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Proteins and Peptides

Proteins are used in routine laboratory procedures such as binding enzymes or coupling peptides to carrier proteins. These kits, mixture solutions, and collagen matrices fulfill a myriad of essential laboratory functions for developing relationships between proteins and other cellular components. The stimulating proteins offered have various amino acid arrangements and functions to fulfill any sample manipulation for testing purposes in any field.

Aprotinin (Trypsin inhibitor, pancreatic basic) (from bovine lung), proteomics grade

Aprotinin (Trypsin inhibitor, pancreatic basic) (from bovine lung), proteomics grade

Supplier: VWR Chemicals

A competitive and reversible serine protease inhibitor of chymotrypsin, trypsin, kallikrein and plasmin. Not an inhibitor of Factor Xa and thrombin.

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VWR®, Gelatin

VWR®, Gelatin

Supplier: VWR Chemicals

VWR®, Gelatin

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VWR®, Gelatin

VWR®, Gelatin

Supplier: VWR Chemicals

Fluorescence: 238 to 282
E. coli: equivalent
Water content: < or > 13%
pH at 25 °C: 4,0 - 5,7
Salmonella: not detectable
Standard plate count: ≤1000 /g
Viscosity: 38 to 50 mps

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Casein

Supplier: Merck

Casein

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VWR®, Gelatin

VWR®, Gelatin

Supplier: VWR Chemicals

VWR®, Gelatin

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West Nile virus (WNV) matrix protein peptide (15 aa near C-terminus)

Supplier: ProSci Inc.

West Nile virus peptide is used for blocking the activity of West Nile Virus Matrix Protein antibody.

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Human Recombinant NAP-2 (from E. coli)

Human Recombinant NAP-2 (from E. coli)

Supplier: Shenandoah Biotechnology

Neutrophil activating peptide 2 (NAP-2), also known as CXCL7, is a member of the CXC family of chemokines. NAP-2 is a carboxyl-terminal fragment produced by proteolytic cleavage of the platelet basic protein (PBP). NAP-2 is released from platelets and binds to the receptors CXCR1 and CXCR2 to chemoattract and activate neutrophils during inflammatory events.

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J.T.Baker®, Chicken Native Albumin (from Egg)

J.T.Baker®, Chicken Native Albumin (from Egg)

Supplier: Avantor

J.T.Baker®, Chicken Native Albumin (from Egg)

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VWR®, Leupeptin hemisulphate

VWR®, Leupeptin hemisulphate

Supplier: VWR Chemicals

A reversible inhibitor of cysteine proteases and serine proteases resembling trypsin. Inhibits trypsin, plasmin, papain, kallikrein, thrombin, and cathepsin A and B.

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VWR®, Leupeptin hemisulphate

VWR®, Leupeptin hemisulphate

Supplier: VWR Chemicals

A reversible inhibitor of cysteine proteases and serine proteases resembling trypsin. Inhibits trypsin, plasmin, papain, kallikrein, thrombin, and cathepsin A and B.

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VWR®, Bovine serum albumin (BSA)

VWR®, Bovine serum albumin (BSA)

Supplier: VWR Chemicals

A protease-free grade albumin for RIA and ELISA applications, produced by a heat-shock process in caprylic acid.

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Bovine serum albumin (BSA), Fraction V

Supplier: Merck

Bovine serum albumin (BSA), Fraction V

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Poly-L-lysine hydrobromide

Supplier: SIGMA ALDRICH MICROSCOPY

Poly-L-lysine is a positively charged amino acid polymer with approximately one HBr per lysine residue. The hydrobromide allows the poly-L-lysine to be in a crystalline form soluble in water. A small amount of product may be found in the beta structure because the HBr interferes with hydrogen bonding between amino and either the carboxyl groups or N or O containing moieties.

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VWR®, Glycylglycine (Gly-Gly)

VWR®, Glycylglycine (Gly-Gly)

Supplier: VWR Chemicals

Biological buffers are useful for cell culture in vitro, enzyme assays and some electrophoretic applications at physiological pH.

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VWR®, Bovine serum albumin (BSA)

VWR®, Bovine serum albumin (BSA)

Supplier: VWR Chemicals

A higher purity product than standard grade or Cohn fraction V material. It is negative for globulins that interfere in many assays.

