91318 Results for: "DONEGAN+OPTICAL+COMPANY+INC&"
Drosophila melanogaster Dermcidin
Supplier: Anaspec Inc
Dermcidin-1L (DCD-1L) is a 48-amino acid antimicrobial peptide (AMP) with a Leu residue on the C-terminus. It is expressed in eccrine sweat glands, secreted into sweat, and transported to the epidermal surface. Unlike most AMPs, which are cationic, DCD has a net negative charge.
Sequence:SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL
MW:4818.5 Da
% peak area by HPLC:95
Storage condition:-20° C
Expand 1 Items
PhosphoWorks™ Fluorimetric Pyrophosphate Assay Kit, Blue Fluorescence, AAT Bioquest
Supplier: AAT BIOQUEST INC
Pyrophosphate (PPi) is produced by a number of biochemical reactions, such as ATP hydrolysis, DNA and RNA polymerizations, cyclic AMP formation by the enzyme adenylate cyclase and the enzymatic activation of fatty acids to form their coenzyme A esters.
Expand 1 Items
PhosphoWorks™ Fluorimetric Pyrophosphate Assay Kit, Enhanced Selectivity, AAT Bioquest
Supplier: AAT BIOQUEST INC
Pyrophosphate (PPi) is produced by a number of biochemical reactions, such as ATP hydrolysis, DNA and RNA polymerizations, cyclic AMP formation by the enzyme adenylate cyclase and the enzymatic activation of fatty acids to form their coenzyme A esters.
Expand 1 Items
Osmometer Calibration Standards
Supplier: FOUR E’S INDUSTRIAL GROUP INC.
Omolality calibration standards for clinical and research osmometers.
Expand 12 Items
CrossLab Pre-Optics Cone and Windows for ICP-OES, Agilent Technologies
Supplier: AGILENT TECHNOLOGIES, INC (CSD)
Pre-optics cones and axial/radial windows for Agilent ICP-OES.
Expand 6 Items
Glass Culture Cylinders and Cylinder Starter Set, Bioptechs Inc.®
Supplier: BIOPTECHS INC.
An assortment of borosilicate glass cylinders, all measuring 5 mm high, each with an optically flat polished end to eliminate the need for grease when plating cells.
Expand 9 Items
Human Recombinant cGAS (from E. coli)
Supplier: Cayman Chemical Company
Cyclic GMP-AMP (cGAMP) synthase (cGAS) (161-522) is a truncated form of cGAS (Item No. 22810) that contains the nucleotidyltransferase and Mab21 domains. cGAS is a nucleotidyltransferase located in the cytosol that acts as a cytosolic DNA sensor to detect foreign DNA from microbial pathogens as part of the innate immune response. Upon binding to cytosolic DNA, cGAS produces the cyclic dinucleotide second messenger cGAMP, which activates stimulator of interferon genes (STING), leading to activation of the type I interferon (IFN) pathway. In vitro, fibroblasts, macrophages, and dendritic cells isolated from cGAS knockout (cGAS-/-) mice do not produce type I IFNs following DNA transfection or DNA virus infection. Similarly, cells containing a frame-shift mutation in the cGAS locus fail to mount an immune response to HIV and other retroviruses. In vivo, cGAS-/- mice infected with herpes simplex virus 1 (HSV-1) have lower levels of IFN-α and IFN-β, shorter survival times, and higher post-mortem levels of HSV-1 in the brain.
Expand 1 Items
AMARA peptide
Supplier: Anaspec Inc
AMARA peptide is a minimal substrate for several members of the protein kinases family. It contains the phosphorylation site for AMP-activated Protein Kinase (AMPK). AMARA peptide may be employed in the applications to measure AMPK-related kinase activity.
Sequence:AMARAASAAALARRR
MW:1542.8 Da
% peak area by HPLC:95
Storage condition:-20° C
Expand 1 Items
Rectangular Absorption Cuvette, Firefly
Supplier: FIREFLYSCI, INC.
Cuvettes are made with optical glass ensuring high quality optical polishing with no defects.
Expand 1 Items
Tissue Culture Plates, Ultra Optically Clear, Azenta Life Sciences
Supplier: AZENTA US, INC
The main advantage of using ultra optically clear plates is in the optically ultra-clear base of the plate, which gives superior results by delivering low absorbance and high transmission, together with low background signals.
Expand 2 Items
System Accessories for Primaide™ HPLC System, Hitachi High-Tech America
Supplier: HITACHI HIGH-TECH AMERICA, INC.
PreparativeFlow Cell Assembly, Primaide 1430, Optical Pathlength 2Mm, Internal Volume 2.6Ul
Expand 12 Items
Motivational and Safety Banners, National Marker
Supplier: ACCUFORM MANUFACTURING, INC
Convey your company's commitment to safety and quality throughout your facility
Expand 22 Items
Accessories for FCS3® Closed Chamber System Starter Set, Bioptechs
Supplier: BIOPTECHS INC.
Replacement pressure plate, designed for use in the FCS3® Chamber to provide uniform pressure across the optical cavity.
Expand 1 Items
4000 Series Control Panels, Fixed Systems Gas Detection, GfG Instrumentation
Supplier: GFG INSTRUMENTATION, INC.
The GfG 4000 series is a compact and versatile control panel. Control panels may be configured with up to 16 channels of monitoring.
Expand 2 Items
Color Filter Paddles
Supplier: RAINBOW SYMPHONY INC SE
Lessons in Optics and Light in the Palm of Your Hand Colorfully illustrate additive and subtractive color mixing, color transmission, absorption and filtering of the different wavelengths of light with this set of primary and secondary color mixing paddles. You can also use the diffraction gratings in this set to view spectra from different light sources. Show students how a spectroscope, colored lights, and even polarized sunglasses work with the contents of this set.
