30012 Results for: "Biosensis&pageNo=13&view=list"

Supplier: Bioss

Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner. TRIP13 is a transcription factor that interacts with the ligand binding domain of the thyroid receptor (TR) as well as a variety of target genes including human papilloma virus type 16 (HPV16) E1. Unlike most TRIP proteins which function only in the presence of hormones, TRIP13 does not require the presence of thyroid hormone to interact with TR. The association of TRIP13 with (HPV16) E1 suggests that TRIP13 may have tumor suppressor gene function. TRIP13 is a 432 amino acid protein with 2 different isoforms produced by alternative splicing.

Supplier: TrippNT

Heavy duty food grade high density polyethylene lab medical cart in many different colors with built-in tray top.

Supplier: Prosci

ST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates. At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion, and protein targeting.ST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates. At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion, and protein targeting (Samyn-Petit et al., 2000 [PubMed 10742600]).

Supplier: Prosci

APRIL Antibody: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for a proliferation-inducing ligand), TALL-2 (for TNF- and ApoL-related Leukocyte-expressed Ligand 2), and TRDL-1alpha (for TNF related death ligand 1alpha ) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kappa B, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.

Supplier: Prosci

CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

Supplier: BioFit

Eton Series chairs are comfortable and easy to adjust and clean, making them a favorite of today's technical, laboratory and healthcare professionals. A nimble trapezoid-shaped backrest promotes user range of motion and combines with a four-way contoured seat and ergonomic functionality to deliver long-term performance.

Supplier: Corning

Corning® Nu-Serum® growth media supplement provides a low-protein alternative to newborn calf, foetal bovine, and other sera routinely used for cell culture. The low-protein content facilitates protein purification, virus production, monoclonal antibody production and screening, and increases the frequency of successful transfection of cells.

Supplier: Prosci

The protein encoded by RGS13 is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown.

Supplier: Prosci

SLC22A13 is a member of the organic-cation transporter family. SLC22A13 is a transmembrane protein involved in the transport of small molecules. This protein can function to mediate urate uptake and is a high affinity nicotinate exchanger in the kidneys and the intestine.This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 4. The encoded protein is a transmembrane protein which is thought to transport small molecules and since this protein is conserved among several species, it is suggested to have a fundamental role in mammalian systems.

Supplier: VWR International

Microprocessor controlled
Synchronized and uniform mixing
Low-profile design
Best-in-Class, 5-year warranty
Available with a NIST Traceable, ISO/IEC 17025 Accredited Calibration Certificate from Troemner.

Supplier: DuPont

Tychem® 10000 exhibits excellent chemical barrier properties and offers an extremely durable fabric that is puncture- and tear-resistant.

Supplier: DuPont

Tychem® 10000 exhibits excellent chemical barrier properties and offers an extremely durable fabric that is puncture- and tear-resistant.

Supplier: Labconco

These enclosures provide practical, economical protection of operator and environment for applications involving biohazardous material and toxic particulates

Supplier: Siemens Healthineers

RAPIDPoint® 500 Blood Gas Analyzer from Siemens Healthcare Diagnostics delivers accurate, laboratory-quality test results for a comprehensive menu of critical care parameters in approximately 60 seconds, all from a single, whole-blood sample. The same RAPIDPoint® 500 Blood Gas Analyzer has been proven to address the need for accurate process analytics in all stages of development of bioprocessing applications.

Supplier: BD

PAXgene™ Blood DNA Tube is suitable for collection of whole blood for in vitro diagnostic (IVD) DNA testing.

Supplier: Brandtech

Oil-free, single-application vacuum systems offer incredibly quiet vacuum operation with electronic or flow control systems and integrated solvent recovery accessories

Supplier: OAKTON INSTRUMENTS MS

Designed for today's crowded laboratory benchtops.

Supplier: BioFit

Rexford Series Stools Ergonomic Adjustment Controls feature comfortable upholstered seats with highly resilient molded foam cushioning. Easy cleanability and a fingertip-controlled pneumatic height activator ring which enables adjustment from the entire seat perimeter make these Stool Ergonomic Adjustment Controls an ideal ergonomic solution for use in healthcare, laboratory, education and industrial environments.

Supplier: Rockland Immunochemical

The WAP four-disulfide core domain protein 2 (WFDC2), also known as epididymal protein 4, is a member of the WFDC domain family, a family of proteins that is characterized by the presence of Whey Acidic Protein (WAP) domain, and is highly expressed in the lung and salivary gland (1,2). Members of this family include SLPI and elafin, antiproteinases involved in the innate immune system (2). WFDC2 has been proposed to play a critical role in tumor formation and growth in ovarian cancer cells through the regulation of growth- and apoptosis-associated genes and may thus be a potential therapeutic target for epithelial ovarian cancer (3).

Supplier: Rockland Immunochemical

The closely related proteins KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK13 is expressed mainly in the brain, but is also observed in kidneys. KCNK13 has been suggested to be a candidate for the Cs+-permeable K+ channel activated by GABA(B) receptors.

Supplier: Ansell Healthcare

The lightest weight cut resistant and oil repellent glove providing enhanced worker comfort and safety, with strategically reinforced 'high wear' regions for extended-use life. These gloves are made up of Dyneema® diamond technology material.

Supplier: Contec

Lightweight, polyester disposable mops are excellent for applying disinfectants and for wet cleaning of vertical surfaces, ceilings, and walls in controlled environments. Ideal for reaching awkward corners and ceilings with a complete range of motion.

Supplier: BioFit

Eton Series chairs are comfortable and easy to adjust and clean, making them a favorite of today's technical, laboratory and healthcare professionals. This model is rated for use in ISO 6 cleanrooms. Its nimble trapezoid-shaped backrest promotes user range of motion and combines with a four-way contoured seat and ergonomic functionality to deliver long-term performance.

Supplier: Boster Biological Technology

Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 5(ABCG5) detection. Tested with WB in Human.

Supplier: NANOENTEK USA INC.

ADAM™ CellT is an automated cell counter that complies with the 21 CFR Part 11 which is a regulation on electronic records and signatures for use in cGMP facilities. Data cannot be modified by any user. Every action of users is recorded in an audit trail which includes the date, time, and specific details of the action.

Supplier: Scientific Industries

The Enviro-Genie® Benchtop Refrigerator Incubator features five capabilities in one unit: refrigeration, incubation, rotation, rocking, stirring.

Supplier: Bioss

PTPN13 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as I-kappa-B-alpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway.

Supplier: Prosci

The thyroid hormone (T3) receptors (TRs) are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. TRIP13 specifically interacts with the ligand binding domain of the TRs. It is a member of Trips (TR-interacting proteins) family. Nearly all of the Trips also show similar ligand-dependent interaction with the retinoid X receptor (RXR), but none interact with the glucocorticoid receptor under any conditions. Trips predict specific functional roles: one is an apparent human homolog of a yeast transcriptional coactivator, one is a new member of a class of nonhistone chromosomal proteins, and one contains a conserved domain associated with ubiquitination of specific target proteins.

Supplier: Bioss

PTPN13 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as I-kappa-B-alpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway.

Supplier: Greiner Bio-One

Urine tubes are designed for use as collection, transportation, or analysis vessels.