671 Results for: "Stemcell Technologies"

Supplier: STEMCELL Technologies

Medium for preparing and washing samples for CFU assays.

Supplier: STEMCELL Technologies

10X Collagenase/hyaluronidase in DMEM.

Supplier: STEMCELL Technologies

Serum-free culture supplement for expansion of human erythroid cells.

Supplier: STEMCELL Technologies

Hybridoma selection medium, with HAT (serum-containing).

Supplier: STEMCELL Technologies

Hybridoma growth medium with hypoxanthine and thymidine (serum-containing).

Supplier: STEMCELL Technologies

Differentiation kit for the generation of sensory neuronal precursors from human iPS cell-derived neural crest cells.

Supplier: STEMCELL Technologies

Maturation kit for generation of functional sensory neurons from human iPS cell-derived neuronal precursor cells.

Supplier: STEMCELL Technologies

Immunomagnetic negative selection of human pan-B cells

Supplier: STEMCELL Technologies

For differentiation of human PSCs into the hematopoietic lineage.

Supplier: STEMCELL Technologies

Immunomagnetic negative selection kit

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of mouse cells labeled with biotinylated antibodies.

Supplier: STEMCELL Technologies

Column-free immunomagnetic positive selection of human B cells for HLA analysis.

Supplier: STEMCELL Technologies

Platelet-derived growth factor (PDGF) is a dimeric glycoprotein consisting of two disulfide bridge-stabilized polypeptide chains, A and B, which are assembled as heterodimers (PDGF-AB) or homodimers (PDGF-AA and PDGF-BB) (Fretto et al.; Westermark and Heldin). PDGF signals through the receptor tyrosine kinases PDGFRalpha and PDGFRbeta. It has been shown that PDGF-induced migration involves signaling pathways involving MEK/ERK, EGFR, Src, and PI3K/AKT (Kim et al.). PDGF is a potent mitogen for cells of mesenchymal origin, such as fibroblasts, glial cells, and vascular smooth muscle cells. PDGF has been implicated in pathogenesis of atherosclerosis, glomerulonephritis, cancer, and in the contraction of vascular smooth muscle cells of rat aortic tissues (Fretto et al.; Sachinidis et al.). It has been suggested that PDGF-AA is an important autocrine regulator of vascular endothelial growth factor (VEGF) expression in non-small cell lung carcinomas (Shikada et al.). PDGF-AA also mediates proliferation of oligodendrocyte progenitor cells and oligodendrocyte lineage differentiation through the activation of extracellular signal-regulated kinases 1 and 2 (ERK1/2) (Hu et al.). PDGF-AA is commonly used to differentiate human pluripotent stem cell (hPSC)-derived neural progenitor cells into oligodendrocyte precursor cells (Piao et al.).

Supplier: STEMCELL Technologies

Interleukin 6 (IL-6) is a pleiotropic growth factor with the wide range of biological activities in immune regulation, hematopoiesis, and oncogenesis. IL-6 is produced by a variety of cell types including T cells, B cells, monocytes and macrophages, fibroblasts, hepatocytes, vascular endothelial cells, and various tumor cell lines. On its own or in combination with other factors such as IL-2 and interferon-γ, IL-6 stimulates the proliferation of B cells, T cells, and hybridoma cells (Hirano et al.; Mihara et al.; Tanaka et al). In combination with cytokines such as IL-3, GM-CSF and SCF, IL-6 has been shown to promote hematopoietic progenitor cell proliferation and differentiation in vitro. IL-6 signals through a cell surface type I cytokine receptor complex consisting of the ligand-binding IL-6α (CD126) and the signal-transducing gp130 subunits. The binding of IL-6 to its receptor system includes activation of JAK/STAT signaling pathway (Mihara et al.; Peters et al.; Tanaka et al.).

Supplier: Stemcell Technologies

cGMP, stabilised feeder-free maintenance medium for human ES and iPS cells.

Supplier: Stemcell Technologies

Defined, serum-free medium for generation and culture of embryoid bodies using AggreWell™ plates.

Supplier: STEMCELL Technologies

Serum-free media for generation and maturation of branching lung organoids from human ES and iPS cells.

Supplier: STEMCELL Technologies

Base methylcellulose medium for mouse cells.

Supplier: STEMCELL Technologies

Methylcellulose-based medium with recombinant cytokines (without EPO) for mouse myeloid progenitor cells.

Supplier: STEMCELL Technologies

Immunodensity isolation of untouched myeloid cells for lineage-specific chimerism analysis.

Supplier: STEMCELL Technologies

Kit for enzymatic dissociation of adult mouse and rat CNS tissue.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched human myeloid dendritic cells (mDCs).

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of any cells labeled with PE-conjugated antibodies.

Supplier: STEMCELL Technologies

Animal component-free medium for the differentiation of MSCs into chondrocytes.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched human NK cells.

Supplier: STEMCELL Technologies

CryoStor® CS10 is a uniquely formulated, serum-free, animal component-free and defined cryopreservation medium containing 10% dimethyl sulfoxide (DMSO). Designed to preserve cells in low temperature environments (-80 °C to -196 °C).

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched human naïve B cells

Supplier: STEMCELL Technologies

Immunodensity isolation of untouched B cells.

Supplier: STEMCELL Technologies

Heregulin-beta 1 also known as neuregulin-1 (NRG-1) is a member of the epidermal growth factor (EGF) family of growth factors and acts as a ligand for ErbB family receptor tyrosine kinases (Britsch et al.). Heregulin/neuregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3, and NRG4). Heregulin-beta 1 plays an important role during the development of the nervous system, heart, and mammary glands (Britsch). Heregulin-beta 1 is expressed in neuronal cells, and modulates cell growth and differentiation of the cells during development and wound healing (Mei and Xiong). It has been implicated through in vivo and in vitro studies that heregulin-beta 1/ErbB signaling is crucial for multiple aspects of cardiovascular development and protects the heart from ischemic injury (Odiete et al.). Heregulin-beta 1 also promotes invasiveness and metastasis of breast cancer cells (Hutcheson et al.). It has also been shown that heregulin-beta 1 has a role in the growth and maintenance of human embryonic stem cells (Wang et al.).

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched mouse T cells