Human recombinant alpha-Synuclein (from E. coli)
ENZOALX201265C100
:
- Pk:100 µG
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Seq:02
- Protein/peptide name:Alpha-Synuclein
- Purity:>95% (SDS-PAGE)
- Concentration:1 mg/ml
- Formulation:Liquid. In 20 mM TRIS-HCl, pH 7,5, containing 0,1M sodium chloride and 1 mM magnesium dichloride.
Produced in E. coli. alpha-synuclein is a major component of Parkinson's disease aggregates and is implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders.
alpha-synuclein accumulates in the brains of sporadic Parkinson's disease patients as a major component of Lewy bodies, which are intraneuronal cytoplasmic inclusions characteristic of Parkinson's disease.
alpha-synuclein appears to associate with other proteins that aggregate and is found in beta-amyloid plaques and neuritic tangles in Alzheinmer's disease.