Methyl-4-hydroxybenzoate 99.0-102.0% (by acidimetry), EMPROVE® ESSENTIAL NF, JP, Ph. Eur., BP, FCC suitable for use as excipient E218, SAFC®
Supplier: MERCK PRODUCTION CHEMICALS
Certificates
About this item
Synonyms: Methylparaben, 4-Hydroxybenzoic acid methyl ester, Methyl Parahydroxybenzoate, Methyl 4-hydroxybenzoate
CAS Number:99-76-3
:
Formula:HOC₆H₄CO₂CH₃
MDL Number:MFCD00002352
:152.15 g/mol
Merck Index:13,06129
Boiling Pt:270…280 °C (1013 hPa)
Melting Pt:125…128 °C
Density:1.1208 g/cm³ (137 °C)
EINECS:202-785-7
:GHS07
Storage Temperature:Ambient
Specifications
- Environmentally Preferable:
Specifications
Specification Test Results
- Assay (Acidimetric):99.0 - 102.0 %
- Assay (HPLC):99.0 - 100.5 %
- Identity:passes test
- Appearance of solution:passes test
- Acidic substances:passes test
- Melting range (lower value):≥ 125 °C
- Melting range (upper value):≤ 128 °C
- Heavy metals (as Pb):≤ 10 ppm
- As (Arsenic):≤ 3 ppm
- Cd (Cadmium):≤ 10 ppm
- Cu (Copper):≤ 10 ppm
- Hg (Mercury):≤ 1 ppm
- Pb (Lead):≤ 2 ppm
- Zn (Zinc):≤ 10 ppm
- Related substances (HPLC):passes test
- p-Hydroxy benzoic acid:≤ 0.5 %
- Sum of all impurities:≤ 1.0 %
- Largest unspecified impurity:≤ 0.5 %
- Methanol (HS-GC):≤ 3000 ppm
- Other residual solvents (ICH Q3C):excluded by manufactoring process
- Sulfated ash:≤ 0.05 %
- Loss on drying (80 °C):≤ 0.5 %
Specification Test Results
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