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6346 results for "Peprotech"

6346 Results for: "Peprotech"

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Human Recombinant IL-5 (from E. coli)

Supplier: Peprotech

IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 are cross-species reactive. Recombinant Human IL-5 is a 26.5 kDa disulfide-linked homodimeric protein containing two 116 amino acid chains.

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Human Recombinant GDF-3 (from E. coli)

Supplier: Peprotech

GDF-3 is a member of the TGF-beta superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-beta family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia that characterizes Type 2 diabetes. Recombinant Human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains.

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Human Recombinant sRANK Ligand (from E. coli)

Supplier: Peprotech

RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic cell-membrane protein, which, by interacting with RANKL, augments the ability of dendritic cells. These dendritic cells then stimulate naive T-cell proliferation in a mixed lymphocyte reaction, promote the survival of RANK+ T-cells, and regulate T-cell-dependent immune response. RANKL, which is expressed in a variety of cells, including osteoblasts, fibroblasts, activated T-cells and bone marrow stromal cells, is also capable of interacting with a decoy receptor called OPG. Binding of soluble OPG to sRANKL inhibits osteoclastogenesis by interrupting the signaling between stromal cells and osteoclastic progenitor cells, thereby leading to excess accumulation of bone and cartilage. Human RANKL is reactive on murine cells. Recombinant Human sRANK Ligand is a 20.0 kDa polypeptide comprising the TNF-homologous region of RANKL (176 amino acid residues).

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Human Recombinant TECK (CCL25) (from E. coli)

Supplier: Peprotech

TECK is a CC chemokine, specifically expressed by thymic stromal cells, and signals through the CCR9 receptor. TECK is chemotactic towards activated macrophages, thymocytes and dendritic cells. Recombinant Human TECK (CCL25) is a 14.2 kDa protein containing 127 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

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Human;Mouse;Rat Recombinant GDF-11 (from E. coli)

Supplier: Peprotech

GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves the arrest of the progenitor cell cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggest that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same. Recombinant Human/Murine/Rat GDF-11 is a 25.0 kDa disulfide-linked homodimer containing two 109 amino acid polypeptide chains. It is highly homologous to myostatin/GDF-8, sharing 90% amino acid sequence identity.

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Anti-IgG Rabbit Polyclonal Antibody p16-INK-4a TAT

Supplier: Peprotech

p16-INK4a-TAT, Polyclonal antibody, Host: Rabbit, Species: Human, Immunogen: E.coli derived Recombinant Human p16-INK4a-TAT, Application: Sandwich ELISA, Western Blot, Purity: affinity chromatography, Size: 1MG

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Anti-IgG Rabbit Polyclonal Antibody LIGHT

Supplier: Peprotech

Light, Polyclonal antibody, Host: Rabbit, Species: Murine, Immunogen: E.coli derived Recombinant Murine LIGHT, Application: Sandwich ELISA, Western Blot, Purity: affinity chromatography, Size: 100UG

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Anti-IgG Rabbit Polyclonal Antibody sCD14

Supplier: Peprotech

sCD14, Polyclonal antibody, Host: Rabbit, Species: Human, Immunogen: HEK293 cells derived Recombinant Human sCD14, Application: Sandwich ELISA, Western Blot, Purity: affinity chromatography, Size: 1MG

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Anti-IgG Rabbit Polyclonal Antibody (Biotin) Resistin

Supplier: Peprotech

RESISTIN Polyclonal antibody, Host: Rabbit, Species reactivity: Human, Conjugate: Biotin, Immunogen: E.coli derived Recombinant Human Resistin, Formulation: Lyophilized, Purification: affinity chromatography, Application: Sandwich ELISA, WB, Size: 25 uG

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Rat Recombinant GDNF (from E. coli)

Supplier: Peprotech

GDNF is a disulfide-linked, homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFRalpha (alpha1-alpha4) receptors. GDNF specifically promotes dopamine uptake and survival, and morphological differentiation of midbrain neurons. Using a Parkinson's disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional rat GDNF ligand is a disulfide-linked homodimer consisting of two 15 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, including Cys-101, which is used for inter-chain disulfide bridging, and others that are involved in the intramolecular ring formation known as the cysteine-knot configuration. The calculated molecular weight of Recombinant Rat GDNF is 30.0 kDa.

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Human Recombinant PD-L1 (from CHO Cells)

Supplier: Peprotech

Recombinant Human PD-L1 Fc, Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses, Source: CHO cells, Determined by its ability to induce adhesion in T-cell enriched PBMC cultures, Synonyms: Programmed Death Ligand 1, PD-1, B7-H1, SLEB2, SLE1, Size: 20UG

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Anti-IL-36gamma (IL-1F9) Rabbit Polyclonal Antibody (Biotin)

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human IL-36γ (IL-1F9). Anti­Human IL-36γ (IL-1F9)­specific antibody was purified by affinity chromatography and then biotinylated.

