"Genetex"

Supplier: Genetex

Rat Monoclonal antibody [V1q] to TNF alpha

Supplier: Genetex

Mouse monoclonal antibody [2B10] to HIF1 beta

Supplier: Genetex

Rabbit polyclonal antibody to CKS-2 (CDC28 protein kinase regulatory subunit 2)

Supplier: Genetex

Purity: IgG fraction Species Reactivity: Human Tested Applications: IP, WB Pkg Size: 100 ul

Supplier: Genetex

POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, that occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression (Schreiber et al., 1993 [PubMed 8441633]; Atanasoski et al., 1995 [PubMed 7601453]).[supplied by OMIM]

Supplier: Genetex

Rabbit polyclonal to MEK1 ( phospho T292 )

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Clone: B62-FE2 Conjugation: Biotin Purity: Protein A purified Species Reactivity: Virus Tested Applications: ELISA, WB Pkg Size: 125 ul

Supplier: Genetex

Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).[supplied by OMIM]

Supplier: Genetex

Rabbit polyclonal antibody to KLB (Middle)

Supplier: Genetex

Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.

Supplier: Genetex

CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

Supplier: Genetex

Rabbit Polyclonal antibody to ASZ1 (ankyrin repeat, SAM and basic leucine zipper domain containing 1)

Supplier: Genetex

Rabbit Polyclonal antibody to Splicing Factor 1

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Mouse monoclonal antibody [311] to Apolipoprotein A1

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Rabbit Polyclonal antibody to RPL11 (ribosomal protein L11)

Supplier: Genetex

Mouse monoclonal antibody [VFF-17] to CD44v7/8