2521 Results for: "Genscript"

Supplier: Genscript

The product is specific for infliximab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody GenScript, A02041-40, anti-infliximab antibody (23H5), mAb, mouse.

Supplier: Genscript

The product is specific for Bevacizumab. This antibody blocks Bevacizumab binding with VEGF165 (Z02689, VEGF165, Human). The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A01895-40, MonoRab Anti-Bevacizumab Antibody (30E1), mAb, Rabbit.

Supplier: Genscript

GenScript MonoRab™ Rabbit Anti-Camelid VHH Cocktail [HRP] is specific for Camelid sdAb (Llama and Camel). It has no cross-reactivity with mouse, rat, rabbit, goat or human immunoglobulins.

Supplier: Genscript

PSA monoclonal antibodies (5B10D4, 8A9B8, 1G9G8, 4A5D10 and 1A7D4) recognize total PSA, freePSA and ACT- PSA Complex (Prostate Specific Antigen/a-1 Antichymotrypsin Complex).

Supplier: Genscript

The product is specific for durvalumab.

Supplier: Genscript

The product is specific for Obinutuzumab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody GenScript, A01947-40, Anti-Obinutuzumab Antibody (16B7) [Biotin], mAb, Mouse.

Supplier: Genscript

The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A01966-40, MonoRab Anti-Obinutuzumab Antibody (8G12), mAb, Rabbit.

Supplier: Genscript

GenScript MonoRab™ Rabbit Anti-Camelid VHH Cocktail [Biotin] is specific for Camelid VHH antibody (Llama, Alpaca and Camel). It has no cross-reactivity with mouse, rat, rabbit, goat or human immunoglobulins.

Supplier: Genscript

GenScript rabbit anti-V5-tag polyclonal antibody specifically recognizes V5 tagged fusion proteins.

Supplier: Genscript

The product is specific for human TIGIT.

Supplier: Genscript

GenScript Human β-Amyloid 1-42 Antibody (2C2G5), mAb, Mouse detects human β-Amyloid 1-42 and does not cross-react with human β-Amyloid 1-40.

Supplier: Genscript

THE™ V5 Tag antibody [Biotin], mAb, Mouse recognizes N-terminal and C-terminal V5 tagged fusion proteins.

Supplier: Genscript

THE™ V5 Tag antibody [HRP], mAb, Mouse recognizes C-terminal tagged fusion proteins and it slightly recognizes N-terminal V5 tagged fusion proteins.

Supplier: Genscript

The product is specific for Pembrolizumab.

Supplier: Genscript

THE™ GST antibody [Biotin], mAb, Mouse recognizes C-terminal, N-terminal and internal tagged GST fusion proteins.

Supplier: Genscript

GenScript Purified Rabbit IgG (Whole Molecule) Control is highly purified from normal rabbit serum by Protein G chromatography.GenScript Purified Rabbit IgG (Whole Molecule) Control is suitable for use as control, standard, blocking agent, or coating protein in a variety of assays, including ELISA, immunobloting (Dot blot and Western blot), immunoprecipitation, immunodiffusion, and immunoelectrophoresis.It also may be used as antigen or ligand in immunochemical reactions and conjugations.

Supplier: Genscript

THE™ NWSHPQFEK Tag antibody, mAb, Mouse recognizes NWSHPQFEK tags localized at the N-terminal and C-terminal region of Strep II-tagged fusion proteins.

Supplier: Genscript

THE™ NWSHPQFEK Tag antibody [HRP], mAb, Mouse recognizes N-terminal and C-terminal Strep II tagged fusion proteins.

Supplier: Genscript

SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease 2019 (COVID-19). Nucleocapsid Protein is a most abundant structure protein of the coronavirus which is associated with nucleic acid. SARS-CoV-2 Nucleocapsid Antibody (N22IgA), Human Chimeric is produced from cell culture in vitro under conditions free from animal-derived components.

Supplier: Genscript

Dupilumab with trade name Dupixent, is an FDA-approved drug for the treatment of patients aged 6 years and older with moderate-to-severe atopic dermatitis. It is a human monoclonal antibody. Dupilumab binds to the interleukin-4 receptor alpha (IL-4R alpha) subunit shared by the interleukin (IL)-4 and IL-13 receptor complexes, thereby inhibiting IL-4 and IL-13 signaling. Anti-Dupilumab Antibody (2D5), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Dupilumab.

Supplier: Genscript

Immunoglobulin M (IgM) is one of several isotypes of antibodies (also known as immunoglobulin) that are produced by vertebrates. IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. Formed from covalently linking 5 immunoglobulins together. Anti-human IgM mu chain antibody is ideal for investigators in Immunology, Microbiology, and Cell Biology.