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Human Recombinant B7-2 (from CHO cells)

Supplier: Peprotech

Recombinant Human B7-2 Fc, Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses, Source: CHO cells, Determined by its ability to inhibit alkaline phosphatase activity in differentiating MC3T3/E1 cells, Synonyms: B70, CD86, ETC1, Size: 250UG

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Anti-NT-3 Rabbit Polyclonal Antibody

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human NT-3. Anti­Human NT-3­specific antibody was purified by affinity chromatography employing an immobilized Human NT-3 matrix.

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Human Recombinant HPRG (from CHO cells)

Supplier: Peprotech

Human HPRG Recombinant Protein, Purity: >90%, Source: CHO cells, Biological Activity: Measured by its ability to support adhesion of Con-A activated MOLT-4 cells to the Recombinant Human HPRG-coated surface, Synonyms: H

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Mouse Recombinant IL-22 (from E. coli)

Supplier: Peprotech

Animal-Free Murine IL-22 Recombinant Protein, Purity: >98%, Source: E.coli, Biological Activity: By its ability to induce IL-10 secretion in COLO 205 (human colon carcinoma cells), Synonyms: Interleukin-

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Human Recombinant IL-17D (from E. coli)

Supplier: Peprotech

Recombinant Human Il-17D (Animal free), is a 40.5 kDa disulfide-linked homodimer of two 185 amino acid polypeptide chains, Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses, Source: E.coli, Cross Reactivity: Mouse, Synonyms: Interleukin-17D, Size: 5UG

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Rat TNF-α Standard TMB ELISA Development Kit, PeproTech

Supplier: Peprotech

PeproTech's Rat TNF-α ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant rat TNF-α in a sandwich ELISA format.

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Human;Mouse;Rat Recombinant Irisin (from CHO cells)

Supplier: Peprotech

Recombinant Human/Murine/Rat Irisin, Purity: Greater than 90% by SDS-PAGE, Source: CHO cells, Cross Reactivity: Human, Mouse, Rat, Synonyms: Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2, Size: 100UG

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Anti-G-CSF Mouse Monoclonal Antibody

Supplier: Peprotech

Monoclonal AntibodyProduced in BALB/c-mice immunized with highly pure Recombinant Human G-CSF. Anti­Human G-CSF­specific antibody was purified from cell culture by Protein A affinity chromatography.

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Anti-MCP-4 (CCL13) Rabbit Polyclonal Antibody

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human MCP-4 (CCL13). Anti­Human MCP-4 (CCL13)­specific antibody was purified by affinity chromatography employing an immobilized Human MCP-4 matrix.

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Anti-NAP-2 (CXCL7) Rabbit Polyclonal Antibody

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human NAP-2 (CXCL7). Anti­Human NAP-2 (CXCL7)­specific antibody was purified by affinity chromatography employing an immobilized Human NAP-2 matrix.

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Anti-PF-4 (CXCL4) Rabbit Polyclonal Antibody (Biotin)

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human PF-4 (CXCL4). Anti­Human PF-4 (CXCL4)­specific antibody was purified by affinity chromatography and then biotinylated.

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Anti-IGF-II Rabbit Polyclonal Antibody (Biotin)

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human IGF-II. Anti­Human IGF-II­specific antibody was purified by affinity chromatography and then biotinylated.

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Anti-IgG Rabbit Polyclonal Antibody (Biotin) IGF-II

Supplier: Peprotech

Human IGF-II, Animal Free, Polyclonal Antibody, Source: Rabbit, Preparation: purified by affinity chromatography and then biotinylated, Immunogen:E.coli derived Recombinant Human IGF-II, Application:ELISA, Western Blot, 50ug

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Anti-Flt3-Ligand Rabbit Polyclonal Antibody (Biotin)

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human Flt3-Ligand. Anti­Human Flt3-Ligand­specific antibody was purified by affinity chromatography and then biotinylated.

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Anti-Flt3-Ligand Rabbit Polyclonal Antibody

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human Flt3-Ligand. Anti­Human Flt3-Ligand­specific antibody was purified by affinity chromatography employing an immobilized Human Flt3-Ligand matrix.

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Anti-EGF Rabbit Polyclonal Antibody

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human EGF. Anti­Human EGF­specific antibody was purified by affinity chromatography employing an immobilized Human EGF matrix.

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Human Recombinant BD1 (from E. coli)

Supplier: Peprotech

Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Human BD-1 is a 3.9 kDa protein containing 36 amino acid residues.

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Human Recombinant sTNF (from E. coli)

Supplier: Peprotech

TNFRI belongs to the TNFR superfamily of transmembrane proteins, and is expressed in most cell types. Binding of either TNF-α or TNF-β to TNFRI initiates a signal transduction pathway that results in the activation of the transduction factor NF-κB, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells induce apoptosis. Soluble TNF Receptor I (sTNFRI) is capable of inhibiting TNF-α and TNF-β activities by acting as a decoy receptor that serves as a sink for the TNF ligands. The human TNFRI gene encodes for a 455 amino acid type I transmembrane protein, which contains a 21 amino acid signal sequence, a 190 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 221 amino acid cytoplasmic domain. Recombinant Human sTNF Receptor Type I is an 18.3 kDa protein (162 amino acid residues) comprising the cysteine-rich, ligand-binding portion of the extracellular domain of the TNFRI protein.

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