Anti-CD2 Mouse Monoclonal Antibody [clone: RPA-2.10] (APC)

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD2, APC-conjugated.

T cells

The RPA-2.10 antibody reacts with CD2, an ~50 kDa type I transmembrane glycoprotein and a member of the immunoglobulin (Ig) superfamily; two Ig-like domains are located in its extracellular portion. CD2 is broadly expressed on peripheral T and NK cells, dendritic cells, erythrocytes, most thymic T cells, subsets of thymic B cells, and on the endothelium. CD2 expression appears early during T cell differentiation. Aberrant expression has been observed in some lymphomas and myeloid leukemias. CD2 is critically important for T cell activation and signaling, as well as lymphocyte adhesion. The primary ligand for CD2 is CD58 (LFA-3) located on antigen-presenting cells, with additional ligands comprising CD15 (SSEA-1), CD48 and CD59. Notably, the RPA-2.10 antibody blocks the mixed lymphocyte reaction.

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Type: Anti-CD2 Mouse Monoclonal Antibody [clone: RPA-2.10] (APC)
Antigen: CD2
Clonality: Monoclonal
Clone: RPA-2.10
Conjugation: APC
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Baboon, Capuchin monkey, Chimpanzee, Cynomolgus monkey, Human, Pig, Pigtailed macaque, Rhesus monkey, Squirrel monkey

Catalog No:
STMC60007AZ.1
STMC100-0432
STMC60007AZ

Antigen name:
CD2
CD2
CD2

Clonality:
Monoclonal
Monoclonal
Monoclonal

Conjugation:
APC (Allophycocyanin)
APC (Allophycocyanin)
APC (Allophycocyanin)

Clone:
RPA-2.10
RPA-2.10
RPA-2.10

Reactivity:
Baboon, Capuchin monkey, Pig, Cynomolgus monkey, Rhesus monkey, Pigtailed macaque, Chimpanzee, Human, Squirrel monkey
Baboon, Capuchin monkey, Pig, Cynomolgus monkey, Rhesus monkey, Pigtailed macaque, Chimpanzee, Human, Squirrel monkey
Baboon, Capuchin monkey, Pig, Cynomolgus monkey, Rhesus monkey, Pigtailed macaque, Chimpanzee, Human, Squirrel monkey