Streptozocin
Streptozocin
Supplier: Abcam
Selective pancreatic β-cell toxin. DNA alkylating agent. Diabetagen and anticancer activity in vivo.
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Streptozocin ≥95%
Supplier: Apollo Scientific
Usage: Biochemical/ life science applications.
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Streptozocin ≥97%
Supplier: Enzo Life Sciences
Widely used diabetes inducer in rodents. Inhibition of β-cell O-GlcNAcase by streptozotocin is the mechanism that accounts for its diabetogenic toxicity. N-nitroso-containing antibiotic, acting as a nitric oxide (NO) donor and vasorelaxant. Relaxes phenylephrine-contracted aortic rings at 10µM. Potent methylating agent for DNA.
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Streptozocin ≥97% (~75% α-anomer basis), off-white powder
Supplier: MP Biomedicals
Streptozotocin, a glucosamine-nitrosourea, is a DNA alkylating agent that enters cells exclusively via the GLUT2 glucose transport protein. Streptozocin, a diabetagen, is especially toxic to pancreatic islet insulin-producing β-cells. It is toxic to GLUT2 positive neuroendocrine tumor cells.
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#: 20864.320
: VWR Chemicals
#: 83640.320
: VWR Chemicals
#: 31770.294
: VWR Chemicals
#: 83645.320
: VWR Chemicals