913 Results for: "Test Lead"

Supplier: Biotix

The exclusive S³ polymer delivers to within 0.1% of indicated volume, eliminating sample hold-up and ensuring a more precise application.

Supplier: Cayman Chemical Company

An active, pure human recombinant enzyme.

Supplier: Promega Corporation

The GSH-Glo Assay is a luminescent-based assay for the detection and quantification of glutathione (GSH) in cells or in various biological samples.

Supplier: Bel-Art Products, a Part of SP

Achieve perfect beer brewing and wine making results with DURAC Triple Scale Beer and Wine Hydrometers. Includes three scales, Specific Gravity, Potential Alcohol by Volume (PAV), and Brix, that provide invaluable data points when crafting beer, wine, kombucha, mead, cider, and more in either a commercial or home brew setting.

Supplier: VWR International

This thermometer features an easy-to-read “HeadsUp” view, and the thermometer’s waterproof construction is ideal for wet labs, wash-down areas, and field applications.

Supplier: VWR International

A stainless steel fold-up protected probe permits carrying on the wrist-strap or in a pocket.

Supplier: Cytiva

Whatman Puradisc Aqua 30 from Cytiva's business is specifically designed for environmental sample filtration prior to dissolved organic carbon (DOC) and chemical oxygen demand (COD) analysis.

Supplier: DRG International

An enzyme immunoassay for the quantitative determination of free prostate specific antigen (f-PSA) in serum or plasma.

Supplier: Thermo Fisher Scientific

Accurately monitor pH, ion concentration, mV, ORP, and temperature with the Orion™ Star™ A324 pH/ISE Portable Meter for challenging field testing.

Supplier: Scientific Industries

Economical alternative to ultransonic disruptors.

Supplier: Biotix

The exclusive S³ polymer delivers to within 0.1% of indicated volume, eliminating sample hold-up and ensuring a more precise application.

Supplier: Biotium

CD16 (Clone 3G8) is a mouse monoclonal antibody that recognizes IgG receptor CD16, also known as FC gamma receptor III. This antibody belongs to the Biotium Choice list of select antibodies that have been validated and optimized in-house for optimal performance. The antibody is available conjugated to CF® Dyes and Astral™ tandem dyes. They are supplied in PBS, 0.1% BSA, 0.05% azide.

Supplier: Bel-Art Products, a Part of SP

FRIO-Temp® Thermometers are used to verify temperatures in freezers, refrigerators, incubators and ovens with traceability to most ILAC standards.

Supplier: Quantabio

Superior speed and inhibitor tolerance.

Supplier: Biosensis

TrkA is a member of the neurotrophic tyrosine kinase receptor family. It is a membrane-bound receptor that upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TrkA is required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). TrkA leads to cell differentiations and may play a role in specifying sensory neuron subtypes. It has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. SUBUNIT: Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures. SUBCELLULAR LOCATION: Cell membrane; single-pass type I membrane protein. Endocytosed to the endosomes upon treatment of cells with NGF. ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. Both isoforms have similar biological properties. TISSUE SPECIFICITY: Isoform TrkA-II is primarily expressed in neuronal cells. Isoform TrkA-I is found in non-neuronal tissues. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutalating behaviour, mental retardation and cancer (Reference: www.uniprot.com). Antibody reacts with human TrkA. Does not cross-react with TrkB or TrkC.

Supplier: Biotium

CD16 (Clone 3G8) is a mouse monoclonal antibody that recognizes IgG receptor CD16, also known as FC gamma receptor III. This antibody belongs to the Biotium Choice list of select antibodies that have been validated and optimized in-house for optimal performance. The antibody is available conjugated to CF® Dyes and Astral™ tandem dyes. They are supplied in PBS, 0.1% BSA, 0.05% azide.

Supplier: WORLD PRECISION INSTRUMENTS LLC

The A385 is an optically isolated current source, which can generate up to 100 mA of unipolar or biphasic constant current pulses or DC. Pulse duration is controlled manually or by an external 5 V command. Output current amplitude is determined by a 3-digit 10-turn potentiometer. Maximum output voltage between the stimulating electrodes is +36 V.

Supplier: Desco

This aluminized moisture barrier bag is designed to provide packaging for ESD and moisture sensitive items, both inside and outside an ESD protected area. The bags are heat sealable and suitable for vacuum packaging.

