42407 Results for: "Pifithrin-alpha+hydrobromide"

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Mouse TNNI2 (Troponin I Type 2 Fast Skeletal). The assay range is from 15.6 to 1000 pg/ml (Sandwich kit) with a sensitivity of 5.5 pg/ml. There is no detectable cross to reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human TNFR1 (Tumor Necrosis Factor Receptor 1). The assay range is from 15.6 to 1000 pg/ml (Sandwich kit) with a sensitivity of 6.5 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human UCRP (Ubiquitin Cross Reactive Protein). The assay range is from 31.2 to 2000 pg/ml (Sandwich kit) with a sensitivity of 12.4 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human GLP1 (Glucagon Like Peptide 1). The assay range is from 12.35 to 1000 pg/ml (Competitive kit) with a sensitivity of 4.92 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Antibodies.com

Mouse NRG1 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse NRG1 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Biotium

HCG-beta, Monoclonal antibody, Clone: HCGb/54+ HCGb/459, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF647, Immunogen: Recombinant hCG beta protein (HCGb/54 and HCGb/459), Synonyms: CG-beta; CGB3; CGB5; CGB7; CGB8, Application: IHC, Size: 100uL

Supplier: Bioss

Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).

Supplier: Bioss

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011].

Supplier: Prosci

May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

Supplier: Prosci

Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e. g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.

Supplier: Bioss

GCN1L1 is a 2,671 amino acid protein that is ubiquitously expressed and belongs to the GCN1 family. Functioning as a translation activator, GCN1L1 interacts with IMPACT to regulproteinate GCN2 kinase activity. GCN1L1 contains 24 HEAT repeats and is encoded by a gene that maps to human chromosome 12q24.23. Chromosome 12 encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

Supplier: Bioss

GCN1L1 is a 2,671 amino acid protein that is ubiquitously expressed and belongs to the GCN1 family. Functioning as a translation activator, GCN1L1 interacts with IMPACT to regulproteinate GCN2 kinase activity. GCN1L1 contains 24 HEAT repeats and is encoded by a gene that maps to human chromosome 12q24.23. Chromosome 12 encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

Supplier: Bioss

Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Supplier: Biogems

The BC96 monoclonal antibody specifically reacts with the 55 kDa type I transmembrane glycoprotein known as the interleukin-2 receptor α (IL-2R α, also known as CD25). CD25 is expressed by the early progenitors of T and B lymphocytes lineage, and by activated mature T and B lymphocytes. CD25 is a low affinity interleukin-2 receptor, but its association with the IL-2 receptor β chain (CD122) and the common γ chain (CD 132) results in a high affinity IL-2R complex. CD25 plays an important role in B and T cell proliferation, differentiation, and activation.

Supplier: Biotium

CD74 Monoclonal antibody, Clone: CLIP/1133, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Recombinant full-length human CD74 protein, Application: IF, Western, FC, Size: 500 uL

Supplier: Biotium

HLA-DRB, Monoclonal antibody, Clone: LN-3 + HLA-DRB/1067, Host: Mouse, Species reactivity: Human, Monkey, Isotype: IgG's, Conjugate: CF594, Immunogen: Activated human peripheral blood mononuclear cells (LN-3 & HLA-DRB/1067), Application: IF, IHC Western, Size: 100uL

Supplier: Bioss

Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.

Supplier: Cloud-Clone

Anti-Beta Actin (ACTB) Polyclonal Antibody, derived from recombinant ACTB, is reactive with Human/Mouse/Rat/Guinea pig/Rabbit/Dog/Pig/Bovine/Sheep/Horse/Chicken/Zebrafish.

Supplier: ABCAM INC CA

Anti-Collagen VI antibody [EPR17072] ab182744 is a rabbit monoclonal antibody that is used in Collagen VI western blotting, IHC and immunofluorescence. Suitable for human, mouse and rat samples. - Recombinant format for unrivaled batch-batch consistency: no need for same-lot requests - Antibody clone EPR17072 is the most widely used clone for Collagen VI on the market - Specificity confirmed with COL6A1 knockout cell line validation - Specificity and sensitivity confirmed in IHC with multi-tissue microarray (TMA) validation.

