3615 Results for: "SAR-125844&amp"

Supplier: Ambeed

1-(6-((6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)thio)benzo[d]thiazol-2-yl)-3-(2-morpholinoethyl)urea, Purity: 98+%, CAS Number: 1116743-46-4, Appearance: White to yellow powder or crystals, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 5mg

Supplier: Ambeed

SAR-20347 98%

Supplier: ALADDIN SCIENTIFIC

AMP PNP ≥90% (by HPLC)

Supplier: Bachem Americas

Sequence: Z-Sar-OSu

Supplier: Adipogen

SAR-020106 is an ATP-competitive, potent, and selective CHK1 inhibitor with an IC(50) of 13.3nM on the isolated human enzyme. This compound abrogates an etoposide-induced G(2) arrest with an IC(50) of 55nM in HT29 cells, and significantly enhances the cell killing of gemcitabine and SN38 by 3.0- to 29-fold in several colon tumor lines in vitro and in a p53-dependent fashion. Biomarker studies have shown that SAR-020106 inhibits cytotoxic drug-induced autophosphorylation of CHK1 at S296 and blocks the phosphorylation of CDK1 at Y15 in a dose-dependent fashion both in vitro and in vivo.

Supplier: Adipogen

SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells with IC(50) values of 20 and 45nM, respectively. SAR131675 dose dependently inhibited the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD, with an IC(50) of about 20nM. SAR131675 was found to be highly selective for VEGFR-3 versus 107 receptors, enzymes, ion channels, and 65 kinases. However, it was moderately active on VEGFR-2 with a VEGFR-3/VEGFR-2 ratio of about 10. SAR131675 had no antiproliferative activity on a panel of 30 tumors and primary cells, further showing its high specificity and indicating that SAR131675 is not a cytotoxic or cytostatic agent.

Supplier: VWR

5% water has been added to maintain liquidity at room temperature.

Supplier: Bachem Americas

Sequence: Fmoc-Sar-OH

Supplier: AAT BIOQUEST INC

AMP-Fluorescein conjugate calibrator is desigend to use with AAT Bioquests' green fluorescent FAM-cAMP PDE IV substrate, a cAMP derivative that is a specific substrate for phosphodiesterase (PDE) IV.

Supplier: Cayman Chemical Company

Cyclic di-AMP (sodium salt), Purity: >/=98%, A second messenger produced by bacteria, but not by mammals, Synonyms: c-di-AMP, Cyclic di-Adenosine monophosphate, 3',5'-Cyclic diadenylic acid, Cyclic diadenylate, Size: 500ug

Supplier: Ambeed

Fmoc-Sar-OH, Purity: 98% HPLC, CAS Number: 77128-70-2, Appearance: Form: Powder/Colour: White - Yellow, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 25g

Supplier: Ambeed

Z-Gly-Sar-OH, Purity: 98%, CAS Number: 7801-91-4, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, Store in freezer, under -20C, Size: 1G

Supplier: Ambeed

(S)-9-((5-Chloropyridin-3-yl)methyl)-2-((R)-3-methylmorpholino)-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one, Purity: 98+%, CAS Number: 1523406-39-4, Appearance: White to Yellow Solid, Storage: Sealed in dry, Store in freezer, under -20 C, Size: 1mg

Supplier: Enzo Life Sciences

Adenosine 5'-monophosphate disodium salt (AMP disodium salt) ≥98% (by HPLC)

Supplier: Matrix Scientific

MF=C18H19NO5 MW=329.36 CAS=77128-70-2 MDL=MFCD00180724 100G

Supplier: Thermo Scientific Chemicals

100ML

Supplier: Spectrum Chemical Mfg. Corp.

2-Amino-2-methyl-1-propanol, or aminomethyl propanol is a colorless, viscous liquid that functions as a pH adjuster. It is also used as an intermediate in drug synthetic schemes.

Supplier: Matrix Scientific

Matrix Scientific Part Number: 042464-25G , MDL Number: MFCD00151926

Supplier: ALADDIN SCIENTIFIC

Used in the preparation of buffer solutions, suitable for the determination of alkaline phosphatase.2-Amino-2-methyl-1-propanol can be used to study biological buffers. 2-Amino-2-methyl-1-propanol has been used in a study to report on an ATR-FTIR spectroscopic investigation of the CO(2) absorption characteristics of a series of heterocyclic diamines. 2-Amino-2-methyl-1-propanol has also been used in a study to develop a mild and convenient method for preparing 4,4-dimethyloxazoline (DMOX) derivatives of fatty acids for GC-MS analysis.

Supplier: Thermo Scientific Chemicals

N-Fmoc-N-methylglycine, 98%

Supplier: Thermo Scientific Chemicals

Adenosine-5'-monophosphoric acid (AMP) 99%

Supplier: Ambeed

Adenosine-5'-monophosphoric acid (AMP) 97%

Supplier: Ambeed

2-Amino-2-methyl-1-propanol, Purity: 97%, CAS number: 124-68-5, Appearance: Colorless Liquid or Solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 100G

Supplier: Thermo Scientific Chemicals

a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists.

Supplier: TCI America

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methylglycine, Purity: >98.0%(HPLC)(T), CAS number: 77128-70-2, Molecular Formula: C18H17NO4, Molecular Weight: 311.34, Synonym: Fmoc-N-Me-Gly-OH, N-Fmoc-N-methylglycine, Size: 25G

Supplier: TCI America

CAS Number: 61-19-8
MDL Number: MFCD00005750
Molecular Formula: C10H14N5O7P
Molecular Weight: 347.22
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 200

Supplier: MilliporeSigma

Cas Number:124-68-5 250Ml

Supplier: MilliporeSigma

Adenosine 5''-Monophosphate, Disodium. (AMP, sodium). Crystalline solid. Purity: >= 95% by UV. Soluble in H2O. RTECS AU7481600, CAS 4578-31-8, M.W. 391.2.

Supplier: MP Biomedicals

Adenosine 5'-monophosphate disodium salt (AMP disodium salt) hydrate ≥99%, powder

Supplier: Ambeed

Adenosine 5'-monophosphate disodium salt (AMP disodium salt) dihydrate 95%