Specifications
- Antibody type:Primary
- Antigen name:killer cell lectin-like receptor subfamily G, member 1
- Antigen symbol:Klrg1
- Clonality:Monoclonal
- Clone:2F1
- Conjugation:APC (Allophycocyanin)
- Flow cytometry:Yes
- Host:Hamster
- Isotype:IgG
- Cross adsorption:No
- Form:liquid
- Gene ID:O88713
- Antigen synonyms:Klrg1
- Storage buffer:Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
- Storage temperature:The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
- Shipping temperature:4 °C
- Purification:The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Pk:0,1 mg
Specifications
About this item
The 2F1 monoclonal antibody is specific for the mouse Killer cell Lectin-like Receptor G1 (KLRG1), a homodimer consisting of two N-glycosylated subunits of 30-38 kDa, also known as MAFA (Mast cell Function-associated Antigen). The antigen contains a cytoplasmic motif similar to ITIM (the immunoreceptor tyrosine-based inhibitory motif). KLRG1 is a receptor for cadherin, a family of transmembrane glycoproteins that mediate cell adhesion, and a common marker of T cell senescence. The receptor is believed to play an important role in the innate and adaptive immune system through the regulation of leukocytes. It is expressed on lymphokine-activated killer (LAK) cells, adherent LAK (A-LAK) cells, a sub-set of natural killer (NK) cells, T cells. In NK cells, it inhibits cytokine production and cytotoxicity activity.The receptor expression was not detected on the mouse peritoneal mast cells, or bone marrow mast cells.
Type: Primary
Antigen: Klrg1
Clonality: Monoclonal
Clone: 2F1
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Hamster
Isotype: IgG
Reactivity: Mouse