"Stemcell Technologies"

Supplier: Stemcell Technologies

cGMP, enzyme-free human pluripotent stem cell selection and passaging reagent.

Supplier: Stemcell Technologies

Membrane-permeable fluorescent probe for the detection of live neurons - 0.1 ml.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2b antibody against human, rhesus, cynomolgus CD32, unconjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human CD56 (NCAM), Alexa Fluor® 488-conjugated.

Supplier: Stemcell Technologies

Fast and easy isolation of human extracellular vesicles using immunomagnetic positive selection.

Supplier: Stemcell Technologies

Differentiation kit for the generation of astrocyte precursors from human ES and iPS cell-derived neural progenitor cells.

Supplier: Stemcell Technologies

Iscove's Modified Dulbecco's Medium (IMDM) with 25 mm HEPES.

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched human B cells without CD43 depletion.

Supplier: Stemcell Technologies

Animal origin-free, serum-free, L-glutamine-free, and phenol red-free 40X culture supplement for cloning during CHO cell line development.

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched mouse pan-B cells

Supplier: Stemcell Technologies

Stem cell factor (SCF) is an early-acting cytokine that plays a pivotal role in the regulation of embryonic and adult hematopoiesis. SCF promotes cell survival, proliferation, differentiation, adhesion, and functional activation of cells at multiple levels of the hematopoietic hierarchy. Together with other cytokines such as thrombopoietin and Flt3/Flk-2 Ligand, SCF is commonly used to promote expansion of primitive hematopoietic stem cells and multi-potent progenitor cells in culture (Martin et al.; Kent et al.). In synergy with various growth factors, including IL-2, IL-3, IL-6, IL-7, G-CSF, and erythropoietin, SCF increases proliferation and differentiation of myeloid and erythroid progenitor cells and a subset of lymphoid progenitor cells (Broudy). SCF is also a primary growth and activation factor for mast cells and eosinophils. SCF exists in two biologically active splice forms: a soluble and a transmembrane isoform. Upon binding to its receptor (c-Kit tyrosine kinase receptor; CD117), it activates PI3K, JAK/STAT, and MAPK pathways. SCF and signaling from c-Kit have also been reported to play an important role in pigmentation, fertility, vasculogenesis, motility of the gut via c-Kit positive interstitial cells of Cajal, and in the migration of neuronal stem and progenitor cells to sites of injury in the brain. This product is animal component-free.

Supplier: Stemcell Technologies

Human Interleukin 4 (IL-4) is important for immune responses to helminth infection as well as in allergic responses (Olpihant et al.). The IL-4 receptor consists of a heterodimer of IL-4Ra and common gamma chain. IL-4 receptor engagement leads to the activation of JAK1/3 and the recruitment of STAT6 and IRS1/2 (Nelms et al.). IL-4 drives immunoglobulin class switching in B cells (to IgE, IgG4), mast cell hyperplasia, mucus production, and the differentiation of naïve T cells into Th2 cells, which produce IL-4, IL-5, IL-10, and IL-13 (Bao et al.; Nelms et al.; Olpihant et al.). In addition to Th2 cells, IL-4 is produced by CD4+ NK T cells, γ/δ T cells, activated basophils, eosinophils, and mast cells. Human IL-4 does not cross-react with mouse cells (Park et al.).

Supplier: Stemcell Technologies

50 ml centrifuge tube with an insert for density gradient centrifugation

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched human pan dendritic cells (DC)

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched mouse neutrophils

Supplier: Stemcell Technologies

Semi-solid methylcellulose-based medium for hybridoma selection and cloning, with HAT (serum-containing).