3580 Results for: "Proteintech"

Supplier: Proteintech

The IQGAP2 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human IQGAP2. This antibody recognizes human antigen. The IQGAP2 antibody has been validated for the following applications: ELISA, IHC, WB analysis.

Supplier: Proteintech

SPIN1, also named as OCR and SPIN, plays a role in cell-cycle regulation during the transition from gamete to embryo. SPIN1 induces necrotic cell death via autophagy. It plays a critical role in necrotic cell death in cultured human cells. SPIN1 bound the antiapoptotic protein BCL2 and the apoptosis regulator BCLXL and induced cell death via a pathway that was independent of mitochondrial cytochrome c release and caspase activation

Supplier: Proteintech

The GAB2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GAB2. This antibody recognizes human, mouse antigen. The GAB2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.

Supplier: Proteintech

CTSD(Cathepsin D) is also named as CPSD,belongs to the peptidase A1 family.It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. The prepro-CTSD isoform has a molecular mass of 52 kDa, the pro-CTSD 48 kDa and the mature CTSD 32 kDa. It is a lysosomal acid protease found in neutrophils and monocytes and involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.Defects in CTSD are the cause of neuronal ceroid lipofuscinosis type 10 (CLN10).This antibody is specific to CTSD.

Supplier: Proteintech

TPPP, also named as TPPP1, P24 and P25, belongs to the TPPP family. TPPP promotes in vitro the polymerization of tubulin into double-walled tubules and polymorphic aggregates or bundled stabilized microtubules blocks. When overexpressed, TPPP inhibits mitotic spindle assembly and nuclear envelope breakdown, apparently without affecting other cellular events.

Supplier: Proteintech

Anti-VPS45(Polyclonal) Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Recombinant Protein, C-term-300 amino acid, Format:Antigen affinity purification, Application: ELISA, WB, Recommended Storage: - 20 C or lower

Supplier: Proteintech

Anti-BETA ADDUCIN Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Recombinant Protein, 1-331 amino acid, Format:Antigen affinity purification, Application: ELISA, WB, Recommended Storage: - 20 C or lower

Supplier: Proteintech

Transactivation response (TAR) DNA-binding protein of 43 kDa (also known as TARDBP or TDP-43) was first isolated as a transcriptional inactivator binding to the TAR DNA element of the HIV-1 virus. Neumann et al. (2006) found that a hyperphosphorylated, ubiquitinated, and cleaved form of TARDBP, known as pathologic TDP-43, is the major component of the tau-negative and ubiquitin-positive inclusions that characterize amyotrophic lateral sclerosis (ALS) and the most common pathological subtype of frontotemporal lobar degeneration (FTLD-U). 22309-1-AP is a rabbit polyclonal antibody recognizing TDP-43 only when phosphorylated at 409/410. This antibody detects phosphorylated forms of TDP-43 as well as the cleavage product of 20-30 kDa. Immunohistochemical analyses using this antibody only stain the insoluble inclusions in pathologic tissues without normal diffuse nuclear staining.

Supplier: Proteintech

Homeobox protein Nkx-2.1 (NKX2-1), also named Thyroid nuclear factor 1,Thyroid transcription factor 1(TTF1). It is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Defects in NKX2-1 are the cause of benign hereditary chorea (BHC), choreoathetosis, hypothyroidism, and neonatal respiratory distress (CHNRD).

Supplier: Proteintech

RAS (derived from 'RAt Sarcoma' virus) gene family includes KRAS, HRAS, and NRAS. These genes encode very similar 21KD proteins and are homologs of rodent sarcoma virus genes that have transforming abilities. KRAS has two isoforms, a and b. This antibody is specific for KRASA.

Supplier: Proteintech

Anti-MYH9(Polyclonal) Antibody, Host Species: Rabbit, Cross Reactivity: Human, Immunogen: Peptide, Peptide with Sequence CSDEEVDGKADGADAK AAE, Format:Antigen affinity purification, Application: ELISA, WB, IHC, IF, Recommended Storage: - 20 C or lower

Supplier: Proteintech

Anti-PYGL(Polyclonal) Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Recombinant Protein, 499-846 amino acid, Format:Antigen affinity purification, Application: ELISA, WB, IHC, Recommended Storage: - 20 C or lower

Supplier: Proteintech

MME is also names as neprilysin,CALLA,NEP,SFE,CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas.

Supplier: Proteintech

CPOX(Coproporphyrinogen-III oxidase, mitochondrial) is also named as CPO and CPX. Human CPO is a 76 kDa protein that is active as a homodimer in the mitochondrial intermembrane pace.Mutations in human CPO gene predict the clinical outcome of the disease, with either hepatic hereditary coproporphyria or hematological manifestations of erythropoietic harderoporphyria.CPOX has a transit peptide of 110 aa and the chain contains 344 aa.

