4555 Results for: "Digital Thermometers&amp"

Supplier: VWR International

A compact general purpose centrifuge that is ideal for research and clinical applications.

Supplier: TWD Scientific

These high-quality digital pipettes feature built in error control and follow a comprehensive range of liquid handling protocols.

Supplier: Bioss

CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENP1), is an integral membrane glycoprotein that acts as an extracellular nucleotide-hydrolyzing enzyme. CD39 inhibits ADP-induced platelet aggregation by hydrolyzing ADP to AMP and ultimately generating adenosine. Intracellular CD39 undergoes glycosylation at 6 N-glycosylation sites and translocates to the membrane in order to be an active enzyme. CD39L1 is a 495 amino acid multi-pass membrane protein that requires calcium and magnesium cofactors to hydrolyze ATP and other nucleotides in the regulation of purigenic neurotransmission. CD39L1 is expressed in kidney, colon, heart, testis, pancreas, brain, prostate, skeletal muscle, small intestine and ovaries. There are two isoforms of CD39L1 that are produced as a result of alternative splicing events.

Supplier: Bioss

G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 128 (GPR128), a member of the secretin family of GCPRs with a GPS domain in its N-terminal domain, may mediate signaling processes to the interior of the cell via activation of G proteins. GPR128 represents an allopeptide which may be involved in T cell mediated transplant rejection as it is able to stimulate 2.102 T cells.

Supplier: Bioss

G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 128 (GPR128), a member of the secretin family of GCPRs with a GPS domain in its N-terminal domain, may mediate signaling processes to the interior of the cell via activation of G proteins. GPR128 represents an allopeptide which may be involved in T cell mediated transplant rejection as it is able to stimulate 2.102 T cells.

Supplier: Bioss

G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 128 (GPR128), a member of the secretin family of GCPRs with a GPS domain in its N-terminal domain, may mediate signaling processes to the interior of the cell via activation of G proteins. GPR128 represents an allopeptide which may be involved in T cell mediated transplant rejection as it is able to stimulate 2.102 T cells.

Supplier: Bioss

L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Supplier: Bioss

Cyclic AMP-dependent phosphodiesterase type D (PDE4D) family is comprise of 5 variants (PDE4D1, D2, D3, D4 and D5). One or more PDE4D subtype variants are ubiquitously present in all mammalian cells. In CNS all five PDE4D subtype variants are expressed in varying ratios and their activity is regulated in tandem with GPCRs stimulation. Peripheral tissues also exhibit differential expression of PDE4D variants. PDE4D1/D2 mRNA levels rise in response to an increase in cAMP. Short term regulation of PDE4D variants involved PKA, MAP kinases and Erk2 phosphorylation that results in rapid change in their enzymatic activities. Other regulatory mechanism involved protein protein interactions with cytoskeletal scaffolding proteins.

Supplier: Rockland Immunochemical

Glycerol-3-phosphate acyltransferase 1 (GPAT1), one of four known GPAT isoforms, is located on the mitochondrial outer membrane, allowing reciprocal regulation with carnitine palmitoyltransferase-1. It is thought to be critical for the development of hepatic steatosis; steatosis triggered by GPAT1 overexpression leads to hepatic and possibly peripheral insulin resistance. GPAT1 is transcriptionally upregulated by insulin and sterol regulatory element binding protein (SREBP-1) and downregulated by AMP-activated protein kinase. Mice deficient in GPAT1 exhibit decreased triacylglycerol (TAG) in cardiomyocytes even in high-fat diets, suggesting that GPAT1 contributes significantly to TAG accumulation in heart tissue during lipogenic or high fat diets. At least two isoforms of GPAT1 are known to exist.

Supplier: Nidec Shimpo America

The Series FGE-XY Digital Force Gauges combine a rugged, ergonomic and compact design with exceptional accuracy to provide a solid force testing instrument

Supplier: Antyila Scientific

Provides wide temperature range of -40 to 200 °C.

Supplier: Bioss

Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways. Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis. Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds, but does not require its catalytic activity, it may in part come from the mitochondrial form, which sensitizes the low-affinity Ca(2+) transporters, enhancing mitochondrial calcium uptake. Functions as tumor suppressor.

Supplier: Heathrow Scientific

Versatile shaker for a vast range of protocols. Create own matrix for vessels of all shapes and sizes with Hi-Lo platform and bungee cords.

Supplier: Ace Glass

Round-bottom flasks with four necks and [ST] outer joints

Supplier: Thermo Fisher Scientific

Stainless steel gable cover for 89L baths, 13491-010 and -014.

Supplier: Boekel

Boekel Scientific offers a wide range of quality Convection Ovens to meet your laboratory needs

Supplier: Thermo Fisher Scientific

Digital Waving Rotator is designed for ELISA, protein synthesis, gel staining and de-staining gels, antibody staining, and other time-sensitive applications.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of ESR1 mutations and its positive control. ESR1 (17 mutations) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 17 mutations in the ESR1 gene using the Ruby Chip. ESR1 is pivotal in mediating resistance to endocrine therapy in metastatic hormone-positive breast cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of NRAS mutations and its Positive Control. NRAS (G12, G12D) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the NRAS gene using the Ruby Chip. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific crystal flex probes and primers for the detection of GSTP1 methylation and its positive control. The GSTP1 methylation Crystal Digital PCR® assay is a 10X assay designed to detect and quantify methylation of the GSTP1 promoter using the ruby chip. The GSTP1 promoter is implicated on the GSTP1 epigenetic silencing and dysregulation of detoxification pathways contributing to tumor initiation, progression, and drug resistance.

Supplier: Germaine Laboratories

SafeCup™ lll Round Cups are a series of All-in-One (collection/testing/transport) qualitative tests for the detection of drugs of abuse in urine

Supplier: PEAK SCIENTIFIC MS

The PG14L gas generator from Peak Scientific is suitable for laboratory detectors requiring CO2 free gas such as FT-IR analysis.

Supplier: Heathrow Scientific

The MDX-series delivers digital accuracy and high-end features for specific applications. Brix and Refractive Index scales can be used in a wide variety of industries including: food and beverage, industrial, waste-water, aquatics, and many more.

Supplier: Thermo Fisher Scientific

Maximize valuable bench space with Thermo Scientific's compact and lightweight Dry Baths/Block Heaters, available with a variety of block size combinations for maximum sample versatility

Supplier: IKA Works

The space-saving high performers MICROSTAR series features new and easy-to-use stirrers convince with perfect basic functionalities, as well as with a compact design.

Supplier: Thermo Fisher Scientific

Increase your confidence in safety and accuracy with the sleek, low-profile RT2 hotplate. This unit offers precise digital control with 0.1 °C resolution with a PID microprocessor controller, and maximum temperature of 350 °C. The RT2 hotplate allows users to view both set point and actual top plate temperature at the same time, set a timer, and lock the keypad.

Supplier: DISCOVER ECHO INC.

This 'all-in-one' automated hybrid microscope can be used for upright and inverted observation methods.

Supplier: Sper Scientific

Rugged and waterproof, this refractometer is ideal for field use.

Supplier: IKA Works

The Hula Dancers are powerful orbital shakers.

Supplier: Beckman Coulter

Accessory item for use with the Airfuge Ultracentrifuge (BK340400). Provides advanced digital speed readout. Runs can be timed from 0-300 minutes in 5 minute increments.