"Prosci"

Supplier: Prosci

Anti-NEK9 Rabbit Polyclonal Antibody

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Anti-Mouse Monoclonal Antibody [clone: [21-1A4]] (PE (Phycoerythrin))

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JPH3 Antibody: Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain. In the CNS, both JPH3 and JPH4 are expressed throughout neural sites and contribute to the subsurface cistern formation in neurons. Mice lacking both JPH3 and JPH4 subtypes exhibit serious symptoms such as impaired learning and memory and are accompanied by abnormal nervous functions. A repeat expansion in JPH3 is associated with Huntington disease-like 2. At least two isoforms of JPH3 are known to exist.

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ZFYVE19 contains 1 FYVE-type zinc finger. A chromosomal aberration, translocation t (11;15) (q23;q14) with MLL/HRX, involving ZFYVE19 is associated with acute myeloblastic leukemia (AML).

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PITX1 is a member of the RIEG/PITX homeobox family, which is involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.

Supplier: Prosci

UPF1 is a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. UPF1 is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

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CROCCL2 belongs to the rootletin family. The exact functions of CROCCL2 remain unknown.

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Anti-Spike Protein Recombinant Antibody [clone: 2196] (Biotinylated)

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cardiac troponin T Peptide

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Human Recombinant IL-36-gamma Protein (Animal Free) (from E. coli)

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TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.

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Anti-CAST Rabbit Polyclonal Antibody

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Anti-SLC1A6 Rabbit Polyclonal Antibody

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Anti-IL18R1 Rabbit Polyclonal Antibody

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CD8a Antibody, monoclonal, Host: Rat, Species reactivity: mouse, Isotype: IgG2a, kappa, Clone: 53-6.7, Conjugate: PE-Cy5, Applications: Fluorescence-activated cell sorting

Supplier: Prosci

Polyclonal antibody DSCAM Host: Goat Target Species: human immunogen: DSCAM antibody was raised against a 15 amino acid synthetic peptide near the internal region of DSCAM. Application: ELISA, WB