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659 results for "Stemcell Technologies"

"Stemcell Technologies"

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Human Recombinant BDNF

Human Recombinant BDNF

Supplier: Stemcell Technologies

Brain-derived neurotrophic factor (BDNF), like nerve growth factor (NGF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4), is a member of the NGF family of neurotrophins, which are required for the differentiation and survival of specific neuronal subpopulations in both the central and the peripheral nervous systems (Minichiello and Klein; Minichiello et al.). BDNF binds with high affinity to the tropomyosin receptor kinase B (TrkB), and activates AKT and ERK pathways (Mattson et al.). It is expressed in the hippocampus, cortex, and synapses of the basal forebrain. BDNF acts as a survival factor for human embryonic stem cells when plated on either feeder cells or Corning® Matrigel® (Pyle et al.). BDNF regulates synaptic transmission and plasticity at adult synapses in the central nervous system, and contributes to adaptive neuronal responses including long-term potentiation, long-term depression, certain forms of short-term synaptic plasticity, and homeostatic regulation of neuronal excitability (Reichardt). It also has a role in neurogenesis by promoting survival and growth of dorsal root ganglion cells, and hippocampal and cortical neurons (Binder and Scharfman). BDNF, together with glial cell line-derived neurotrophic factor (GDNF) and other supplements, is commonly used to differentiate human pluripotent stem cell (hPSC)-derived neural progenitor cells into neurons (Brafman).

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Anti-Igg2b Isotype Control Mouse Monoclonal Antibody [clone: MPC-11] (Alexa Fluor® 488)

Anti-Igg2b Isotype Control Mouse Monoclonal Antibody [clone: MPC-11] (Alexa Fluor® 488)

Supplier: Stemcell Technologies

Mouse monoclonal IgG2b, kappa isotype control antibody, Alexa Fluor® 488-conjugated.

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StemSpan™ Myeloid Expansion Supplement II (100X)

StemSpan™ Myeloid Expansion Supplement II (100X)

Supplier: Stemcell Technologies

Serum-free culture supplement for expansion and differentiation of human monocytes.

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EasySep™ Human Myeloid DC Enrichment Kits

EasySep™ Human Myeloid DC Enrichment Kits

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched human myeloid dendritic cells (mDCs).

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EasySep™ Mouse CD8+ T Cell Isolation Kits

EasySep™ Mouse CD8+ T Cell Isolation Kits

Supplier: Stemcell Technologies

Isolate untouched and highly purified CD8+ T cells from mouse splenocytes by immunomagnetic negative selection. When using single-cell suspensions from other tissue types, this kit may require optimization.

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MethoCult™ SF H4636 Medium

MethoCult™ SF H4636 Medium

Supplier: Stemcell Technologies

Serum-free methylcellulose-based medium with recombinant cytokines for human ES and iPS cell-derived cells.

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EasySep™ Mouse T Cell Isolation Kits

EasySep™ Mouse T Cell Isolation Kits

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched mouse T cells

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ImmunoCult™-XF Medium

ImmunoCult™-XF Medium

Supplier: Stemcell Technologies

cGMP, serum-free, and xeno-free medium for the expansion of human T cells.

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STEMdiff™ APEL™2 Medium

STEMdiff™ APEL™2 Medium

Supplier: Stemcell Technologies

Defined, animal component-free medium for differentiation of human ES and iPS cells to multiple lineages.

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EasySep™ Human Naïve B Cell Enrichment Kits

EasySep™ Human Naïve B Cell Enrichment Kits

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched human naïve B cells

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EasySep™ Mouse CD8a Positive Selection Kit II

EasySep™ Mouse CD8a Positive Selection Kit II

Supplier: Stemcell Technologies

Immunomagnetic positive selection of CD8a+ cells from mouse splenocytes or other tissues.

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EasySep™ Direct Human CD8+ T Cell Isolation Kit

EasySep™ Direct Human CD8+ T Cell Isolation Kit

Supplier: Stemcell Technologies

Immunomagnetic isolation of CD8+ T cells directly from whole blood

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RosetteSep™ HLA Myeloid Cell Enrichment Kit

RosetteSep™ HLA Myeloid Cell Enrichment Kit

Supplier: Stemcell Technologies

Immunodensity isolation of untouched myeloid cells for lineage-specific chimerism analysis.

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MethoCult™ M3134 Medium

MethoCult™ M3134 Medium

Supplier: Stemcell Technologies

Base methylcellulose medium for mouse cells.

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STEMdiff™ Branching Lung Organoid Kit

STEMdiff™ Branching Lung Organoid Kit

Supplier: Stemcell Technologies

Serum-free media for generation and maturation of branching lung organoids from human ES and iPS cells.

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ImmunoCult™ ACF Human B Cell Expansion Supplement

ImmunoCult™ ACF Human B Cell Expansion Supplement

Supplier: Stemcell Technologies

Serum-free and animal component-free culture supplement for expansion of human B cells.

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