4554 Results for: "Digital Thermometers&amp"

Supplier: Cayman Chemical Company

Cyclic GMP-AMP (cGAMP) synthase (cGAS; Item No. 22810) is a nucleotidyltransferase located in the cytosol that acts as a cytosolic DNA sensor to detect foreign DNA from microbial pathogens as part of the innate immune response. Upon binding to cytosolic DNA, cGAS produces the cyclic dinucleotide second messenger cGAMP, which activates stimulator of interferon genes (STING), leading to activation of the type I interferon (IFN) pathway. In vitro, fibroblasts, macrophages, and dendritic cells isolated from cGAS knockout (cGAS^-/-) mice do not produce type I IFNs following DNA transfection or DNA virus infection.{39163} Similarly, cells containing a frame-shift mutation in the cGAS locus fail to mount an immune response to HIV and other retroviruses.{39164} In vivo, cGAS^-/- mice infected with herpes simplex virus 1 (HSV-1) have lower levels of IFN-α and IFN-β, shorter survival times, and higher post-mortem levels of HSV-1 in the brain. Cayman’s cGAS Monoclonal Antibody (Clone 5G10) recognizes the full length human cGAS protein at ~59 kDa.

Supplier: WORLD PRECISION INSTRUMENTS LLC

The manual microsyringe pump is a convenient tool for precise manual injection of fluid using glass pipettes or similar injection devices. The design allows visual feedback of flow at the pipette tip. They can also be used as a manual micro syringe pump for perfusion or withdrawal of liquids. The resolution of the injection volume can be continuously varied from 10 nanoliters to the microliter range, depending on the syringe used.

Supplier: Atago

Economic pocket refractometer offers a wide Brix range

Supplier: Cayman Chemical Company

Cyclic GMP-AMP (cGAMP) synthase (cGAS) (161-522) is a truncated form of cGAS (Item No. 22810) that contains the nucleotidyltransferase and Mab21 domains. cGAS is a nucleotidyltransferase located in the cytosol that acts as a cytosolic DNA sensor to detect foreign DNA from microbial pathogens as part of the innate immune response. Upon binding to cytosolic DNA, cGAS produces the cyclic dinucleotide second messenger cGAMP, which activates stimulator of interferon genes (STING), leading to activation of the type I interferon (IFN) pathway. In vitro, fibroblasts, macrophages, and dendritic cells isolated from cGAS knockout (cGAS^-/-) mice do not produce type I IFNs following DNA transfection or DNA virus infection. Similarly, cells containing a frame-shift mutation in the cGAS locus fail to mount an immune response to HIV and other retroviruses. In vivo, cGAS^-/- mice infected with herpes simplex virus 1 (HSV-1) have lower levels of IFN-α and IFN-β, shorter survival times, and higher post-mortem levels of HSV-1 in the brain.

Supplier: Thermo Fisher Scientific

The Thermo Scientific Cimarec+™ series digital hotplates are designed to provide exceptional safety, and temperature performance for routine protocols

Supplier: Bioss

Amphiphysin is associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff man syndrome who were also affected by breast cancer are positive for auto against this protein. Alternate splicing of this gene results in two transcript variants (Amphiphysin 1 and Amphiphysin 2) encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined.

Supplier: Genetex

May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.

Supplier: Mortech Manufacturing

Constructed of a stainless steel base with an ABS indicator. Results quickly display on large backlit LCD screen. Four key membrane keypad with raised tactile keys.

Supplier: IKA Works

Roller shakers basic/digital with 6/10 rolls provides smooth rocking and rolling action at a fixed or infinately adjustable speed. Used for mixing blood samples, solid and liquid suspensions and viscous samples. The unit can be used with all conventional tubes and cylindrical bottles. Easily removable attachments allow quick cleaning in case of sample spills.

Supplier: Globe Scientific

The GHS-550 hotplate offers safety and precision for laboratory heating applications. The compact and low-profile design saves valuable benchtop space and a 7" chemical resistant glass ceramic working surface ensure years of service and easy cleanup.

Supplier: Analytik Jena US

ColonyDoc-It™ Imaging Station enables users to process automated, fast and accurate colony counting. The high resolution digital color camera is specifically designed to capture white light and fluorescent marked colonies. Capture colony sizes as small as 0.08mm. The station can accommodate pour, spread and spiral plates and filters with sizes from 33 to 150mm. The system offers researchers detection of bacteria, yeast and mold colonies and decreases time to count. Applications include fluids contamination, microbiology studies, antibiotic testing and hygiene studies.

Supplier: Heidolph NA, LLC

Designed as precise setting of rotation speed and heating bath temperature on the digital touch display or for quick access during an active process, directly via the knobs on the operating panel.

Supplier: Corning

The Corning® LSE High Speed Microcentrifuge features an easy-to-use, digital control interface and high-speed performance for quick nucleic acid and protein separations

Supplier: Antyila Scientific

Replace mercury manometers to elevate precision in vacuum measurements with portable or continuous-display absolute reference gauges.

Supplier: CRYSTAL TECHNOLOGY & INDUSTRIES

Cover, Vapor, For Wb-01A/Wb-02A, to insulate waterbath

Supplier: Chemglass

Bushing style adapters feature a lower standard taper inner joint and outer joint ground in the bore of the adapter.

Supplier: Chemglass

Adapter is vacuum jacketed and can be used as a distilling head to connect a condenser with the top of the distillation column.

Supplier: IKA Works

Supplier: Novus Biologicals

The AK2 Antibody (AT7E7) [Biotin] from Novus Biologicals is a mouse monoclonal antibody to AK2. This antibody reacts with human. The AK2 Antibody (AT7E7) [Biotin] has been validated for the following applications: Western Blot, ELISA, Immunocytochemistry / Immunofluorescence.

Supplier: YSI

These kits include a ProSolo dissolved oxygen meter, an ODO/CT probe assembly with cable, and a soft-sided carrying case. Automatically compensates DO for salinity.

Supplier: Antyila Scientific

Simple-to-use, general-purpose water bath for your laboratory.

Supplier: DWK Life Sciences (KIMBLE)

Provide dual entry into a variety of flasks.

Supplier: Bioss

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which may have distinct functions. [provided by RefSeq].

Supplier: Bioss

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which may have distinct functions. [provided by RefSeq].

Supplier: Chemglass

Adapters have a tubulation at the top for use with rubber fitting.

Supplier: Scientific Industries

Vortex Genie® Mixers are available in multiple models and with a vast array of available platforms and accessories.

Supplier: Eppendorf

Eppendorf MiniSpin® and MiniSpin® plus centrifuges are powerful, entry-level, easy-to-use centrifuges that are small enough to allow individual workstations to be equipped with their own. Key parts are made of metal for maximum safety, and the MiniSpin® plus is fast enough for molecular biology separations.

Supplier: JULABO

JULABO F Series chillers for basic laboratory cooling tasks. Ideal for replacing tap water. Provide recirculating fluid to applications at a consistent temperature and pressure. Compact design with easy to use digital interface including a timer. May be used with water or glycol/water mixtures. High quality construction with stainless steel components in combination with German engineering and quality for a long product lifetime.

Supplier: DWK Life Sciences (KIMBLE)

MIDI-VAP 4000 Systems feature a pre-programmed controller with automated shut-off. The Watlow SD digital controller is pre-programmed, with easy three-step setup, automatic shut-off, easy to read LED display and optional temperature programming.

Supplier: Nidec Shimpo America

The Series FGV-XY Force Gauges combine a rugged, ergonomic and compact design to provide a complete force testing instrument