636 Results for: "Ingenol-5,20-acetonide"

Supplier: Anaspec Inc

Cathepsin B is a member of the cathepsin family consisting of 12 cysteine proteases with broad exo- and endopeptidase activity

Supplier: Anaspec Inc

The SensoLyte® 520 HCV Assay Kit uses a new FRET peptide substrate that incorporates 5-FAM (fluorophore) and QXL® 520 (quencher) for a continuous measurement of enzyme activities. In the intact FRET peptide, the fluorescence of 5-FAM is quenched by QXL® 520. Upon cleavage of the FRET peptide by HCV NS3/4a protease, the fluorescence of 5-FAM is recovered and can be continuously monitored at excitation/emission = 490 nm/520 nm. With superior fluorescence quantum yield and longer emission wavelength, this 5-FAM/QXL® 520-based FRET peptide shows less interference from autofluorescence of test compounds and cellular components. This assay is ten times more sensitive than an EDANS/DABCYL based assay and can detect 0.1 pmole of HCV NS3/4a protease. The assays are performed in a convenient 96-well or 384-well microplate format.

Supplier: Anaspec Inc

Neprilysin (NEP) is a transmembrane metallopeptidase normally expressed by a variety of tissues

Supplier: Anaspec Inc

Cathepsin L, a lysosomal endopeptidase, is a member of the papain-like family of cysteine proteinases

Supplier: Anaspec Inc

Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a sensitive substrate for assaying MMP-7, 12 and 13 activities, Abs/Em = 494/521 nm.
Sequence:QXL™ 520-PYAYWMRK(5-FAM)-NH2
MW:1963.1 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

This fluorogenic HIV-1 protease substrate contains the FRET pair HiLyte488 (fluorophore) and QXL520 (quencher), and a γ-Abu spacer. This FRET substrate is cleaved by the HIV-1 protease to generate fuorescence (Ex = 490nm; Em = 520nm).
Sequence:QXL™520-GABA-SQNYPIVQ-K(HiLyte Fluor™ 488)-NH2
MW:2008.1 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases

Supplier: Anaspec Inc

The calpains are a family of intracellular Ca²⁺ dependent cysteine proteases

Supplier: Anaspec Inc

Tobacco Etch Virus (TEV) proteinase is widely used to remove fusion tags from recombinant proteins

Supplier: AAT BIOQUEST INC

Cal-520® provides a robust homogeneous fluorescence-based assay tool for detecting intracellular calcium mobilization.

Supplier: Anaspec Inc

MMP-1 (interstitial collagenase, fibroblast collagenase) is an extracellular protease

Supplier: UNIVET OPTICAL TECHNOLOGIES

The 520 Basic over spectacle can be worn alone or over prescription glasses.

Supplier: Anaspec Inc

Deubiquitinating enzymes (DUBs) are proteases that reverse ubiquitin modifications and can rescue a protein from proteasomal degradation

Supplier: Anaspec Inc

Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components

Supplier: Anaspec Inc

Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components

Supplier: TCI America

CAS Number: 520-18-3
MDL Number: MFCD00016938
Molecular Formula: C15H10O6
Molecular Weight: 286.24
Purity/Analysis Method: >97.0% (HPLC)
Form: Crystal

Supplier: Anaspec Inc

Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This substrate is hydrolyzed rapidly by MMP-13, but slowly by MMP-1, 2, 3, 8, 9 and 12, Abs/Em = 494/521 nm.
Sequence:QXL™ 520-PLGLWArK(5-FAM)-NH2
MW:1789.9 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: AAT BIOQUEST INC

mFluor™ UV 520 dyes have fluorescence excitation and emission maxima of ~350 nm and ~520 nm respectively.

Supplier: Anaspec Inc

Renin, a highly specific aspartyl protease, cleaves angiotensinogen, to yield angiotensin I, which is further converted into angiotensin II by ACE (Angiotensin Converting Enzyme)

Supplier: Anaspec Inc

Aggrecanases belong to ADAMTS (A disintegrin and metalloprotease with thrombospondin motif) family of proteases

Supplier: Anaspec Inc

Thrombin, a serine protease, plays a central role in hemostasis by converting soluble plasma fibrinogen into an insoluble fibrin clot and by promoting platelet aggregation

Supplier: Anaspec Inc

Enterokinase is a heterodimeric serine protease produced by cells in the duodenal wall

Supplier: TCI America

CAS Number: 14347-78-5
MDL Number: MFCD00003213
Molecular Formula: C6H12O3
Molecular Weight: 132.16
Purity/Analysis Method: >97.0% (GC)
Form: Clear Liquid
Boiling point (°C): 78
Flash Point (°C): 80
Specific Gravity (20/20): 1.07
Specific rotation [a]20/D: -14 deg (neat)

Supplier: Anaspec Inc

Cathepsin D is the lysosomal aspartic proteinase, active in intracellular protein breakdown

Supplier: Anaspec Inc

Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a sensitive substrate for assaying MMP-1, 2, 7, 8, 12 and 13 activities, Abs/Em = 494/521 nm.
Sequence:5-FAM-PLGL-Dap(QXL™ 520)-AR-NH2
MW:1560.6 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a sensitive substrate for assaying MMP-1, 2, 7, 8, 12, 13 and 14 activities, Abs/Em = 494/521 nm.
Sequence:QXL™ 520 -γ-Abu-PQGL-Dab(5-FAM)-AK-NH2
MW:1647.7 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: TCI America

CAS Number: 520-36-5
MDL Number: MFCD00006831
Molecular Formula: C15H10O5
Molecular Weight: 270.24
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal

Supplier: Ambeed

5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4H-chromen-4-one, Purity: 95%, CAS Number: 520-32-1, Appearance: Solid, Storage: Sealed in dry, 2-8 C, Size: 1mg

Supplier: TCI America

CAS Number: 520-33-2
MDL Number: MFCD00075646
Molecular Formula: C16H14O6
Molecular Weight: 302.28
Purity/Analysis Method: >97.0% (HPLC,T)
Form: Crystal
Melting point (°C): 232
Specific rotation [a]20/D: -4 deg (C=1.8, EtOH)

Supplier: Biolegend

CD20 Monoclonal Antibody, Clone: SA275A11, Reactivity: Mouse, Isotype: Rat IgG2b, ?, Conjugate: KIRAVIA Blue 520 Monoclonal Antibody, , Immunogen: Mouse CD20 - transfected cells, Size: 100uG