Supplier: Genscript

A camelid single-domain antibody (sdAb, called Nanobody by Ablynx, the developer) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody, these are called VHH fragments. Like a whole antibody, it is able to bind selectively to a specific antigen. Single-domain antibodies allow a broad range of applications in biotechnical as well as therapeutic uses due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.

Supplier: Genscript

Denosumab with trade name Prolia, is an FDA-approved drug for the treatment of patients with osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. Denosumab is a fully human monoclonal antibody that works as a RANK ligand (RANKL) inhibitor. Denosumab can bind RANKL, preventing RANKL from activating RANK, its receptor on the osteoclast surface. Anti-Denosumab Antibody (9A10), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Denosumab.

Supplier: Genscript

Avelumab with trade name Bavencio, is an FDA-approved drug to treat Merkel cell carcinoma, urothelial carcinoma, and renal cell carcinoma. Avelumab is a whole monoclonal antibody of isotype IgG1 that binds to the programmed death-ligand 1 (PD-L1) and therefore inhibits binding to its receptor programmed cell death 1 (PD-1). PD-L1 can be highly expressed on certain tumors, which is thought to lead to reduced activation of immune cells (cytotoxic T-cells in particular) that might otherwise recognize and attack the cancer. Inhibition of PD-L1 by Avelumab can remove this inhibitor effect and thereby engender an anti-tumor response. It is one of several ways to block inhibitory signals related to T-cell activation, a more general strategy known as 'immune checkpoint inhibition'.Anti-Avelumab Antibody (12G9), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Avelumab.

Supplier: Genscript

Golimumab with trade name Simponi, is an FDA-approved drug for the treatment of Rheumatoid arthritis (RA), Psoriatic Arthritis (PsA), Ankylosing Spondylitis (AS) and Ulcerative Colitis (UC). It is a human IgG1κ monoclonal antibody that binds to Tumor Necrosis Factor alpha (TNF-alpha), thereby inhibiting the binding to TNF alpha receptors and subsequent generation of inflammatory cytokines. GenScript Anti-Golimumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Golimumab.

Supplier: Genscript

Adeno-associated virus (AAV) is a single-stranded DNA virus that commonly infects humans without pathology. Therefore, AAV can be engineered to deliver DNA to target cells as a vector for gene therapy. There are several serotypes including AAV type 1, 2, 5, 6, 8, 9, DJ and rh.1. Among them, AAV2 is the best characterized and most commonly used. Cap gene of AAV gives rise to three capsid proteins, VP1, VP2 and VP3, with molecular weight of 87, 72 and 62 kDa, respectively. These capsid proteins assemble into a near-spherical protein shell of 60 subunits for AAV.

Supplier: Genscript

Human IgG is the major immunoglobulin in blood and plays a key role in the humoral immune response. The Fc portion of human IgG binds to Fc receptor that can activate the complement system. Fc-tagged proteins are generated with DNA recombinant technology. The protein of interest is fused with the Fc tag. Most vectors encoding for Fc tag sequence use the Fc region of human IgG1. Protein A can be used for the purification of Fc-tagged proteins. Human IgG (Fc), mAb, Mouse is a useful tool for immunoassay of human Fc-tagged proteins and human IgG.GenScript Human IgG (Fc) Antibody, mAb, Mouse is produced from the hybridoma resulting from fusion of SP2/0-Ag14 myeloma and B-lymphocytes obtained from mouse immunized with human Fc-tagged protein.

Supplier: Genscript

Pertuzumab (also called 2C4, trade name Perjeta) is a monoclonal antibody used in combination with trastuzumab and docetaxel for the treatment of metastatic HER2-positive breast cancer; it is also used in the same combination as a neoadjuvant in early HER2-positive breast cancer. The epitope for pertuzumab is the domain of HER2 where it binds to HER3, and pertuzumab prevents the HER2/HER3 dimer from forming, which in turn blocks signaling by the dimer and as a result prevents HER2 from functioning. Anti-Pertuzumab Antibody (1A3), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Pertuzumab.

Supplier: Genscript

GenScript Rabbit Anti-GFP Polyclonal antibody reacts with GFP fusion proteins. The antibody also reacts with other variants of GFP, such as CFP, YFP, eGFP and GFPuv.

Supplier: Genscript

Genscript ToxinSensorTM Chromogenic LAL Endotoxin Assay Kit is designed to be a quantitative In Vitro end-point endotoxin test for human and animal parenteral drugs, biological products, and medical devices.