48 Results for: "List Biological Laboratories, Inc."
Pasteurella Multocida Toxin, List Biological Laboratories
Supplier: List Biological Laboratories, Inc.
Pasteurella multocida toxin is produced by some strains of Pasteurella multocida, a small gram-negative coccobacillus that is pathogenic for many species of animals
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Shiga Toxin, List Biological
Supplier: List Biological Laboratories, Inc.
Shiga toxin is a group of related toxins produced by Shigella dysenteriae and enterohemorrhagic Escherichia coli (EHEC)
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Cholera Toxins, List Biological Laboratories
Supplier: List Biological Laboratories, Inc.
Produced by Vibrio cholerae, cholera toxin (CT) is a multimeric enterotoxin that transfers ADP-ribose to a G protein, locking adenylate cyclase in an 'on' position
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Diphtheria Toxin and CRM, List Biological Laboratories
Supplier: List Biological Laboratories, Inc.
Corynebacterium diphtheriae is a Gram-positive bacterium which infects epithelial cells of the upper respiratory tract and produces diphtheria toxin
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Botulinum Toxins, List Biological Laboratories
Supplier: List Biological Laboratories, Inc.
Clostridium botulinum neurotoxins (BoNT) are among the most toxic substances known to man
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Pertussis Toxin and Virulence Factors, List Biological
Supplier: List Biological Laboratories, Inc.
Pertussis toxin (PT), a virulence factor produced by Bordetella pertussis, is a multi-subunit toxin which binds to most cultured mammalian cells and targets specific G protein, inhibiting the ability of the G protein to function in signaling pathways
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Anthrax Toxins, List Biological Laboratories
Supplier: List Biological Laboratories, Inc.
Bacillus anthracis is the etiological agent of anthrax
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Tetanus Toxins, List Biological Laboratories
Supplier: List Biological Laboratories, Inc.
Tetanus toxin is a potent neurotoxin that is taken up by presynaptic terminals at the neuromuscular junction, travels retrogradely within motor neurons and is transported transsynaptically to spinal cord interneurons
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Fret Peptides, Native Substrates and Receptors, List Biological
Supplier: List Biological Laboratories, Inc.
The potent toxicity of both the botulinum neurotoxins and anthrax lethal toxin is due to a zinc-dependent proteolytic activity associated with the toxins. Measurement of this enzymatic activity provides for both a potentially sensitive and direct means for detection of the toxin, and a method for identifying potential toxin inhibitors using high throughput screening. A highly efficient approach for monitoring enzymatic activity is based on the use of fluorescence resonance energy transfer (FRET) substrates. These fluorogenic peptides contain a donor fluorescent group at one end and a suitable chromogenic acceptor group at the other. The fluorescence is quenched initially by intramolecular energy transfer between the donor/acceptor pair. Cleavage of the FRET substrate by the appropriate enzyme releases the fluorophore and full fluorescence is restored. The increase in fluorescence intensity is directly proportional to the amount of enzyme present. Enzymatic activity can be monitored continuously by recording the increase in fluorescence intensity with time. The change in the relative fluorescence units (RFU) as cleavage occurs can be converted to nmoles of cleaved substrate from a standard curve generated using a Calibration Peptide which is the cleaved substrate containing only the N-terminally attached fluorophore. For Botulinum neurotoxin type A, a Control FRET peptide substrate that is not cleaved by the neurotoxin but contains all remaining non-specific sites in the sequence can be used to screen background cleavage of the substrate that can occur in complex matrices.
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Anti-Lethal Factor from Bacillus anthracis Chicken Polyclonal Antibody (Biotin)
Supplier: List Biological Laboratories, Inc.
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Lipopolysaccharides (LPS) and Related Products, List Biological Laboratories
Supplier: List Biological Laboratories, Inc.
Bacterial lipopolysaccharides have long been recognized as the active component of gram negative bacterial endotoxins
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Anti-Exotoxin A Goat Polyclonal Antibody
Supplier: List Biological Laboratories, Inc.
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C. difficle Toxins, List Biological
Supplier: List Biological Laboratories, Inc.
A major nosocomial pathogen, Clostridium difficile causes antibiotic-associated colitis and intestinal inflammatory disease, together called CDI
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Anti-CTB Goat Polyclonal Antibody
Supplier: List Biological Laboratories, Inc.
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ANTIGEN ANTHRAX PROACTIVE F/B ANTHRACIS
Supplier: List Biological Laboratories, Inc.
ANTIGEN ANTHRAX PROACTIVE F/B ANTHRACIS
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ANTHRAX PA RE QD VIAL
Supplier: List Biological Laboratories, Inc.
ANTHRAX PA RE QD VIAL
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PEPTIDE UNQUENCHED CALIBRATION 50NMOLE
Supplier: List Biological Laboratories, Inc.
PEPTIDE UNQUENCHED CALIBRATION 50NMOLE
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BOTULINUM TOXIN F LC RE VIAL
Supplier: List Biological Laboratories, Inc.
BOTULINUM TOXIN F LC RE VIAL
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ANTHRAX LETHAL FACTOR RE NATIVE VIAL
Supplier: List Biological Laboratories, Inc.
ANTHRAX LETHAL FACTOR RE NATIVE VIAL
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ANTI-BOTULINUM TOXIN B VIAL2
Supplier: List Biological Laboratories, Inc.
ANTI-BOTULINUM TOXIN B VIAL2
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SHIGA LIKE TOXIN 2 VIAL
Supplier: List Biological Laboratories, Inc.
SHIGA LIKE TOXIN 2 VIAL
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ANTI-SHIGA LIKE 2 MOUSE VIAL
Supplier: List Biological Laboratories, Inc.
ANTI-SHIGA LIKE 2 MOUSE VIAL
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CHOLERA TOXIN B SUBUNIT VIAL
Supplier: List Biological Laboratories, Inc.
CHOLERA TOXIN B SUBUNIT VIAL
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ANTI-SHIGA LIKE 1 MOUSE VIAL
Supplier: List Biological Laboratories, Inc.
ANTI-SHIGA LIKE 1 MOUSE VIAL
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CHOLERA TOX QD AZIDE-FREE VIAL
Supplier: List Biological Laboratories, Inc.
CHOLERA TOX QD AZIDE-FREE VIAL
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PERTUSSIS TOXIN IN GLYCEROL VIAL1
Supplier: List Biological Laboratories, Inc.
PERTUSSIS TOXIN IN GLYCEROL VIAL1
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TETANUS TOXIN LIGHT CHAIN RE
Supplier: List Biological Laboratories, Inc.
TETANUS TOXIN LIGHT CHAIN RE
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ANTI-BOTULINUM TOXIN A VIAL1
Supplier: List Biological Laboratories, Inc.
ANTI-BOTULINUM TOXIN A VIAL1
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ANTHRAX PA RE VIAL1
Supplier: List Biological Laboratories, Inc.
ANTHRAX PA RE VIAL1
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LIPOPOLYSACCHARIDE FROM E. COLI O55:B5
Supplier: List Biological Laboratories, Inc.
LIPOPOLYSACCHARIDE FROM E. COLI O55:B5