Specifications
- Antigen name:Runt-related Transcription Factor 2
- Antigen symbol:RUNX2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- Reactivity:Human,Dog,Rat,Mouse
- Western blot:Yes
- Form:Lyophilized
- Antigen synonyms:Acute myeloid leukemia 3 protein|PEBP2A|CBFA1|PEBP2-alpha A|SL3/AKV core-binding factor alpha A subunit|Polyomavirus enhancer-binding protein 2 alpha A subunit|OSF2|OSF-2|Core-binding factor subunit alpha-1|RUNX2|Runt-related transcription factor 2|PEA2-alpha A|CBF-alpha-1|Osteoblast-specific transcription factor 2|SL3-3 enhancer factor 1 alpha A subunit|AML3|Oncogene AML-3
- Immunogen:A synthetic peptide corresponding a region of human RUNX2.
- Size:100 µg
- Pk:100 µG
Specifications
About this item
The RUNX2 gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).
Antibody is purified by protein A chromatography method.
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type:
Antigen: RUNX2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Dog, Human, Mouse, Rat