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145794 Results for: "Gallic+acid+monohydrate"

Anti-TRDMT1 Rabbit Polyclonal Antibody (Cy5®)

Supplier: Bioss

Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, and this methylation results in transcriptional repression of the target gene. The Dnmt enzymes are encoded by independent genes. Dnmt1 is the most abundant, and it preferentially methylates hemimethylated DNA and coordinates gene expression during development. Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3. Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, is expressed at substantially lower levels in adult tissues, and is likely involved in methylating newly integrated retroviral DNA. Dnmt3a and Dnmt3b are encoded by two distinct genes, but both are abundantly expressed in embryonic stem cells, where they also methylate CpG motifs on DNA.

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Anti-TRDMT1 Rabbit Polyclonal Antibody

Supplier: Bioss

Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, and this methylation results in transcriptional repression of the target gene. The Dnmt enzymes are encoded by independent genes. Dnmt1 is the most abundant, and it preferentially methylates hemimethylated DNA and coordinates gene expression during development. Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3. Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, is expressed at substantially lower levels in adult tissues, and is likely involved in methylating newly integrated retroviral DNA. Dnmt3a and Dnmt3b are encoded by two distinct genes, but both are abundantly expressed in embryonic stem cells, where they also methylate CpG motifs on DNA.

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DRG® Troponin I ELISA, DRG International

DRG® Troponin I ELISA, DRG International

Supplier: DRG International

An enzyme immunoassay for the quantitative determination of caridac specific troponin I in serum.

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PharMed® BPT Biocompatible Tubing, Saint-Gobain Life Sciences

PharMed® BPT Biocompatible Tubing, Saint-Gobain Life Sciences

Supplier: Saint Gobain Life Sciences

PharMed® BPT is designed to maintain fluid integrity during fluid transport. Transporting biocompatible fluids through a peristaltic pump limits the risk of fluid contact with any portion of the pump itself. PharMed® BPT tubing has been formulated to withstand the rigors of peristaltic pumping action while providing the biocompatible fluid surface required in sensitive applications.

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Corning® Lambda™ EliteMax Benchtop Workstation, Corning

Corning® Lambda™ EliteMax Benchtop Workstation, Corning

Supplier: Corning

The New Corning® LAMBDA™ EliteMax Semi-Automated Benchtop Pipettor is the optimal solution for purification, isolation, and extraction for sample prep and compound management workflows.

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Elizabethkingia meningoseptica Recombinant N-Glycanase (PNGase F) (from E. coli)

Elizabethkingia meningoseptica Recombinant N-Glycanase (PNGase F) (from E. coli)

Supplier: AGILENT TECHNOLOGIES, INC (CSD)

AdvanceBio N-Glycanase (PNGase F), ≥2.5 U/mL (formerly ProZyme). A recombinant form of PNGase F, releases intact N-glycans by cleaving between the innermost GlcNAc and Asn. Includes 5x N-glycanase reaction buffer, denaturation solution, detergent solution, 5x N-glycanase Tris reaction buffer (MS applications). Supplied at a concentration of ≥ 2.5 U/mL. For a more concentrated formulation of ≥ 10 U/mL, which may be useful for native digestions, see GKE-5010B or GKE-5020B (EDTA-free).

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ADP-Glo Kinase Assay + MYO3 beta Kinase Enzyme System, 1 each, Promega

ADP-Glo Kinase Assay + MYO3 beta Kinase Enzyme System, 1 each, Promega

Supplier: Promega Corporation

Recombinant human MYO3 beta (1-326) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. MYO3 beta is a member of the Class III myosins that are actin-dependent motor proteins containing an amino-terminal kinase domain.

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ADP-Glo Kinase Assay + p70S6Kb Kinase Enzyme System, 1 each, Promega

ADP-Glo Kinase Assay + p70S6Kb Kinase Enzyme System, 1 each, Promega

Supplier: Promega Corporation

Recombinant full-length human p70S6Kb was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. p70S6Kb is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases and is activated by mitogenic stimuli.

