36277 Results for: "PICKERING+LABS+MS&pageNo=12"

Supplier: Bioss

May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.

Supplier: Antyila Scientific

Reduce maintenance time with self-diagnostic function.

Supplier: Justrite

This Single Cylinder Hand Truck with Hoist Ring provides safety when moving and storing of gas cylinders.

Supplier: Biotium

Calgranulin B / MRP-8/-14 Monoclonal antibody, Clone: MAC387, Host: Mouse, Species reactivity: Monkey, Goat, Baboon, Pig, Dog, Cow, Cat, Rat, Human, Isotype: IgG1, K, Conjugate: CF488A, Synonyms: MAC 387 / S100A8/A9 / Macrophage Ag, Size: 100uL

Supplier: Promega Corporation

The HaloTag Technology enables covalent protein labeling and immobilization in vivo and in vitro.

Supplier: Biotium

Calgranulin B / MRP-8/-14 Monoclonal antibody, Clone: MAC387, Host: Mouse, Species reactivity: Monkey, Goat, Baboon, Pig, Dog, Cow, Cat, Rat, Human, Isotype: IgG1, K, Conjugate: CF568, Synonyms: MAC 387 / S100A8/A9 / Macrophage Ag, Size: 500 uL

Supplier: Huber

Refrigeration bath circulators are suitable for controlling the temperature of externally connected applications and thermoregulation of objects directly in the thermostat bath

Supplier: Bulldog Bio

A reverse transcriptase engineered to deliver phenomenal results.

Supplier: Eppendorf

Eppendorf Deepwell plates 96-well, 500 µl offer efficient sample handling with features like OptiTrack® matrix for rapid identification and g-Safe® technology for stability during centrifugation. SafeCode variants provide secure three-level coding, including error correction for reliable identification, ensuring flexibility and accuracy in experimental workflows.

Supplier: Bioss

FAM84A is a 292 amino acid protein that belongs to the FAM84 family of proteins. Predominantly expressed in testis, FAM84A shares 44% amino acid identity with the related protein FAM84B. FAM84A localizes to a subcellular membrane region where there is no contact between neighboring cells and is believed to play a role in cell morphology and motility. More specifically, the expression of FAM84A increases cell motility. Two FAM84A isoforms are expressed due to alternative splicing events. Isoform 2 can be phosphorylated on various serine residues and this phosphorylation is associated with cellular morphology. FAM84A is upregulated in colorectal cancer, lung cancer, pancreatic cancer, cholangiocarcinoma and bladder cancer tissues. Via its ability to increase cell motility, FAM84A may contribute to the invasion and metastasis of cancer cells.

Supplier: Bioss

Syntaxin 13 is an integral membrane protein that belongs to the t-SNARE family, a group of proteins involved in protein transport. Confocal immunofluoresence and electron microscopy studies have shown that syntaxin 13 is primarily localized to tubular early and recycling endosomes, where it colocalizes with transferrin receptor, and it is also localized in endosomal vacuoles. Syntaxin 13 has been found to be expressed in all tissues, with higher levels of the protein found in brain, lung, spleen, thymus and testes. Immunoprecipitation studies show that syntaxin 13 complexes with beta-SNAP, VAMP2/3, and SNAP25. The binding of this complex to alpha-SNAP and NSF is terminated in the presence of ATP. These results suggest that syntaxin 13 is a SNARE protein which mediates the recycling protein flow through tubulo vesicular recycling endosomes.

Supplier: Labconco

ClassMate™ laboratory hoods are designed to meet the needs of instructional laboratories.

Supplier: Rockland Immunochemical

KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK12 is expressed mainly in the brain and lung, but also observed in the kidneys, heart and skeletal muscle. KCNK12 is closely related to KCNK13 (58% identity at the amino acid level), but could not yet been functionally expressed in vitro and may require other proteins to become active.

Supplier: Promega Corporation

Maxwell RSC Standard Warranty.

Supplier: Prosci

Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.

Supplier: Molecular Devices

This UV-visible absorbance microplate reader provides ultrafast, full spectral range detection for cuvettes, 96-well, and 384-well microplates, with the only temperature-independent method for pathlength correction.

Supplier: WORLD PRECISION INSTRUMENTS LLC

Aladdin High Pressure Single Syringe Pump is often used in research where precise, controlled delivery of fluids at elevated pressures is required. High-pressure syringe pumps can be used in chemical synthesis processes requiring precise control over the addition of reagents. This is especially important in reactions that occur under high pressures, such as certain types of catalytic reactions or polymerization processes.

