"Genscript"

Supplier: Genscript

Ustekinumab with trade name Stelara, is an FDA-approved drug to Crohn's disease, Ulcerative Colitis, Plaque Psoriasis and Psoriatic Arthritis, targeting both interleukins (IL)-12 and IL-23. Ustekinumab is a fully human immunoglobulin G1 kappa mAb that binds to IL-12 and IL-23. Ustekinumab binds to the p40 subunit common to IL-12 and IL-23 and prevents their interaction with the IL-12 receptor β1 subunit of the IL-12 and IL-23 receptor complexes, thereby disrupting the proinflammatory pathway. Anti-Ustekinumab Antibody (11E3), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Ustekinumab.

Supplier: Genscript

Recombinant Enterokinase protein

Supplier: Genscript

Rabbit IgG control is suitable for use as control, standard, blocking agent, or coating protein in a variety of assays, including ELISA, western blot, immunoprecipitation, immunodiffusion, and immunoelectrophoresis, flow cytometry and immunofluorescence. GenScript MonoRab™ rabbit IgG control [iFluor 647] (whole molecule), mAb is iFluor 647 conjugated MonoRab™ rabbit IgG control (whole molecule), mAb.

Supplier: Genscript

The product is specific for bevacizumab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A01975-40, anti-bevacizumab antibody (4H1), mAb, mouse.

Supplier: Genscript

The specificity of the antibody is defined as the ratio of antigen concentration to cross-reactant concentration at 50% inhibition of maximum binding.

Supplier: Genscript

GenScript MonoRab™ anti-His tag (C-term) antibody (25B6E11), mAb, rabbit specifically recognizes His tags placed at C-terminal and internal regions of His-fusion
proteins. This product is not recommended for N-terminal His-fusion protein detection and nbsp.

Supplier: Genscript

GenScript THE™ DYKDDDDK Tag antibody [FITC], mAb, Mouse recognizes C-terminal, N-terminal and internal DYKDDDDK tagged fusion proteins.

Supplier: Genscript

HSA Antibody (2C7B4), mAb, Mouse recognizes HSA proteins and it has no cross-reactivity with mouse serum albumin, rabbit serum albumin, BSA and OVA.

Supplier: Genscript

GenScript MonoRab™ Beta-Actin Antibody, mAb, Rabbit reacts with mouse, human, hamster, and rat. It has not yet been tested in other species.

Supplier: Genscript

Human IgG is the major immunoglobulin in blood and plays a key role in the humoral immune response. The Fc portion of human IgG binds to Fc receptor that can activate the complement system. Fc-tagged proteins are generated with DNA recombinant technology. The protein of interest is fused with the Fc tag. Most vectors encoding for Fc tag sequence use the Fc region of human IgG1. Protein A can be used for the purification of Fc-tagged proteins. Human IgG (Fc), mAb, Mouse is a useful tool for immunoassay of human Fc-tagged proteins and human IgG.GenScript Human IgG (Fc) Antibody, mAb, Mouse is produced from the hybridoma resulting from fusion of SP2/0-Ag14 myeloma and B-lymphocytes obtained from mouse immunized with human Fc-tagged protein.

Supplier: Genscript

MonoRab™ HA tag antibody recognizes HA tags placed at N-terminal, C-terminal, and internal regions of fusion proteins.

Supplier: Genscript

Dupilumab with trade name Dupixent, is an FDA-approved drug for the treatment of patients aged 6 years and older with moderate-to-severe atopic dermatitis. It is a human monoclonal antibody. Dupilumab binds to the interleukin-4 receptor alpha (IL-4R alpha) subunit shared by the interleukin (IL)-4 and IL-13 receptor complexes, thereby inhibiting IL-4 and IL-13 signaling. Anti-Dupilumab Antibody (2D5), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Dupilumab.

Supplier: Genscript

The product is specific for Rituximab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody GenScript, A01970-40, Anti-Rituximab Antibody (17B6), mAb, Mouse.

Supplier: Genscript

A camelid single-domain antibody (sdAb, called Nanobody by Ablynx, the developer) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody, these are called VHH fragments. Like a whole antibody, it is able to bind selectively to a specific antigen. Single-domain antibodies allow a broad range of applications in biotechnical as well as therapeutic uses due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.

Supplier: Genscript

Denosumab with trade name Prolia, is an FDA-approved drug for the treatment of patients with osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. Denosumab is a fully human monoclonal antibody that works as a RANK ligand (RANKL) inhibitor. Denosumab can bind RANKL, preventing RANKL from activating RANK, its receptor on the osteoclast surface. Anti-Denosumab Antibody (9A10), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Denosumab.

Supplier: Genscript

THE™ NWSHPQFEK Tag antibody [HRP], mAb, Mouse recognizes N-terminal and C-terminal Strep II tagged fusion proteins.