Micro extraction by packed sorbent (MEPS™)

Micro Extraction by Packed Sorbent (MEPS™) is a new development in the field of sample preparation by SPE (solid phase extraction). The MEPS™ product consists of two parts, the MEPS™ syringe and the MEPS™ Barrel Insert and Needle assembly (BIN). The MEPS™ approach to sample preparation is suitable for reversed phases, normal phases, mixed mode and ion exchange chemistries. Because MEPS™ BINs can be used for sample volumes as small as 10 µl it makes them particularly well suited to on-line use with LC-MS analysis of volume limited samples.

• The BIN contains the SPE phase that is built into the syringe needle
• The BIN is used with a 100 or 250 µl gas tight MEPS™ syringe that allows fluid handling at normal SPE pressures
• Sample preparation for complex biological samples is readily adapted to MEPS™ and reduces the volume of sample and reagents required for extraction

Base material is silica with mean particle size of 45 µm and pore size of 60 Å.