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P450-Glo CYP2D6 Assay, Promega

P450-Glo CYP2D6 Assay, Promega

Supplier: Promega Corporation

The P450-Glo Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays

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ADP-Glo Kinase Assay + PKC theta Kinase Enzyme System, 1 each, Promega

ADP-Glo Kinase Assay + PKC theta Kinase Enzyme System, 1 each, Promega

Supplier: Promega Corporation

Recombinant full-length human PKC theta was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Protein Kinase C theta (PKC theta) is an important component in the intracellular signaling cascade.

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ADP-Glo Kinase Assay + IKK alpha Kinase Enzyme System, 1 each, Promega

ADP-Glo Kinase Assay + IKK alpha Kinase Enzyme System, 1 each, Promega

Supplier: Promega Corporation

Full-length recombinant human IKK alpha was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. IKK alpha is a serine/threonine protein kinase that phosphorylates the I-kappa-B protein.

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ADP-Glo Kinase Assay + NIK Kinase Enzyme System, 1 each, Promega

ADP-Glo Kinase Assay + NIK Kinase Enzyme System, 1 each, Promega

Supplier: Promega Corporation

Recombinant human NIK (325-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. NIK is a mitogen-activated protein kinase kinase kinase 14 (MAP3K14), which binds to TRAF2 and stimulates NF-kappaB activity.

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ADP-Glo Kinase Assay + MLK2 Kinase Enzyme System, 1 each, Promega

ADP-Glo Kinase Assay + MLK2 Kinase Enzyme System, 1 each, Promega

Supplier: Promega Corporation

Recombinant human MLK2 (1-446) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. MLK2 or mixed-lineage kinase 2 is a member of the serine/threonine kinase family, which activates MAPK8/JNK1 and MKK4/SEK1.

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ADP-Glo Kinase Assay + PASK Kinase Enzyme System, 1 each, Promega

ADP-Glo Kinase Assay + PASK Kinase Enzyme System, 1 each, Promega

Supplier: Promega Corporation

Recombinant human PASK (981-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PASK or PAS domain containing serine/threonine kinase regulates the function of many intracellular signaling pathways involved in stress.

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GenePix 4300 and 4400 Microarray Scanner, Molecular Devices

GenePix 4300 and 4400 Microarray Scanner, Molecular Devices

Supplier: Molecular Devices

The GenePix® 4300A and GenePix® 4400A Scanners from Molecular Devices offer maximum imaging quality with optimal resolution in highly configurable platforms.

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Concanavalin A (from Jackbean), MP Biomedicals

Supplier: MP Biomedicals

Pure Canavalia ensiformis lectin (Con A) from Jackbean.

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P450-Glo CYP2B6 Assay, Promega

P450-Glo CYP2B6 Assay, Promega

Supplier: Promega Corporation

The P450-Glo Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays

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Heparin Sepharose™ 6 Fast Flow Affinity Chromatography Media, Cytiva

Heparin Sepharose™ 6 Fast Flow Affinity Chromatography Media, Cytiva

Supplier: Cytiva

Heparin Sepharose 6 Fast Flow is composed of cross-linked 6% agarose beads modified sodium heparin. Immobilization is performed using chemically stable and oriented coupling giving high binding capacity. The chemical stability of the media is solely dictated by the heparin ligand. Heparin Sepharose 6 Fast Flow is a member of the Cytiva range of affinity chromatography media for capture and intermediate purification.

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Anti-TRDMT1 Rabbit Polyclonal Antibody

Anti-TRDMT1 Rabbit Polyclonal Antibody

Supplier: Prosci

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. TRDMT1 is a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome.CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Globe Glass™ Graduated Cylinders, To Deliver, Globe Scientific

Globe Glass™ Graduated Cylinders, To Deliver, Globe Scientific

Supplier: Globe Scientific

Globe Glass™ graduated cylinders are calibrated to ASTM E1272 standards for precise measurement of volumes of liquids. A solid hexagonal base provides stability, and an included polyethylene (PE) bumper guard helps to protect against accidental breakage. These graduated cylinders are calibrated TD, 'To Deliver', and are available in sizes ranging from 5 to 2000 ml, with Class A or Class B calibration tolerance options. Class A graduated cylinders include a batch calibration certificate.

