"Other Essentials"

Supplier: Rockland Immunochemical

Human Interleukin-6 AccuSignal ELISA Kit

Supplier: FG CLEAN WIPES TE

These cleanroom wipes combine the versatility of a polyester/cellulose substrate with added strength, softness, and enhanced cleanliness. A special treatment further reduces ions, NVRs, and particulates, creating the highest level of cleanliness for a lint-free cleanroom wipe in its class.

Supplier: Veltek Associates

Steri-Perox® wipes leave no residue and are used for both aseptic and non-aseptic wipe downs of filling and packaging machinery, stainless steel surfaces, Lexan, polycarbonate, glass, and any critical surfaces that require cleaning.

Supplier: Rockland Immunochemical

Human TGFBR3 AccuSignal ELISA Kit

Supplier: Rockland Immunochemical

Mouse Interleukin-6 AccuSignal ELISA Kit

Supplier: Rockland Immunochemical

Human Interleukin-12(p70) AccuSignal ELISA Kit

Supplier: MP Biomedicals

Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.
Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis.
Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.

Supplier: MP Biomedicals

Cetyltrimethylammonium bromide is a phase transfer catalyst ideal for the precipitation of DNA. Hexadecyltrimethylammonium bromide is a bactericidal, cationic detergent. Its activity is neutralized by soaps and anionic detergents (i.e., SDS). Trimethylammonium bromide compounds form insoluble complexes with SDS. It is active at alkaline pH against both Gram positive and Gram negative organisms.

Supplier: Rockland Immunochemical

Human PECAM-1 - CD31 AccuSignal ELISA Kit

Supplier: Rockland Immunochemical

Mouse Interleukin-12(p70) AccuSignal ELISA Kit

Supplier: Rockland Immunochemical

Human GM-CSF AccuSignal ELISA Kit

Supplier: Rockland Immunochemical

Rat GM-CSF AccuSignal ELISA Kit

Supplier: Chem-Impex International

Boc-L-trans-4-hydroxyproline is a valuable amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a tert-butoxycarbonyl (Boc) protecting group, which enhances its stability and solubility, making it an ideal choice for various applications in organic synthesis. Its unique structure allows for the incorporation of hydroxyl groups into peptides, which can significantly influence the biological activity and stability of the resulting compounds. Researchers often employ Boc-L-trans-4-hydroxyproline in the development of bioactive peptides, particularly in the fields of drug discovery and development, where modifications to peptide structure can lead to improved therapeutic profiles.

Supplier: MP Biomedicals

A vitamin/enzyme cofactor found in milk, eggs, malted barley, liver, kidney, heart, leafy vegetables. Richest natural source is yeast. Occurs in the free form only in the retina of the eye, in whey, and in urine; bioactive forms occurring in tissues and cells are riboflavin monophosphate and flavine-adenine dinucleotide. Used as a photoinitiator for polymerization of polyacrylamide gels. It forms free radicals in aqueous solution in the presence of light. Riboflavin photodecomposes to leucoflavin. No free radicals are formed in the absence of oxygen but traces of oxygen allows for leucoflavin to reoxidize with free-radical generation. The catalysts TEMED or DMAPN are commonly added to speed up the free radical formation. The free radicals will cause acrylamide and bis-acrylamide to polymerize to form a gel matrix which can be used for electrophoresis. Riboflavin is commonly used in the stacking gel for non-denaturing polyacrylamide electrophoresis because native proteins can be senstive to persulfate ions from ammonium persulfate. Another advantage of riboflavin over ammonium persulfate is that it will not start polymerization until the gel is illuminated. Riboflavin causes less denaturing than other initiators. Gel strength can be improved when used with PTO (Pyrithione). Soluble in 0.1 M Sodium Hydroxide (50 mg/ml - clear, yellowish-orange solution); only slightly soluble in water.

Supplier: MP Biomedicals

Storage: Store at room temperature (15-30 °C)
L-Lysine monohydrochloride is widely used as nutritional supplements in food and beverage industries. It can also be used in animal feed as source of L-Lysine. L-Lysine Monohydrochloride can be used in a wide variety of industries including: food production, beverage, pharmaceutical, agriculture/animal feed, and various other industries.
L-Lysine monohydrochloride is a key amino acid in calcium absorption.

Supplier: VWR International

VWR® Basic nylon bouffant caps provide lightweight, breathable head coverage for controlled environments. Made from durable nylon, these caps are designed to minimize contamination by keeping hair securely contained. The non-linting material helps maintain cleanroom integrity, while the elastic closure ensures a comfortable, secure fit for various head sizes.