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MG-132

MG-132

Supplier: ENZO LIFE SCIENCES

MG-132 is a potent, cell permeable and selective proteasome inhibitor (Ki = 4 nM).1 It inhibits NF-κB activation by preventing IκB degradation (IC50 = 3 μM). The peptide blocks degradation of short-lived proteins, which in turn induces HSP and ER chaperone expression, leading to thermotolerance (1 μM MG-132, 2 h.). It also stimulates neurite outgrowth in PC12 cells (20 nM optimal). The peptide has also been reported to increase the survival rate of mesenchymal stem cells following their transplantation. IC50’s for inhibition of Suc-LLVY-AMC and Z-LLL-AMC cleaving activities of proteasome were 0,85 and 0,1 μM respectively. The ubiquitin-proteasome system (UPS) and autophagy serve as two complementary, reciprocally regulated protein degradation systems, thus blockade of UPS by MG-132 activates autophagy.

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VWR®, Casein

VWR®, Casein

Supplier: VWR Chemicals

Proteins (on anhydrous product): ≥ 90,0 %
Free acidity: Max. 1,0%
Fats: Max. 2,5%
Ignition residue (SO₄): Max. 2,75%
Loss on drying: Max. 12%

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VWR®, Bovine serum albumin (BSA)

VWR®, Bovine serum albumin (BSA)

Supplier: VWR Chemicals

Produced by a heat shock process using sodium caprylate as a stabiliser with additional treatments including dialysis and deionisation.

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Human Recombinant Coagulation factor IX (from Cells)

Supplier: ProSci Inc.

Coagulation factor IX(F9), is a member of the peptidase S1 family. It contains two EGF-like domains, a Gla domain and a peptidase S1 domain. It is primarily expressed in the liver and secreted in plasma. Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ ions, phospholipids, and factor VIIIa. Mutations in position 43 and 46 prevents cleavage of the propeptide, mutation in position 93 probably fails to bind to cell membranes, mutation in position 191 or in position 226 prevent cleavage of the activation peptide. Mutations of human F9 can result in thrombophilia and recessive X-linked hemophilia B (HEMB). An X-linked blood coagulation disorder characterized by a permanent tendency to hemorrhage, due to factor IX deficiency. It is phenotypically similar to hemophilia A, but patients present with fewer symptoms. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma.

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VWR®, Pepstatin A

VWR®, Pepstatin A

Supplier: VWR Chemicals

An aspartic acid protease inhibitor of pepsin, renin, and cathepsin D. Also an inhibitor of the HIV protease. Not water soluble.

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VWR®, Streptavidin (from Streptomyces avidinii)

VWR®, Streptavidin (from Streptomyces avidinii)

Supplier: VWR Chemicals

A 60 kDa tetrameric protein that exhibits high binding affinity for biotin. Able to bind one molecule of biotin with each subunit, streptavidin is useful in affinity chromatography, ELISA, immunohistochemistry, and Western Blotting.

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VWR®, Bovine serum albumin (BSA)

VWR®, Bovine serum albumin (BSA)

Supplier: VWR Chemicals

A standard grade albumin for basic applications, produced by a heat shock process in caprylic acid.

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VWR®, Bovine serum albumin (BSA), Cohn fraction V

VWR®, Bovine serum albumin (BSA), Cohn fraction V

Supplier: VWR Chemicals

A Cohn fraction V albumin produced by cold ethanol fractionation with minimum use of chemicals. Fatty acids and native sialic acid residues are preserved in this BSA.

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Human/Mouse Recombinant TGF-B 3 (from E. coli)

Supplier: Shenandoah Biotechnology

Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-β family of proteins signal through serine/threonine kinase receptors. TGF-β isoforms (TGF-β1, -β2, and –β3) have overlapping, yet distinct biological actions in developing and adult tissues. TGF-β3 is an important factor in regulating cell adhesion and accelerating wound repair. TGF-β3 also functions during osteoblast proliferation, chemotaxis, and collagen synthesis.

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Human/Mouse Recombinant TGF-B 3 (from E. coli)

Supplier: Shenandoah Biotechnology

Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-β family of proteins signal through serine/threonine kinase receptors. TGF-β isoforms (TGF-β1, -β2, and –β3) have overlapping, yet distinct biological actions in developing and adult tissues. TGF-β3 is an important factor in regulating cell adhesion and accelerating wound repair. TGF-β3 also functions during osteoblast proliferation, chemotaxis, and collagen synthesis.

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Peptide A

Supplier: ENZO LIFE SCIENCES

Src kinase inhibitor

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YEEI peptide

Supplier: ENZO LIFE SCIENCES

Src kinase activator

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Terlipressin

Supplier: Apollo Scientific

Terlipressin

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Filamin

Supplier: Apollo Scientific

Filamin

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Ta1

Supplier: Apollo Scientific

Ta1

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