Supplier: Boster Biological Technology

Rabbit IgG polyclonal antibody for Transcription factor A, mitochondrial(TFAM) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Supplier: MilliporeSigma

Expansion of a GGGGCC hexanucleotide repeat sequence in the non-coding region of human chromosome 9 open reading frame 72 or C9orf72 (also known as ALSFTD, FTDALS; Gene ID 203228) is the most common genetic abnormality in familial and sporadic frontotemporal dementia (FTD) and motor neuron disease (MND), with amyotrophic lateral sclerosis (ALS) as the most frequent form. The number of hexanucleotide repeats in the normal population ranges from 2 to 24, whereas up to several thousand repeats (700 to 4,400 repeats) are found in the pathologically expanded allele.

Supplier: Promega Corporation

Recombinant human PASK (981-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PASK or PAS domain containing serine/threonine kinase regulates the function of many intracellular signaling pathways involved in stress.

Supplier: Promega Corporation

Recombinant human DAPK1 (1-363) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Death-associated protein kinase 1 (DAPK1) is a positive mediator of apoptosis induced by gamma-interferon.

Supplier: Promega Corporation

Full-length recombinant human CAMK1 gamma was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CAMK1 gamma (CLICK-III), a member of the CAMK family, is a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase.

Supplier: Promega Corporation

Recombinant human FMS (539-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. FMS is a proto-oncogene that encodes the tyrosine kinase transmembrane receptor for colony stimulating factor 1 receptor (CSF1R).

Supplier: Promega Corporation

Recombinant full-length human CHK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CHK2 is rapidly phosphorylated and activated in response to replication blocks and DNA damage.

Supplier: Promega Corporation

Recombinant full-length human PIM1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PIM1 is a proto-oncogene that belongs to a family of serine/threonine protein kinases that are highly conserved in multicellular organisms.

Supplier: Promega Corporation

Recombinant human c-KIT (544-end) was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. c-KIT is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor).

Supplier: Promega Corporation

Recombinant human ULK1 (1-649) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. ULK1 is a serine/threonine protein kinase that plays a critical role during initial stages of autophagy, a vital response to nutrient starvation.

Supplier: Lovibond

The XD series instruments are ideal for routine and spectral analysis. As true all-rounders, the XD 7000 and XD 7500 facilitate work routines, especially with automatic method recognition using barcodes, automatic cell recognition and more than 150 pre-programmed methods. In addition to analytical quality control, they also support Good Labor Practice (GLP). The instruments are available together with bar-coded test tubes and a wide range of accessories from a single source - which is also easy on your wallet. High-quality reference beam optics, usability, easy handling, and multilingual global applicability round off the versatility of the VIS and UV/VIS spectrophotometers, which are also equipped for flexible on-site use.

Supplier: Eppendorf

Shake more. Shake faster. The temperature-controlled (refrigerated or non-refrigerated) Eppendorf Innova S44i shaker can fit up to twice as many flasks as other shakers and is ready to reliably support high-yield expression protocols at high speeds. The Eppendorf X-Drive maintains smooth shaking for more reproducible results.

Supplier: Biosensis

The Biosensis Neurotrophin 4/5 RapidTM enzyme-linked immunosorbent assay (ELISA) Kit is a sandwich ELISA that allows the specific, fast and reliable quantification of NT4/5 in less than 4 hours in cell culture supernatants, human citrate-plasma and brain extracts only if used as directed. Please refer to the kit protocol for specific use instructions for each substrate application, in particular blood samples.

Supplier: MP Biomedicals

RPMI 1640 Medium was originally developed to culture human leukemic cells in suspension and as a monolayer. Since, it has been found suitable for a variety of mammalian cells, including HeLa, Jurkat, MCF-7, PC12, PBMC, astrocytes, and carcinomas. RPMI has successfully been used for the cultivation of normal human and neoplastic leukocytes.

Supplier: Fujifilm Irvine Scientific

Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a member of the epidermal growth factor (EGF) family and is expressed by monocytes and macrophages. HB-EGF is the predominant growth factor involved in epithelialization during wound healing. HB-EGF signals through the receptor tyrosine kinase ErbB2 to maintain adult heart homeostasis, and promotes cardiac valve development through binding in high affinity to the epidermal growth factor receptor (EGFR). HB-EGF binds the the ErbB4 receptor tyrosine kinase to mediate implantation of the human blastocyst. HB-EGF also functions as a potent mitogen for fibroblasts and smooth muscle cells.

Supplier: Promega Corporation

Recombinant human FGFR3 (K650E) (397-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Fibroblast growth factor receptor 3 is part of a family of fibroblast growth factor receptors that share similar structure and function

Supplier: Promega Corporation

Recombinant full-length human MSK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Supplier: Promega Corporation

Recombinant human MINK1 (1-320) was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. MINK1 is a member of the germinal center family of kinases that are homologous to the Ste20 family and regulate a wide variety of cellular processes.

Supplier: Boster Biological Technology

Rabbit IgG polyclonal antibody for Heat shock cognate 71 kDa protein(HSPA8) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Supplier: Promega Corporation

LRRK2 or leucine-rich repeat kinase is a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain and a WD40 domain.

Supplier: Thermo Scientific Chemicals

Powder

Supplier: Promega Corporation

FLT3 is a receptor tyrosine kinase that has been shown to play a role in proliferation and survival of hematopoietic progenitor cells as well as differentiation of early B lymphoid progenitors.

Supplier: Promega Corporation

Recombinant human PDGFR alpha (D842V) (550-end) point mutant was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PDGFR alpha is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity.

Supplier: Invitrogen

Thermo Scientific Pierce SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

Supplier: Biosensis

The Biosensis proBDNF RapidTM ELISA Kit is a sandwich ELISA that allows the specific, fast and reliable quantification of proBDNF in less than 4 hours in cell culture supernatants, cell lysates, serum, citrate-plasma and tissue extracts only if used as directed. Please refer to the kit protocol for specific use instructions for each substrate application, in particular human blood samples.

Supplier: Promega Corporation

Recombinant human EIF2AK2 (252-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. EIF2AK2 (also known as double-stranded RNA-activated protein kinase) is shown to be involved in HIV/gp120-associated neurodegeneration.

Supplier: Promega Corporation

Recombinant full-length human MAPKAPK5 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. MAPKAPK5 is a member of the serine/threonine kinase family that responds to cellular stress and proinflammatory cytokines.

Supplier: Boster Biological Technology

Rabbit IgG polyclonal antibody for C-terminal-binding protein 1(CTBP1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Supplier: Cube Biotech

DIBMA stands for diisobutylene maleic acid copolymer, and is an extensively researched polymer. The fundamental properties of DIBMA include the absence of light absorption at a wavelength >250 nm, a crucial factor for protein detection via absorbance, and a high resistance to divalent cations.

Supplier: Promega Corporation

ALK2 is a receptor serine/threonine kinase that is member of the ALK family and is upstream of signaling pathway involving the SMAD proteins especially SMAD1/5/8.