Supplier: Biotium

CD16 (Clone 3G8) is a mouse monoclonal antibody that recognizes IgG receptor CD16, also known as FC gamma receptor III. This antibody belongs to the Biotium Choice list of select antibodies that have been validated and optimized in-house for optimal performance. The antibody is available conjugated to CF® Dyes and Astral™ tandem dyes. They are supplied in PBS, 0.1% BSA, 0.05% azide.

Supplier: Electron Microscopy Sciences

Evaporization controlled automated embedding and polymerization. The EMS Poly III is an instrument for the embedding of specimens by the proper combination of pressure and temperature.

Supplier: Bel-Art Products, a Part of SP

Enviro-Safe® Thermometers feature Enviro-Safe liquid, the only EnviroKleen™ certified environmentally friendly thermometer liquid available on the market.

Supplier: I.W. TREMONT CO., INC.

Unlike traditional polymeric cast film membranes, H&V Trupor® NYLON and PES membrane utilizes a composite design to achieve precisely regulated porosities with best-in-class performance which significantly reduces trace extractables making it an ideal matrix for analytical separations.

Supplier: Memmert

Memmert’s Cooled Storage Incubator (IPPeco) is the most energy-efficient and powerful cooled incubator of its kind due to state-of-the-art Peltier technology. Heat-up, cool down and recovery times are much shorter than comparable incubators. The Peltier-cooled incubator from Memmert saves on operating costs, ensures sample uniformity and makes work more efficient. 

Supplier: Cytiva

nProtein A Sepharose 4 Fast Flow is native protein A coupled to the well established Sepharose 4 Fast Flow base matrix.

Supplier: Eppendorf

Eppendorf twin.tec® real-time PCR plates, designed for low-volume qPCR, utilize white wells to enhance fluorescent light reflection, improving sensitivity and reproducibility in assays for reliable results.

Supplier: Cayman Chemical Company

An active, pure human recombinant enzyme.

Supplier: BioVendor

Glycosaminoglycans (GAGs) are large complex carbohydrate molecules that interact with a wide variety of proteins involved in physiological and pathological processes. GAGs are also known as mucopolysaccharides due to their viscous, lubricating properties, as found in mucous secretions. GAGs are found on all animal cell surfaces in the extracellular matrix (ECM), and some are known to bind and regulate certain proteins, including chemokines, cytokines, growth factors, morphogens, enzymes and adhesion molecules.

GAGs are linear, sulphated, negatively charged polysaccharides that have molecular weights of approximately 10–100 kDa. GAGs can be divided into two main types. Non‐sulphated GAGs include hyaluronic acid (HA), whereas sulphated GAGs include chondroitin sulphate (CS), dermatan sulphate (DS), keratan sulphate (KS), heparin and heparan sulphate (HS).

GAGs play an important role in cell signaling and development, angiogenesis, axonal growth, tumour progression, metastasis and anti‐coagulation. Uncontrolled progenitor cell proliferation leads to malignant tissue transformation and cancer. GAGs and proteoglycans (PGs) are believed to play a critical role in cell proliferation, acting as co‐receptors for growth factors of the fibroblast growth factor (FGF) family.

PGs are composed of a core protein to which one or more GAG chains are covalently attached. Examples of large PGs are aggrecan, the major PG in cartilage, and versican, which is present in numerous adult tissues such as blood vessels and skin. PGs are known to have a variety of functions, dependent on type and in vivo location, and have important roles in invertebrate and vertebrate development, maintenance, and tissue repair. Many biologically potent small proteins can bind GAG chains as a major part of their function in the ECM, at the cell surface, and also in some intracellular locations. Thus, PGs have become a major focus in research on many diseases.

Supplier: Anaspec Inc

Factor Xa (FXa) is a serine endopeptidase composed of two disulfide-linked subunits

Supplier: VWR International

The VWR® Flammable Storage Refrigerators are designed to meet the requirements of NFPA 45 and NFPA 30 for cold storage of flammable and combustible materials in unclassified laboratory locations.

Supplier: Prosci

Kinase subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Amino-acid-signaling to mTORC1 is mediated by Rag GTPases, which cause amino-acid-induced relocalization of mTOR within the endomembrane system. Growth factor-stimulated mTORC1 activation involves AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1 at 'Thr-421', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'.