Nucleic Acid Modification and Labelling

Supplier: Abcam

Abcam's Oligonucleotide Conjugation Kit (ab218260) offers several standout features: - Rapid Conjugation: enables generation of antibody-oligonucleotide conjugates in less than 2 hours. - High Efficiency: achieves high levels of antibody and oligonucleotide recovery, with conjugation efficiency ~ 95-100%. - Versatility: Suitable for conjugating antibodies to single-stranded oligonucleotides (10-120 bases) and double-stranded oligonucleotides (up to 80 bases), providing flexibility for various research needs

Supplier: Enzo Life Sciences

High sensitivity, low background streptavidin-based nanopolymer detection reagent for use with HIGHDEF® chromogens in ISH and IHC applications.

Supplier: Thermo Fisher Scientific

T4 DNA Polymerase catalyses the 5'→3' synthesis of DNA from a primed single-stranded DNA template.

Supplier: G-Biosciences

T4 UvsX DNA recombinase mediates DNA strand exchange between homologous chromosomes. The protein forms a right-handed nucleoprotein complex on single ssDNA called the presynaptic filament that can search for homology in duplex DNA and pair the recombining DNA molecules to form a DNA joint molecule. This process is aided by ssDNA binding proteins and recombination mediators. The filament is then elongated by DNA polymerase with the newly synthesised strand displacing the old strand. The newly synthesised duplex DNA can then act as a template for the next cycle to achieve exponential amplification of dsDNA. E.coli cells expressing recombinant T4 UvsX gene.

Supplier: Enzo Life Sciences

Rapid removal of contaminating DNA in PCR mastermixes, without reduction in PCR sensitivity.

Supplier: AAT Bioquest

ReadiView™ Blue Real-Time PCR Visualisation Dye is a 200X concentrated, ready-to-use, inert dye that enhances the visibility of real-time PCR reactions for more accurate pipetting and plate loading.

Supplier: FINNZYMES REAGENTS

Phusion® Site-Directed Mutagenesis Kit is a versatile and efficient tool for introducing point mutations, insertions, or deletions in any type of plasmid DNA.

Supplier: AAT Bioquest

Tyramide signal amplification (TSA) is a technique used to enhance the signal of target molecules, such as antibodies or nucleic acid probes.

Supplier: AAT Bioquest

Tyramide signal amplification (TSA) is a technique used to enhance the signal of target molecules, such as antibodies or nucleic acid probes, in immunohistochemistry and in situ hybridisation.

Supplier: MP Biomedicals

Hybrisol VII

Supplier: Genscript

ABE8e is an innovative adenine base editor designed to enable precise genetic modifications by converting A-T base pairs to G-C base pairs without introducing double-stranded breaks or requiring donor DNA templates.​ABE8e contains eight additional mutations in the TadA domain, augments the effectiveness and applicability of adenine base editing.

Supplier: Promega

T4 DNA Polymerase catalyses the 5´→3´ synthesis of DNA from a primed single-stranded DNA template.

Supplier: Promega

The DNA polymerase I large (Klenow) fragment mini kit provides polymerase and dNTPs ready to use in a variety of applications.

Supplier: Promega

DNA Polymerase I Large (Klenow) Fragment is a 68kDa C-terminal fragment of E. coli DNA Polymerase I that lacks the 5´→3´ exonuclease activity of intact DNA polymerase I but retains its 5´→3´ polymerase, 3´→5´ exonuclease and strand displacement activities.

Supplier: Promega

DNA Polymerase I catalyses the template-directed polymerisation of nucleotides into duplex DNA in a 5´→3´ direction. DNA Polymerase I possesses a 3´→5´ exonuclease activity or 'proofreading' function, which lowers the error rate during DNA replication, and also contains a 5´→3´ exonuclease activity, which enables the enzyme to replace nucleotides in the growing strand of DNA by nick translation.

Supplier: Promega

DNA Polymerase I Large (Klenow) Fragment, Exonuclease Minus, is a DNA-dependent DNA polymerase that lacks both the 5´→3´ and the 3´→5´ exonuclease activities present in intact E. coli DNA polymerase I.