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Anti-TRDMT1 Rabbit Polyclonal Antibody (Cy7®)

Supplier: Bioss

Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, and this methylation results in transcriptional repression of the target gene. The Dnmt enzymes are encoded by independent genes. Dnmt1 is the most abundant, and it preferentially methylates hemimethylated DNA and coordinates gene expression during development. Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3. Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, is expressed at substantially lower levels in adult tissues, and is likely involved in methylating newly integrated retroviral DNA. Dnmt3a and Dnmt3b are encoded by two distinct genes, but both are abundantly expressed in embryonic stem cells, where they also methylate CpG motifs on DNA.

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Anti-AMPK alpha 1 (Ser356) Rabbit Polyclonal Antibody

Supplier: Bioss

Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators.

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Semivolatile Calibration Kit #3 (with Benzidine), Restek

Semivolatile Calibration Kit #3 (with Benzidine), Restek

Supplier: Restek

Contains 1 ml each of the following mixtures, SV calibration mix #1 (anilines), SV calibration mix #2 (phenols), SV calibration mix #3 (base neutrals), SV calibration mix #4 (base neutrals), SV calibration mix #5 (PAHs), SV calibration mix #7 (dichlorobenzenes) and 605 benzidines calibration mix (benzidine and 3,3'-dichlorobenzidine).

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Globe Glass™ Volumetric Flasks, To Contain, Globe Scientific

Globe Glass™ Volumetric Flasks, To Contain, Globe Scientific

Supplier: Globe Scientific

Globe Glass™ volumetric flasks are calibrated to meet ASTM tolerance specifications for precise measurement in solution preparation and dilution. A diamond etched graduation line indicates the calibrated capacity of each measuring flask. Wide mouth options are available for easier filling and mixing. Globe Glass™ volumetric flasks are offered in sizes ranging from 1 to 2000 ml, and with Class A or Class B calibration tolerances. Class A volumetric flasks include a batch calibration certificate.

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Mouse/Rat Urocortin 1 ELISA Assay Kit, Eagle Biosciences

Supplier: Eagle Biosciences

Mouse Rat Urocortin 1 ELISA determines the concentration of urocortin 1 in mouse & rat plasma,serum.

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P450-Glo™ CYP2D6 Screening System, 1000 Assays, Promega

P450-Glo™ CYP2D6 Screening System, 1000 Assays, Promega

Supplier: Promega Corporation

The P450-Glo Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays

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Corning® Transwell® Inserts, Sterile, Corning

Corning® Transwell® Inserts, Sterile, Corning

Supplier: Corning

Transwell® cell culture inserts are convenient, easy to use permeable support devices for the study of both anchorage-dependent and anchorage-independent cell lines. They are designed to produce a cell culture environment that closely resembles the in vivo state.

    
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Tetrasodium diphosphate decahydrate ≥99%, crystals ACS

Supplier: Spectrum Chemicals

Sodium Pyrophosphate, Decahydrate, Crystal, Reagent, ACS is also known as tetrasodium pyrophosphate and is employed as a buffering agent as well as a thickening agent and can be found in many foods under the shape of a food additive. It is also used in toothpaste to aid in tartar control in the mouth. As an ACS grade quality reagent, its chemical specifications are the de facto standards for chemicals used in many high-purity applications and typically designate the highest quality chemical available for laboratory use. Spectrum Chemical manufactured Reagent ACS grade products meet the toughest regulatory standards for quality and purity.

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P450-Glo CYP1A2 Induction/Inhibition Assay, Promega

P450-Glo CYP1A2 Induction/Inhibition Assay, Promega

Supplier: Promega Corporation

The P450-Glo CYP1A2 Assay and Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays

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Anti-FAS Rabbit Polyclonal Antibody

Anti-FAS Rabbit Polyclonal Antibody

Supplier: Genetex

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. At least eight alternatively spliced transcript variants encoding seven distinct isoforms have been described. The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq]

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