Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
Host: Rabbit, Isotype: IgG
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(+)-Himbacine ≥98%, powder
Supplier: ENZO LIFE SCIENCES
Muscarinic acetylcholine receptor antagonist.
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Spermine tetrahydrochloride
Supplier: ENZO LIFE SCIENCES
Spermine tetrahydrochloride
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PTIO (=2-phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) ≥98% (by non aqueous titration)
Supplier: ENZO LIFE SCIENCES
Stable nitric oxide (NO) radical scavenger.
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3,5,7,4'-Tetrahydroxy-3'-methoxyflavone ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Antitumor agent.
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4-Phenylchalcone oxide (synthetic) ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Potent and selective inhibitor of microsomal and cytosolic epoxide hydrolase (IC50=68 nM). Inhibits epoxide hydrolysis of epoxyeicosatrienoic acids.
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1-Acetoxy-3-carbamoyl-2,2,5,5-tetramethylpyrrolidine (ACP)
Supplier: ENZO LIFE SCIENCES
Cell permeable probe for the detection of intracellular oxidative stress.
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Retinoic acid all trans ≥95%, yellow solid
Supplier: ENZO LIFE SCIENCES
Retinoic acid receptor ligand
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Anti-INOS Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
Host: Rabbit
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Bisindolylmaleimide I ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Potent and selective protein kinase C inhibitor which has been used effectively in platelets, Swiss 3T3 fibroblasts and macrophages. Inhibitory profile: PKC, IC50=0.02µM (inhibits α, ßI, ßII and γ subtypes with similar potency); PKA, IC50=2.0µM; phosphorylase kinase, IC50=0.7µM; insulin, EGF and PDGF receptor tyrosine kinases are not inhibited at concentrations up to 50µM.
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JK 184 ≥99% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Hedgehog (Hh) pathway blocker.
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Hypoxia/oxidative stress detection kit, ROS-ID®
Supplier: ENZO LIFE SCIENCES
The ROS-ID® Hypoxia/Oxidative Stress Detection Kit is a specific detection system designed for functional detection of hypoxia and oxidative stress levels in live cells (both suspension and adherent) using fluorescent microscopy or flow cytometry.
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LTB4 ELISA kit
Supplier: ENZO LIFE SCIENCES
For the quantitative determination of LTB4 in culture supernatants, plasma, saliva, and urine from any species. Cited sample types include bronchioalveolar lavage fluid, cell lysate, crevicular fluid, tissue, serum and whole blood.
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L(-)-Glutathione (reduced form)
Supplier: ENZO LIFE SCIENCES
L(-)-Glutathione (reduced form)
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Anti-Tubulin Alpha Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
Host: Rabbit
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Deoxynivalenol (from Fusarium sp.) ≥98% (by HPLC, TLC)
Supplier: ENZO LIFE SCIENCES
Mycotoxin found in cereals. Binds to the ribosome and inhibits protein synthesis.
Emetic and refusal activity in pig.
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Streptozocin ≥97%
Supplier: ENZO LIFE SCIENCES
Widely used diabetes inducer in rodents. Inhibition of β-cell O-GlcNAcase by streptozotocin is the mechanism that accounts for its diabetogenic toxicity. N-nitroso-containing antibiotic, acting as a nitric oxide (NO) donor and vasorelaxant. Relaxes phenylephrine-contracted aortic rings at 10µM. Potent methylating agent for DNA.
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