6346 Results for: "Peprotech"

Supplier: Peprotech

Animal-Free Murine IL-22 Recombinant Protein, Purity: >98%, Source: E.coli, Biological Activity: By its ability to induce IL-10 secretion in COLO 205 (human colon carcinoma cells), Synonyms: Interleukin-

Supplier: Peprotech

Recombinant Human B7-2 Fc, Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses, Source: CHO cells, Determined by its ability to inhibit alkaline phosphatase activity in differentiating MC3T3/E1 cells, Synonyms: B70, CD86, ETC1, Size: 100UG

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human IL-36γ (IL-1F9). Anti­Human IL-36γ (IL-1F9)­specific antibody was purified by affinity chromatography and then biotinylated.

Supplier: Peprotech

Recombinant Human PD-L1 Fc, Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses, Source: CHO cells, Determined by its ability to induce adhesion in T-cell enriched PBMC cultures, Synonyms: Programmed Death Ligand 1, PD-1, B7-H1, SLEB2, SLE1, Size: 500UG

Supplier: Peprotech

GDNF is a disulfide-linked, homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFRalpha (alpha1-alpha4) receptors. GDNF specifically promotes dopamine uptake and survival, and morphological differentiation of midbrain neurons. Using a Parkinson's disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional rat GDNF ligand is a disulfide-linked homodimer consisting of two 15 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, including Cys-101, which is used for inter-chain disulfide bridging, and others that are involved in the intramolecular ring formation known as the cysteine-knot configuration. The calculated molecular weight of Recombinant Rat GDNF is 30.0 kDa.

Supplier: Peprotech

Recombinant Human Il-17D (Animal free), is a 40.5 kDa disulfide-linked homodimer of two 185 amino acid polypeptide chains, Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses, Source: E.coli, Cross Reactivity: Mouse, Synonyms: Interleukin-17D, Size: 5UG

Supplier: Peprotech

PeproTech's Rat TNF-α ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant rat TNF-α in a sandwich ELISA format.

Supplier: Peprotech

Human HPRG Recombinant Protein, Purity: >90%, Source: CHO cells, Biological Activity: Measured by its ability to support adhesion of Con-A activated MOLT-4 cells to the Recombinant Human HPRG-coated surface, Synonyms: H

Supplier: Peprotech

Recombinant Human/Murine/Rat Irisin, Purity: Greater than 90% by SDS-PAGE, Source: CHO cells, Cross Reactivity: Human, Mouse, Rat, Synonyms: Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2, Size: 100UG

Supplier: Peprotech

Monoclonal AntibodyProduced in BALB/c-mice immunized with highly pure Recombinant Human G-CSF. Anti­Human G-CSF­specific antibody was purified from cell culture by Protein A affinity chromatography.

Supplier: Peprotech

GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves the arrest of the progenitor cell cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggest that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same. Recombinant Human/Murine/Rat GDF-11 is a 25.0 kDa disulfide-linked homodimer containing two 109 amino acid polypeptide chains. It is highly homologous to myostatin/GDF-8, sharing 90% amino acid sequence identity.

Supplier: Peprotech

IL-2 SRECEPTOR ALPHA Polyclonal antibody, Host: Rabbit, Species reactivity: Human, Immunogen: CHO cells derived Recombinant Human IL-2 Receptor A, Formulation: Lyophilized, Application: Sandwich ELISA, Western Blot, Size: 100 uG

Supplier: Peprotech

RESISTIN Polyclonal antibody, Host: Rabbit, Species reactivity: Human, Conjugate: Biotin, Immunogen: E.coli derived Recombinant Human Resistin, Formulation: Lyophilized, Purification: affinity chromatography, Application: Sandwich ELISA, WB, Size: 50 uG

Supplier: Peprotech

IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 are cross-species reactive. Recombinant Human IL-5 is a 26.5 kDa disulfide-linked homodimeric protein containing two 116 amino acid chains.