Expand 1 Items
Miscellaneous Supplies for MP-AES, Agilent Technologies
Supplier: AGILENT TECHNOLOGIES, INC (CSD)
Supplies for MP-AES include Pre-optic window and disposable Onboard Argon bottle for plasma ignition.
Expand 1 Items
X-Rite Colorimeter Cell (Lightpaths: 2.5 to 100 mm), Type 96
Supplier: FIREFLYSCI, INC.
Colorimeter cell made from optical glass.
Expand 6 Items
qPCR Clear Adhesive Seals, Peelable
Supplier: AZENTA US, INC
The optically clear seal is specifically developed for optical applications, particularly qPCR.
Expand 3 Items
Fiber Optic Probes, Tips and Couplers for Cary UV Systems, Agilent Technologies
Supplier: AGILENT TECHNOLOGIES, INC (CSD)
Fiber optic probes, couplers, shields and tips for Versa/Dip probes used with Cary UV-Vis Systems.
Expand 2 Items
Histo-Vacuum, IMEB
Supplier: IMEB INC MS
Histo-Vacuum enables fast and easy cleanup for microtomes, cryostats, and IMEB's pathology bone band saw.
Expand 1 Items
Sealing Cap Strips, Flat, Crystal Clear, Azenta Life Sciences
Supplier: AZENTA US, INC
These strips of 8 flat crystal clear optical caps are designed for low volume applications such as low volume qPCR.
Expand 2 Items
Standard Spectrometer Cuvettes, with PTFE Lid, Firefly
Supplier: FIREFLYSCI, INC.
Cuvettes are made with different materials like optical glass, pyrex glass (10 mm only), UV quartz, IR quartz, sapphire (10 mm only) ensuring high quality optical polishing with no defects.
Expand 10 Items
Micro Fluorescence Cuvettes with PTFE Stopper, Type 30FL, FireflySci
Supplier: FIREFLYSCI, INC.
The Type 30FL cuvettes are made with optical glass, UV quartz, IR quartz with transmission values.
Expand 3 Items
Flame Photometric Detector (FPD) for GC, Agilent Technologies
Supplier: AGILENT TECHNOLOGIES, INC (CSD)
In 2005, Agilent released an improved FPD with a design based on a one-piece, deactivated transferline jet assembly and improved optics.
Expand 13 Items
BluePippin™ Gel Cassette Kit, Sage Science
Supplier: SAGE SCIENCE INC MS
Cassettes are disposable and pre-cast with agarose and running buffer. Samples are not optically detected.
Expand 1 Items
Anti-cGAS Mouse Monoclonal Antibody [clone: 5G10]
Supplier: Cayman Chemical Company
Cyclic GMP-AMP (cGAMP) synthase (cGAS; Item No. 22810) is a nucleotidyltransferase located in the cytosol that acts as a cytosolic DNA sensor to detect foreign DNA from microbial pathogens as part of the innate immune response. Upon binding to cytosolic DNA, cGAS produces the cyclic dinucleotide second messenger cGAMP, which activates stimulator of interferon genes (STING), leading to activation of the type I interferon (IFN) pathway. In vitro, fibroblasts, macrophages, and dendritic cells isolated from cGAS knockout (cGAS-/-) mice do not produce type I IFNs following DNA transfection or DNA virus infection.{39163} Similarly, cells containing a frame-shift mutation in the cGAS locus fail to mount an immune response to HIV and other retroviruses.{39164} In vivo, cGAS-/- mice infected with herpes simplex virus 1 (HSV-1) have lower levels of IFN-α and IFN-β, shorter survival times, and higher post-mortem levels of HSV-1 in the brain. Cayman’s cGAS Monoclonal Antibody (Clone 5G10) recognizes the full length human cGAS protein at ~59 kDa.
Expand 1 Items
Semi-Micro Black Cuvettes, with PTFE Stopper, Firefly
Supplier: FIREFLYSCI, INC.
Cuvettes are made with different materials like Optical Glass, UV quartz, IR quartz ensuring high quality optical polishing with no defects.
Expand 18 Items
Lighted Exit Sign, National Marker
Supplier: ACCUFORM MANUFACTURING, INC
Optically designed graphics and universal chevron arrows provide maximum directional information
Expand 1 Items
ML RR-S2 CDA (ammonium salt) ≥98%
Supplier: Cayman Chemical Company
ML RR-S2 CDA is a synthetic cyclic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds and is an activator of stimulator of interferon genes (STING).1 It contains mixed linkages (ML) with both 2'5' and 3'5' linkages, which leads to increased thermal stability of human STING in a differential scanning fluorimetry (DSF) assay. ML RR-S2 CDA increases type I interferon production by THP-1 human monocytes relative to unmodified cyclic di-AMP (CDA; Item No. 17753), indicating the ML enhances its action at human STING. It induces expression of IFN-β and the pro-inflammatory cytokines TNF-α, IL-6, and Mcp-1 in murine bone marrow macrophages (BMM) isolated from wild-type, but not STING-/-, mice. ML RR-S2 CDA also induces IFN-β expression in peripheral blood mononuclear cells (PBMCs) isolated from donors carrying STINGWT/WT, STINGWT/REF, and STINGWT/HAQ alleles. In vivo, ML RR-S2 CDA initiates tumor regression and prevents tumor growth upon tumor cell reimplantation in 4T1 breast and CT26 colon cancer mouse xenograft models.
Expand 2 Items
Disposable Cuvettes, Firefly
Supplier: FIREFLYSCI, INC.
Cuvettes are made with different materials like Acrylic, Polystyrene and UV Plastic ensuring high quality optical polishing with no defects.