Supplier: Avantor Performance Materials

US sourced amino acids

Supplier: United Product & Instrument

The 1100RS Visible Spectrophotometer features an accurate 10nm bandpass model and is designed for use with ¹/₂" (13 mm) round tubes or 10mm square cuvettes and is perfect for most laboratory/classroom applications. An adapter is supplied at no additional charge for 10 mm square optical glass cuvettes. The high quality silicon photodiode detector and 1200 lines/mm grating assures high performance. Auto zero function, one-touch blanking and built-in, automatic filters allow for easy operation. The large digital display allows for quick and easy readings. This visible spectrophotometer works with optional Windows® based software for easy data collection and application expansion to Standard Curve and Kinetics, Abs. and %T and Concentration, etc. Data can be easily exported to Microsoft Excel® for further processing and analysis. The software is designed for Windows based PCs using Windows® 2000, ME, or XP. A USB and RS-232 port is available on this spectrophotometer as well as Absorbance, Transmittance, Concentration (C) and Factor (F) modes. Each mode can be quickly selected with the touch of a button.

Supplier: Cell Systems

Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.

Supplier: Bioss

FAM84A is a 292 amino acid protein that belongs to the FAM84 family of proteins. Predominantly expressed in testis, FAM84A shares 44% amino acid identity with the related protein FAM84B. FAM84A localizes to a subcellular membrane region where there is no contact between neighboring cells and is believed to play a role in cell morphology and motility. More specifically, the expression of FAM84A increases cell motility. Two FAM84A isoforms are expressed due to alternative splicing events. Isoform 2 can be phosphorylated on various serine residues and this phosphorylation is associated with cellular morphology. FAM84A is upregulated in colorectal cancer, lung cancer, pancreatic cancer, cholangiocarcinoma and bladder cancer tissues. Via its ability to increase cell motility, FAM84A may contribute to the invasion and metastasis of cancer cells.

Supplier: Prosci

ZIP12 Antibody: The zinc transporter ZIP12, also known as SLC39A12, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP12 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Increased levels of ZIP12 have been observed during acute inflammation in the airway and asthma, suggesting that it may be promote increased zinc uptake, as this can reduce inflammation. The zinc content in brains in individuals with schizophrenia is lower than in individuals with other cerebral diseases, and mutations in ZIP12 have been observed in a small group of schizophrenic patients, suggesting that ZIP12 may play a role in this disease.

Supplier: Fujifilm Irvine Scientific

Interleukin 13 (IL-13) is a cytokine secreted from type 2 T helper (Th2) cells. IL-13 has overlapping functions with interleukin 4 (IL-4), including the induction of immunoglobulin E (IgE) secretion from B cells, and the inhibition of interleukin 1 beta (IL-1β), tumor necrosis factor alpha (TNFα), interleukin 8 (IL-8), and interleukin 6 (IL-6) inflammatory cytokine expression. IL-13 also regulates immune cell inflammation in response to the pathophysiological changes of surrounding non-immune cells. The IL-13 receptor consists of the IL-4Ra and IL-13Ra1 subunits. IL-13 can also bind the IL-13Ra2 receptor with high affinity. IL-13 functions are mediated through the JAK/STAT signaling pathway. Human and mouse IL-13 are cross-reactive.

Supplier: Promega Corporation

Maxwell RSC Standard Warranty.

Supplier: Hamilton

Hamilton Company offers one of the most comprehensive selections of chromatography columns in the industry.

Supplier: Cell Systems

Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.

Supplier: Janitorial Supplies

Next generation ready-to-use disinfectant cleaner formulated with patented hydrogen peroxide technology (AHP®) to deliver fast, effective cleaning performance. Contains no phosphates, quat or phenols. Cleans, disinfects and deodorizes in one labor-saving step. It is a one minute bactericidal, fungicidal, tuberculocidal and 10 sec non-food contact sanitizer. Disinfects viruses and is a soft surface sanitizer, both in 30 seconds. Kills MRSA, Norovirus, RSV and Adenovirus. Meets bloodborne pathogen standards for decontaminating surfaces soiled with blood and body fluids. Destroys allergens and kills germs, while cleaning hard, nonporous surfaces; removes allergens like pet dander, cockroach matter, dust mite debris, and pollen particles.

Supplier: Spectrum Chemical Mfg. Corp.

Copper Sulfate, Pentahydrate, Granular, FCC is used as a fungicide, algaecide and feed supplement. Find a high quality inventory of Copper Copper Sulfate, Pentahydrate, Granular, FCC. Approved by the Food Chemical Codex, it is used as a fungicide, algaecide, and feed supplement, and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

Supplier: Brady Worldwide

High-performance 3" core label printing the way you never thought possible. Get 40-second part changeovers with no adjustments, no trial-and-error print tests and no wasted labels. LabelSense™ Technology allows the printer, Brady® i75-Series materials and Brady® software to communicate; automating and eliminating tedious adjustments and label-wasting tasks.

Supplier: Promega Corporation

Upon purchase, the Maxwell CSC Instrument will be covered by a 1-year Premier Warranty, which covers all parts, labor and shipping to and from our depot repair location plus your choice of a loaner instrument or a visit by a repair technician.