30012 Results for: "Biosensis&pageNo=13&view=list"

Supplier: Prosci

DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C. elegans. It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system. Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles. DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor.

Supplier: Bioss

Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner. TRIP13 is a transcription factor that interacts with the ligand binding domain of the thyroid receptor (TR) as well as a variety of target genes including human papilloma virus type 16 (HPV16) E1. Unlike most TRIP proteins which function only in the presence of hormones, TRIP13 does not require the presence of thyroid hormone to interact with TR. The association of TRIP13 with (HPV16) E1 suggests that TRIP13 may have tumor suppressor gene function. TRIP13 is a 432 amino acid protein with 2 different isoforms produced by alternative splicing.

Supplier: Rockland Immunochemical

YPEL2 (yippee-like 2) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL2 might be an important factor during the development and malignant transformation of tissues, most notably pancreatic and breast tumors.

Supplier: Electron Microscopy Sciences

Top of the Line Features a warning system deters accidental contact with hot surface.

Supplier: TrippNT

Food grade high density polyethylene lab cart in 12 colors with built-in tray, slides under counters, benchtops and fume hoods.

Supplier: Electron Microscopy Sciences

The Lab-Air System destroys odors and fumes and doesn't just mask them.

Supplier: Prosci

APRIL Antibody: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for a proliferation-inducing ligand), TALL-2 (for TNF- and ApoL-related Leukocyte-expressed Ligand 2), and TRDL-1 alpha (for TNF related death ligand 1 alpha ) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kappa B, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.

Supplier: BioFit

Bridgeport Series chairs boast a number of features and benefits that make them a popular choice for laboratory, healthcare, education, technical, industrial and office workspaces. The ergonomic design enhances user comfort and productivity when sitting for prolonged periods.

Supplier: Sartorius

The Sartolab^® P20 Pump is a specialized fluid feed pump optimized for use with Sartolab^® P20 pressure filtration devices. Sartorius recommends the Liquiport PML 16980 pump by KNF as the ideal companion for these filters, ensuring efficient sample processing. A key safety feature of this pump is the integrated pressure relief valve, which is pre-set to a maximum of 3.5 bar relative pressure. This valve serves as an essential protective mechanism, automatically activating to relieve pressure in the event of filter blockage that results in pressure buildup, thereby maintaining a secure and reliable operation.

Supplier: BIOASSAY SYSTEMS

For quantitative determination of uric acid and evaluation of drug effects on uric acid metabolism

Supplier: VWR International

Unit features red backlighting of the display so that answers may be read in poor lighting or darkness.

Supplier: DuPont

Tychem® 10000 exhibits excellent chemical barrier properties and offers an extremely durable fabric that is puncture- and tear-resistant.

Supplier: Sheldon Manufacturing

BACTRON chambers are total anaerobic process workstations. Samples can be prepared, cultured, and inspected in the oxygen-free chamber and standard incubator. Unlike anaerobic jars and bags, which unavoidably expose samples to oxygen, BACTRON units provide complete anaerobic environments for all your applications.

Supplier: BioFit

BioFit Elite Series seating, engineered for all-day comfort, is perfect for office and industrial workspaces. The ergonomic design enhances user comfort and productivity when sitting for prolonged periods.

Supplier: Rockland Immunochemical

The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.

Supplier: Brandtech

Dual application dry chemistry vacuum systems feature reliable and powerful pumps to provide whisper-quiet vacuum operation with integrated solvent recovery accessories

Supplier: Porex

Three-in-one filtration system filters, pipets, and stores samples

Supplier: Welch Vacuum

Fully integrated, oil-free vacuum pump and controller ideal for use with a rotary evaporator for stripping solvents with boiling points of 160°C (320°F) or higher, such as DMF, or low boiling point solvents such as methylene chloride

Supplier: Justrite

This Double Cylinder Hand Truck with Firewall provides safety when moving and storing of gas cylinders.

Supplier: Nordon/Hoshizaki Llc.

The Hoshizaki produces small cubelet nugget-style ice and water dispenser features either LED touch buttons (89166-544) or Opti-Serve touchless operation (76808-992). Both models feature a durable stainless steel exterior, advanced CleanCycle24™ design, and stainless steel auger with greaseless bearing.

Supplier: Greiner Bio-One

Ideal for use in glucose and lactate determinations, tubes contain an anticoagulant (potassium oxalate) and a stabilizer (sodium fluoride).

Supplier: Prosci

CHST13 catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. It transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. C4ST3 transfers sulfate to the C-4 hydroxyl of beta-1,4-linked GalNAc flanked by GlcUA residues in chondroitin (Kang et al., 2002 [PubMed 12080076]).

Supplier: SARSTEDT INC

The high quality of blood samples collected with the S-Monovette® blood collection system is due to the gentle aspiration technique. It has been proven to significantly reduce hemolysis rates compared to vacuum systems. As a result, erythrocytes remain intact and blood collection does not have to be repeated as often.

Supplier: BioVendor

Interleukin 1 receptor antagonist (IL-1RA) is a protein related to the IL-1 family based on its similarities in amino acid sequence to both IL-1 beta and IL-1 alpha.

Supplier: Prosci

THEM2 Antibody: THEM2, also known as ACOT13, belongs to the hotdog-fold superfamily and possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brain and has been shown to be co-localized with beta-tubulin on microtubules. THEM2 interacts with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids. At least two isoforms of THEM2 are known to exist.

Supplier: Prosci

APRIL Antibody: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for a proliferation-inducing ligand), TALL-2 (for TNF- and ApoL-related Leukocyte-expressed Ligand 2), and TRDL-1alpha (for TNF related death ligand 1alpha ) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kappa B, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.

Supplier: Bioss

Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner. TRIP13 is a transcription factor that interacts with the ligand binding domain of the thyroid receptor (TR) as well as a variety of target genes including human papilloma virus type 16 (HPV16) E1. Unlike most TRIP proteins which function only in the presence of hormones, TRIP13 does not require the presence of thyroid hormone to interact with TR. The association of TRIP13 with (HPV16) E1 suggests that TRIP13 may have tumor suppressor gene function. TRIP13 is a 432 amino acid protein with 2 different isoforms produced by alternative splicing.

Supplier: Genetex

Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO (see MIM 165370), RAC (see RAC1; MIM 602048), and CDC42 (MIM 116952). GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.[supplied by OMIM]

Supplier: BioFit

The AdapTable™ convertible bench table system provides the flexibility in demand for today’s learning environment. This 244 cm (8 ft.) long model can be configured as a table with a bench on one side, a bench with a back, or ganged with a second unit to form a wider table with bench seating on two sides.

Supplier: Peprotech

Recombinant Human IGF-I LR3, 9.1 kDa, single, non-glycosylated polypeptide chain containing 83 amino acid residues. Animal Free, Source: E.coli, Purity: > 98% by SDS-PAGE gel and HPLC analyses. Synonym: Long R3 IGF-I, Insulin-like Growth Factor-I, Pack Size: 1MG