Supplier: Antibodies.com

Human Bradykinin ELISA kit is a competitive Enzyme-Linked Immunosorbent Assay (cELISA) designed for the in vitro quantitative determination of human Bradykinin in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Bioss

Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK8/JNK1. In turn, MAPK8/JNK1 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. Phosphorylates the replication licensing factor CDT1, inhibiting the interaction between CDT1 and the histone H4 acetylase HBO1 to replication origins. Loss of this interaction abrogates the acetylation required for replication initiation. Promotes stressed cell apoptosis by phosphorylating key regulatory factors including p53/TP53 and Yes-associates protein YAP1. In T-cells, MAPK8 and MAPK9 are required for polarized differentiation of T-helper cells into Th1 cells. Contributes to the survival of erythroid cells by phosphorylating the antagonist of cell death BAD upon EPO stimulation. Mediates starvation-induced BCL2 phosphorylation, BCL2 dissociation from BECN1, and thus activation of autophagy. Phosphorylates STMN2 and hence regulates microtubule dynamics, controlling neurite elongation in cortical neurons. In the developing brain, through its cytoplasmic activity on STMN2, negatively regulates the rate of exit from multipolar stage and of radial migration from the ventricular zone. Phosphorylates several other substrates including heat shock factor protein 4 (HSF4), the deacetylase SIRT1, ELK1, or the E3 ligase ITCH.

Supplier: Biotium

MHC II (HLA-DRA), Monoclonal antibody, Clone: 19-26.1, Host: Mouse, Species reactivity: Human, Monkey, Isotype: IgM, kappa, Conjugate: CF647, Immunogen: Spleen cells of a patient with hairy cell leukemia (Daudi cells), Application: Immunofluorescence, Flow, Size: 100uL

Supplier: Biotium

CD21 Monoclonal antibody, Clone: FR5A10, Host: Mouse, Conjugate: CF640R, Species reactivity: Human, Isotype: IgG3, kappa, Synonyms:CD21; Complement C3d receptor (C3DR); Complement Receptor type 2 (CR2); CVID7, Application: IF, IHC (frozen), FC, Size: 500 uL

Supplier: Biotium

CD21 Monoclonal antibody, Clone: FR5A10, Host: Mouse, Species reactivity: Human, Isotype: IgG3, kappa, Conjugate: CF488A, Immunogen: Raji cells, Synonyms: CD21, Complement C3d receptor (C3DR), Application: IF, IHC, FC, Size: 500 uL

Supplier: Prosci

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Supplier: Biotium

MHC II Monoclonal antibody, Clone: 169-1B5.2, Host: Mouse, Species reactivity: Human, Cow, Cat, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Human peripheral blood leukocytes, Application: Immunofluorescence, Flow cytometry, Size: 100uL

Supplier: Biotium

MHC II Monoclonal antibody, Clone: 169-1B5.2, Host: Mouse, Species Reactivity: Human, Cow, Cat, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Detects a monomorphic general framework determinant of HLA-DR Class II antigen, Application: IF, Fc, Size: 500ul

Supplier: Biotium

MHC II, Monoclonal antibody,Clone: 169-1B5.2, Host: Mouse, Species reactivity: Human, Cow, Cat, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Human peripheral blood leukocytes, Application: Immunofluorescence, Flow cytometry, Size: 500 ul

Supplier: Biotium

HCG-beta, Monoclonal antibody, Clone: HCGb/54, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF640R, Immunogen: Recombinant hCG beta protein (HCGb/54 and HCGb/459), Synonyms: CG-beta; CGB3; CGB5; CGB7; CGB8, Application: Immunofluorescence, Size: 100uL

Supplier: Cloud-Clone

This assay has high sensitivity and excellent specificity for detecting Human DDIT3 (DNA Damage Inducible Transcript 3). The assay range is from 0.312 to 20 ng/ml (Sandwich kit) with a sensitivity of 0.118 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.