Supplier: Proteintech

APEX1, also named as APE, APE1, HAP1 and REF-1, belongs to the DNA repair enzymes AP/ExoA family. It is a multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 are in DNA repair and redox regulation of transcriptional factors. APEX nuclease is a DNA repair enzyme having apurinic/apyrimidinic (AP) endonuclease, 3-prime,5-prime-exonuclease, DNA 3-prime repair diesterase, and DNA 3-prime-phosphatase activities. On the other hand, APEX1 also exerts reversible nuclear redox activity to regulate DNA binding affinity and transcriptional activity of transcriptional factors by controlling the redox status of their DNA-binding domain, such as the FOS/JUN AP-1 complex after exposure to IR. APEX1 is involved in calcium-dependent down-regulation of parathyroid hormone (PTH) expression by binding to negative calcium response elements (nCaREs). When acetylated at Lys-6 and Lys-7, APEX1 stimulates the YBX1-mediated MDR1 promoter activity, leading to drug resistance. It also acts as an endoribonuclease involved in the control of single-stranded RNA metabolism. It plays a role in regulating MYC mRNA turnover by preferentially cleaving in between UA and CA dinucleotides of the MYC coding region determinant (CRD). In association with NMD1, APEX1 plays a role in the rRNA quality control process during cell cycle progression. 10203-1-AP is a rabbit polyclonal antibody raised against full length APE1 of human origin.

Supplier: Proteintech

The vacuolar-type H(+)-ATPase (V-ATPase) is responsible for the acidification of endosomes, lysosomes, and other intracellular organelles. It is also involved in hydrogen ion transport across the plasma membrane into the extracellular space. The V-ATPase is a multisubunit complex with cytosolic and transmembrane domains. The cytosolic catalytic domain consists of 3 A subunits and 3 B subunits, which bind and hydrolyze ATP, as well as regulatory accessory subunits.ATP6V1A is V-type proton ATPase catalytic subunit A.This antibody is specific to ATP6V1A.

Supplier: Proteintech

The CD13 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human CD13. This antibody recognizes human antigen. The CD13 antibody has been validated for the following applications: ELISA, WB, IHC analysis.

Supplier: Proteintech

The BMP3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human BMP3. This antibody recognizes human antigen. The BMP3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.

Supplier: Proteintech

The TACC3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TACC3. This antibody recognizes human antigen. The TACC3 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.

Supplier: Proteintech

The PKC delta antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PKC delta. This antibody recognizes human,mouse,rat antigen. The PKC delta antibody has been validated for the following applications: ELISA, WB analysis.

Supplier: Proteintech

The TRPT1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TRPT1. This antibody recognizes human,mouse,rat antigen. The TRPT1 antibody has been validated for the following applications: ELISA, IHC analysis.

Supplier: Proteintech

The CNDP1 Antibody from Proteintech is a rabbit polyclonal Antibody to a fusion protein of human CNDP1. This Antibody recognizes human,mouse,rat Antigen. The CNDP1 Antibody has been validated for the following applications: ELISA, WB analysis.

Supplier: Proteintech

The APOM antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human APOM. This antibody recognizes human,mouse,rat antigen. The APOM antibody has been validated for the following applications: ELISA, WB, IHC analysis.

Supplier: Proteintech

The ACTR1B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ACTR1B. This antibody recognizes human,mouse,rat antigen. The ACTR1B antibody has been validated for the following applications: ELISA, IHC, IF, WB analysis.

Supplier: Proteintech

The SMO antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SMO. This antibody recognizes human antigen. The SMO antibody has been validated for the following applications: ELISA, IHC analysis.

Supplier: Proteintech

The CDH10-specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human CDH10-specific. This antibody recognizes human,mouse,rat antigen. The CDH10-specific antibody has been validated for the following applications: ELISA, WB analysis.

Supplier: Proteintech

The USF1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human USF1. This antibody recognizes human antigen. The USF1 antibody has been validated for the following applications: ELISA, WB analysis.

Supplier: Proteintech

The ATG2A antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ATG2A. This antibody recognizes human antigen. The ATG2A antibody has been validated for the following applications: ELISA, IHC, WB analysis.

Supplier: Proteintech

The IFIT1L antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human IFIT1L. This antibody recognizes human, rat, mouse antigen. The IFIT1L antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.

Supplier: Proteintech

The FERMT1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human FERMT1. This antibody recognizes human, mouse antigen. The FERMT1 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.