You searched for: pro-Luciferin substrate

Supplier: Promega

The pro-luciferin substrates can be used to monitor the activity of specific isoforms of cytochrome P450 or NAT2 as indicated in the name of the substrate.

Supplier: Promega

The pro-luciferin substrates can be used to monitor the activity of specific isoforms of cytochrome P450 or NAT2 as indicated in the name of the substrate.
The luciferin derivative, 2-(6-(4-chlorobenzyloxy)benzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid, referred to as Luciferin-4F12, is selectively converted to luciferin by the human CYP4F12 enzyme.

Supplier: Promega

The pro-luciferin substrates can be used to monitor the activity of specific isoforms of cytochrome P450 or NAT2 as indicated in the name of the substrate.
The luciferin derivative, 2-hydroxyethyl 2-(6-(3,3-dimethoxypropoxy)benzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylate, referred to as Luciferin-2J2/4F12, is converted to a luciferin ester, most prominently by CYP2J2 and to a lesser extent by CYP4F12, CYP1A1, CYP1B1 and CYP3A4. The Luciferin-2J2/4F12 substrate is selective for human CYP2J2, CYP4F12, CYP3A4, CYP1A1 and CYP1B1, and has a strong preference for CYP2J2 under conditions that favor activity of this enzyme.

Supplier: Promega

The pro-luciferin substrates can be used to monitor the activity of specific isoforms of cytochrome P450 or NAT2 as indicated in the name of the substrate.
The luciferin derivative, 2-(6-(4-(methylthio)benzyloxy)benzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid, referred to as Luciferin-4F2/3, is shown to have a high degree of selectivity for CYP4F3B and CYP4F2.

Supplier: Promega

The pro-luciferin substrates can be used to monitor the activity of specific isoforms of cytochrome P450 or NAT2 as indicated in the name of the substrate.
The bis-luciferin, 2,2’-(6,6’-(1,3-phenylenebis(methylene))bis(oxy)bis(benzo[d]thiazole-6,2-diyl))bis(4,5-dihydrothiazole-4-carboxylic acid), referred to as Luciferin-3A7, is selectively converted to luciferin by the human CYP3A7 enzyme with little or no detectable activity with CYP3A4 or CYP3A5.

Supplier: Promega

The pro-luciferin substrates can be used to monitor the activity of specific isoforms of cytochrome P450 or NAT2 as indicated in the name of the substrate.
The promiscuous CYP substrate, methyl 2-(6-methoxybenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylate, referred to as Luciferin-MultiCYP, reacts with at least 21 CYP enzymes.