Supplier: Charles River Laboratories Cell Solutions

Human serum used for researching the causes, diagnosis, supportive care and treatment psoariasis (PSO). Collected from IRB-consented donors diagnosed with PSO.

Supplier: Charles River Laboratories Cell Solutions

Human mononuclear cells, Hepatitis B virus (HBV)

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Human plasma, lung cancer (LC)

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Human mononuclear cells, systemic lupus erythematosus (SLE)

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Human serum used for researching the causes, diagnosis, supportive care and treatment of chronic myeloid leukemia (CML). Collected from IRB-consented donors diagnosed with CML.chronic lymphocytic leukemia (CLL)

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Human plasma, non-Hodgkin’s lymphoma (NHL)

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Human peripheral blood M2 macrophages are derived from purified monocytes. CD14⁺ monocytes were positively selected via immunomagnetic beads and were cultured in the presence of M-CSF for 10 days. The M2 phenotyping was confirmed by morphology and the expression of specific biomarkers which monitored by flow cytometry. The cells were harvested after 10 days of in vitro culture.

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Human mononuclear cells, multiple myeloma

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Human serum, chronic lymphocytic leukemia (CLL)

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CD34⁺ cells are isolated using positive immunomagnetic cell separation procedures from umbilical cord blood. Human cord blood is collected aseptically at the time of delivery from healthy pregnant women under institutional review board (IRB) approved procedures.

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CD34 depleted mononuclear cells from mobilised peripheral blood are isolated by depleting the CD34 cells using immunomagnetic anti-CD34 microbeads.

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Ulcerative colitis (UC) is isolated from mononuclear cells collected from IRB-consented donors diagnosed with ulcerative colitis (UC).

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Bone marrow is a major source of stem cells, which are being used in cancer research, cell studies, transplantation studies, and other research.

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Mesenchymal stem cells (MSC) are cultured from freshly collected adult human bone marrow. MSCs are isolated by adherence from bone marrow mononuclear cells, isolated using a density gradient. Adherent cells were cultured in MEM-alpha, supplemented with L-glutamine and Human Platelet Lysate. Bone marrow aspirate is collected from healthy human volunteer donors under IRB approved informed consent and drawn from the posterior iliac crest using a syringe containing anticoagulant.

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CD56⁺ NK cells are isolated from mononuclear cells either by positive selection using an antibody that targets the CD56 antigen, or by negative selection using immunomagnetic cell separation procedures.

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CD3⁺ T cells are isolated from mononuclear cells by positive selection using immunomagnetic cell separation procedures.

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Neutrophils are derived from a dextran red cell sedimented population of cells. Following red cell sedimentation, granulocytes are separated using a density gradient and red cell lysis. Cells are then purified through the use of indirect selection.

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Mononuclear cells used for researching the causes, diagnosis, supportive care and treatment of chronic myeloid leukemia (CML). Human mononuclear cells are collected from human volunteer donors diagnosed with CML under IRB approved informed consent.

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Serum used for researching the causes, diagnosis, supportive care and treatment of acute myeloid leukemia (AML). Serum is collected from IRB-consented volunteer donors diagnosed with acute myeloid leukemia (AML).

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Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of type 2 diabetes mellitus (DM 2). Collected from IRB-consented donors diagnosed with type 2 diabetes mellitus.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of herpes simplex virus 2 (HSV 2). Collected from IRB-consented donors diagnosed with HSV 2.

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Human serum used for researching the causes, diagnosis, supportive care and treatment of human immunodeficiency virus (HIV). Collected from IRB-consented donors diagnosed with HIV.

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The mononuclear cell is a widely used product in research and clinical applications such as in microbiology, virology, oncology, vaccine development, transplant and regenerative biology, and toxicology.

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Dendritic cells are obtained from a leukapheresis product using immunomagnetic separation techniques.

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Plasma used for researching the causes, diagnosis, supportive care and treatment of ulcerative colitis (UC). Collected from IRB-consented volunteer donors diagnosed with UC.

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Human serum, lung cancer

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Human serum used for researching the causes, diagnosis, supportive care and treatment of multiple sclerosis (MS). Collected from IRB-consented donors diagnosed with MS.

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Mononuclear cells (MNCs) used for researching the causes, diagnosis, supportive care and treatment of Hepatitis C Virus (HCV). Human mononuclear cells are collected from human volunteer donors diagnosed with Hepatitis C virus under IRB approved informed consent.

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Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of chronic myeloid leukemia (CML). Collected from IRB consented chronic myeloid leukemia (CML) disease donors.

Supplier: Charles River Laboratories Cell Solutions

Human plasma, breast cancer (BC)