680 Results for: "STEMCELL Technologies"

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched human CD4+ T cells.

Supplier: STEMCELL Technologies

Immunodensity isolation of untouched stem/progenitor cells from cord blood.

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of human CD14+ cells (e.g. monocytes).

Supplier: STEMCELL Technologies

Interleukin 2 (IL-2) is a monomeric cytokine that was originally identified as a T cell growth factor (Gaffen and Liu). It binds to heterotrimeric receptors consisting of CD25, CD122, and CD132. Upon binding, it activates JAK3-, STAT5-, and AKT-dependent signaling pathways, which results in cellular proliferation and survival (Ma et al.). The majority of IL-2 is secreted by activated CD4+ and CD8+ T cells, although B cells and dendritic cells were found to produce IL-2 in small amounts. IL-2 downregulates immune responses to prevent autoimmunity during thymic development, influences the development of CD4+CD25+ regulatory T cells, and affects development of follicular helper T cells. IL-2 also controls inflammation by inhibiting Th17 differentiation (Banchereau et al.). High IL-2 levels in serum are associated with progression of scleroderma, rheumatoid arthritis, and gastric and non-small cell lung cancer, though no known disease can be directly attributed to the lack or excess of IL-2 (Gaffen and Liu).

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched human plasmacytoid dendritic cells (pDC)

Supplier: STEMCELL Technologies

Pre-aliquoted methylcellulose-based medium with recombinant cytokines for human cells. 24x3ml vials.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched mouse pan-dendritic cells (DCs)

Supplier: STEMCELL Technologies

Immunomagnetic isolation of mouse naïve CD4+ T cells.

Supplier: STEMCELL Technologies

The EasySep™ magnet is designed for cell separation procedures using EasySep™ reagents.

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of human EpCAM+ cells (e.g. mammary epithelial cells).

Supplier: STEMCELL Technologies

Culture medium kit for expansion of human NK cells.

Supplier: STEMCELL Technologies

Serum-free and xeno-free base medium for the expansion of NK cells.

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of particle-free human CD19+ cells.

Supplier: STEMCELL Technologies

Serum-free methylcellulose-based medium with recombinant cytokines for human cells.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of NK cells directly from whole blood

Supplier: STEMCELL Technologies

Cell culture medium for further differentiation of human intestinal organoids in 3D, or as monolayers/air-liquid interface cultures.

Supplier: STEMCELL Technologies

Kit for generating iPS cells using ReproRNA™-OKSGM, a non-integrating, self-replicating RNA reprogramming vector.

Supplier: STEMCELL Technologies

Bone morphogenetic protein 4 (BMP-4) is a member of the highly conserved transforming growth factor β (TGF-β) superfamily. Mature BMP-4 is a disulfide-linked homodimeric protein consisting of two 116-amino-acid residue subunits, and is generated by the proteolytic removal of the signal peptide and propeptides (Xiao et al.). BMP-4 binds to type I and type II receptors on cells. This binding results in the phosphorylation of receptor 1, which in turn results in the phosphorylation of Smad proteins, which then go on to act as transcription factors (Zhang et al.). BMPs have been shown to be key regulators of embryogenesis and are known to play a role in the growth and differentiation of various cell types, including embryonic stem (ES) cells, induced pluripotent stem (iPS) cells, mesenchymal cells, epithelial cells, hematopoietic cells, and neuronal cells (Chadwick et al.; Graham et al.; Jones et al.; Lengerke et al.; Zhang et al.).

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of CD90.2+ cells from mouse splenocytes or other tissues.

Supplier: STEMCELL Technologies

Immunodensity isolation of untouched NK cells.

Supplier: STEMCELL Technologies

Reliably isolate mononuclear cells from peripheral blood, cord blood, or bone marrow with Lymphoprep™, a cost-effective alternative to Ficoll-Paque™.

Supplier: STEMCELL Technologies

Serum-free culture supplement for expansion of human hematopoietic cells.

Supplier: STEMCELL Technologies

cGMP, feeder-free maintenance medium for human ES and iPS cells.

Supplier: STEMCELL Technologies

Serum-free medium for culture and expansion of hematopoietic cells.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched human peripheral blood mononuclear cells from whole blood

Supplier: STEMCELL Technologies

For depletion of red blood cells from fresh blood samples and isolation of nucleated cells.

Supplier: STEMCELL Technologies

cGMP, enzyme-free cell dissociation reagent.

Supplier: STEMCELL Technologies

Dissociation kit for human stem and progenitor cells.

Supplier: STEMCELL Technologies

The EasySep™ 'The Big Easy' magnet is designed for cell separation procedures using EasySep™ reagents when processing a large number of cells, or when using RoboSep™.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched human CD8+ T cells.