Supplier: Peprotech

p16-INK4a-TAT, Polyclonal antibody, Host: Rabbit, Species: Human, Immunogen: E.coli derived Recombinant Human p16-INK4a-TAT, Application: Sandwich ELISA, Western Blot, Purity: affinity chromatography, Size: 1MG

Supplier: Peprotech

Light, Polyclonal antibody, Host: Rabbit, Species: Murine, Immunogen: E.coli derived Recombinant Murine LIGHT, Application: Sandwich ELISA, Western Blot, Purity: affinity chromatography, Size: 100UG

Supplier: Peprotech

sCD14, Polyclonal antibody, Host: Rabbit, Species: Human, Immunogen: HEK293 cells derived Recombinant Human sCD14, Application: Sandwich ELISA, Western Blot, Purity: affinity chromatography, Size: 1MG

Supplier: Peprotech

Serum amyloid A proteins (SAA) represents a family of apolipoproteins that circulates in association with high-density lipoproteins (HDL). The level of Apo-SAA, normally 1-5 ug/ml in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL apolipoprotein. The human SAA gene codes for a 122 amino acid nonglycosylated polypeptide, which contains an 18 amino acid N-terminal sequence. Recombinant Human Apo-SAA1 is an 11.7 kDa protein containing 105 amino acid residues.

Supplier: Peprotech

Recombinant Human Leptin Receptor, Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses, Source: CHO cellshighly expressed in hypothalamic neurons, T-cells, and the vascular endometrium, Synonyms: LEP-R, HuB219, Obesity Protein Receptor, Size: 500UG

Supplier: Peprotech

Recombinant Human sIL-6 Receptor A, Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses, Source: CHO cells, Determined by its ability to intensify the IL-6 induced growth inhibition, Synonyms: soluble IL-6 receptor alpha, CD126, Size: 500UG

Supplier: Peprotech

TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of 6-phosphofructose-1 kinase, the rate limiting enzyme of glycolysis. By lowering the intracellular level of F-2-6-BP, TIGAR expression leads to increased glucose processing via the pentose phosphate pathway, the major cellular source for NADPH. Recombinant Human TIGAR expressed in

Supplier: Peprotech

Uteroglobin, which is a member of the Secretoglobin superfamily and is also known as Clara cell phospholipid-binding protein, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. The small, non-glycosylated protein named for its high levels of expression in pre-implantation embryos, where it exhibits growth stimulatory effects, is produced and secreted by the non-ciliated, non-mucous Clara cells predominant in the epithelial surfaces of pulmonary airways, as well as other non-ciliated epithelia. Members of the Secretoglobin superfamily demonstrate a high level of structural conservation and are characterized as small, secretory homo- or heterodimers. In addition to sequestering pro-inflammatory mediators and carcinogens, Uteroglobin has been implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation. Recombinant Human Uteroglobin is a 16.1 kDa homodimeric protein consisting of 142 amino acid residues.

Supplier: Peprotech

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Murine MIP-2 (CXCL2) is a 7.8 kDa protein consisting of 73 amino acids, including the ‘ELR’ motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.

Supplier: Peprotech

Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The four known members of this family, resistin, RELMα, RELMβ, and RELMγ, share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that resistin expression is severely suppressed in obesity, and that it may act as a feedback regulator of Adipogenesis. Recombinant Murine Resistin is a 20.2 kDa, disulfide-linked, homodimeric protein composed of two identical 94 amino acid chains linked by a single disulfide bond.

Supplier: Peprotech

FGF-9 is a heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-9 targets glial cells, astrocytes cells and other cells that express the FGFR 1c, 2c, 3b, 3c, and 4. Recombinant Murine FGF-9 is a 23.3 kDa protein containing 206 amino acid residues.

Supplier: Peprotech

Noggin belongs to a group of diffusible proteins that bind to ligands of the TGF-β family, and regulate their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP-4 antagonist whose action was critical for proper formation of the head and other dorsal structures. Consequently, noggin has been shown to modulate the activities of other BMPs including BMP-2,-7,-13, and -14. Targeted deletion of noggin in mice results in prenatal death, and a recessive phenotype displaying a severely malformed skeletal system. Conversely, transgenic mice over-expressing noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis. Recombinant Murine Noggin is a 46.4 kDa disulfide-linked homodimer consisting of two 206 amino acid polypeptide chains.

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human sCD22. Anti­Human sCD22­specific antibody was purified by affinity chromatography and then biotinylated.

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human Nanog. Anti­Human Nanog­specific antibody was purified by affinity chromatography and then biotinylated.

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human IGF-BP5. Anti­Human IGF-BP5­specific antibody was purified by affinity chromatography employing an immobilized Human IGF-BP5 matrix.

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human IGF-BP1. Anti­Human IGF-BP1­specific antibody was purified by affinity chromatography and then biotinylated.