2270 Results for: "BioVendor"

Supplier: BioVendor

N-terminal domain of alpha-dystroglycan is secreted into the cerebrospinal fluid. Its effect on the nervous system remains unclear. The complete dystroglycan complex is expressed in a variety of tissues and plays a role in processes such as laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.

Supplier: BioVendor

Total 490 AA. MW: 55.8 kDa (calculated). UniProtKB acc. No. Q9Y5X9 (Ser21–Pro500). N-terminal linker (2 extra AA), C-terminal linker (2 extra AA) and C-terminal His-tag (6 extra AA). Protein identity confirmed by LC-MS/MS.

Supplier: BioVendor

GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.

Supplier: BioVendor

Quality control test, Indirect ELISA – to determine titer of the antibody , SDS PAGE – to determine purity of the antibody, and BCA - to determine quantity of the antibody.

Supplier: BioVendor

Total 269 AA. MW: 30.2 kDa (calculated). UniProtKB acc.no. Q9NP85 (Val125-Leu383). N-terminal His-tag (10 extra AA). Protein identity confirmed by LC-MS/MS.

Supplier: BioVendor

Total 156 AA. MW: 17.8 kDa (calculated). UniProtKB acc.no. P48304. N-Terminal His-tag 12 AA

Supplier: BioVendor

Adiponectin has the potential to become a clinically relevant parameter to be measured routinely in subjects at risk for type 2 diabetes, atherosclerosis and the metabolic syndrome.

Supplier: BioVendor

Total 438 AA, M.w. 51.27kDa (calculated). The AA sequence (AA 1–427) is identical to Swiss-Prot-P10909 (AA 23–449, secreted Human Clusterin). C-terminal Flag-tag, 11 extra AA (highlighted).

Supplier: BioVendor

96 wells (1 kit) - ELISA is a competitive enzyme immunoassay for the quantitative measurement of anti-dsDNA.

Supplier: BioVendor

96 wells (1 kit) - ELISA is a sandwich enzyme immunoassay for the quantitative measurement of anti-SARS-CoV-2 nucleocapsid protein.

Supplier: BioVendor

Total 295 AA. MW: 31.3 kDa (calculated). UniProtKB acc.no. Q8TCT1. N-Terminal His-tag 14 AA (highlighted).

Supplier: BioVendor

The Cell-Clock Assay is a live-cell detection and measurement system that can be employed to monitor the four major phases of the mammalian cell cycle during in vitro culture

Supplier: BioVendor

Leucine-rich alpha-2-glycoprotein (LRG) is a secretory type 1 acute phase protein whose expression is upregulated by the mediators of acute-phase response. The level of LRG in the blood increases during microbial infections and cancer, presumably as a result of the liver’s response to pro-inflammatory cytokines . The function of LRG is unknown but it is proved that LRG is tightly binding to Cyt C. It is suggested that extracellular Cyt C that is released from the cell death by an acute inflammation could be trapped to form tight complex with LRG and be excluded from circulation. LRG secretion by human hepatoma cells is increased by treatment with a mixture of cytokines including IL-6, IL-1b, and TNFα that are known to induce acute-phase proteins.

Supplier: BioVendor

The mouse/rat obestatin EIA assay kit developed by our laboratory can be used for direct determination of serum obestatin level’s variation.

Supplier: BioVendor

Total 169 AA. MW: 19,2 kDa (calculated). UniProtKB acc.no. O95760. N-Terminal His-tag, 10 extra AA

Supplier: BioVendor

Total 102 AA. MW: 11.99 kDa (calculated). UniProtKB acc.no. P33763. N-Terminal His-tag, 10 extra AA

Supplier: BioVendor

Total 286 AA. MW: 33.3 kDa (calculated). N-terminal His-tag, 10exrea AA. The AA sequence is identical to UniProtKB/Swiss-Prot entry O76038.

Supplier: BioVendor

IL-8 (8 kDa, 72 amino acids) is a non-glycosylated protein and it is produced by the processing of a precursor protein of 99 amino acids.

Supplier: BioVendor

Interleukin-17 is involved in the regulation of hematopoiesis and its effects are dependent on the physiological/pathological status of the organism.

Supplier: BioVendor

Listeriolysin O (aka LLO) is a hemolysin produced by Listeria monocytogenes bacteria, the pathogen responsible for causing listeriosis. The toxin may be regarded as a virulence factor, since it is crucial for the virulence of L. monocytogenes. LLO is a single polypeptide protein encoded by the hlyA gene and composed of 529 residues. LLO is a thiol-activated cholesterol-dependent pore forming toxin protein; therefore, it is activated by reducing agents and inhibited by oxidizing agents. Still, LLO differs from other thiol-activated toxins, as its cytolytic activity is maximized at a pH of 5.5. Inside the acidic phagosomes (average pH ~ 5.9) of cells that have phagocytosed L. monocytogenes, LLO is selectively activated by maximizing activity at a pH of 5.5. Following the phagosome lysis by LLO, the bacterium breaks out into the cytosol, where it is able to grow intracellularly, and the toxin has reduced activity in the more basic cytosol. Thus, LLO permits L. monocytogenes to break out from the phagosomes into the cytosol without harming the plasma membrane of the infected cell, which allows the bacteria to live intracellularly, where they are sheltered from extracellular immune system factors such as the complement system and antibodies.

Supplier: BioVendor

IGFBP-2 is, after IGFBP-3, the second most frequent IGFBP in the human blood.

Supplier: BioVendor

In serum, FLC kappa exists predominantly as a monomer with a molecular weight of 22.5 kDa and FLC lambda as a dimer with a molecular weight of 45 kDa.

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sFRP-4 is a cystein-rich glycoprotein that belongs to the group of G protein-coupled receptor proteins. It is expressed in proliferative endometrium and several types of ovarian, endometrial and brest tumors. It is up-regulated in failing myocardium.

Supplier: BioVendor

Total 362 AA. MW: 40.68 kDa (calculated). UniProtKB acc.no. P27169 (Met1-Leu355). C-terminal His-tag (7 extra AA). Protein identity confirmed by LC-MS/MS.

Supplier: BioVendor

Gastrokine-2 is expressed in gastric mucosa.

Supplier: BioVendor

TPPP protein probably participates in the polymerization of tubulin into microtubules. The level of TPPP/p235 in cerebrospinal fluid is significantly higher in multiple sclerosis patients.

Supplier: BioVendor

96 wells (1 kit) - ELISA is a competitive enzyme immunoassay for the quantitative measurement of CTX-II.

Supplier: BioVendor

96 wells (1 kit) - ELISA is a sandwich enzyme immunoassay for the quantitative measurement of C-terminal telopeptides of Type l collagen.

Supplier: BioVendor

96 wells (1 kit) - ELISA is a competitive enzyme immunoassay for the quantitative measurement of AFABP4.

Supplier: BioVendor

Albumin is mostly a simple hydrophilic protein present in cells and body fluids.