2270 Results for: "BioVendor"

Supplier: BioVendor

Good for research into cardiovascular disease, Diabetology - Other Relevant Products, Energy metabolism and body weight regulation and Oncology. The immunization antigen (15.2 kDa) is a protein containing 135 AA of recombinant Human FABP5 and one extra AA, Nterminal methionine (highlighted).

Supplier: BioVendor

Total 392 AA. MW: 44.2 kDa (calculated). UniProtKB/Swiss-Prot Q9BY76 with C-Terminal Flag-tag, 11 extra AA.

Supplier: BioVendor

96 wells (1 kit) - ELISA is a sandwich enzyme immunoassay for the quantitative measurement of FGF-21.

Supplier: BioVendor

96 wells (1 kit) - ELISA is a competitive enzyme immunoassay for the quantitative measurement of IgE.

Supplier: BioVendor

A DNA sequence encoding the mature variant of ovVEGF-E isolate D1701 (Dehio et al., 1999; GenBank accession No. AF106020) was expressed in E. coli as a 132 amino acid residue fusion protein with an N-terminal His-tag sequence and a thrombin cleavage site. Recombinant VEGF-E homodimer was dimerized in vitro and has a predicted mass of approximately 35 kDa. Based on sequence similarity to VEGF-A, a gene encoding a VEGF homologue has recently been discovered in the genome of Orf virus (OV) (Lyttle et al., 1994). Different isolates of Orf virus show significant amino acid sequence similarity to VEGF-A and described as a viral virulence factor that appears to be derived from captured host genes. All eight cysteine residues of the central cysteine knot motif characteristic of members of the VEGF family are conserved among other residues in the VEGF-E proteins (Dehio et al., 1999; Wise et al., 1999). Alignment of all mammalian VEGF sequences indicated that VEGF-E is distinct from the previously described VEGFs but most closely related to VEGF-A. Like VEGF-A, VEGF-E was found to bind with high affinity to VEGF receptor-2 (KDR) resulting in receptor autophosphorylation, whilst in contrast to VEGF-A, VEGF-E can not bind to VEGF receptor-1 (Flt-1). Furthermore VEGF-E can also not bind to VEGF receptor-3 (FLT-4). Therefore VEGF-E is a potent angiogenic factor selectively binding to VEGF receptor –2/KDR.

Supplier: BioVendor

96 wells (1 kit) - ELISA is a sandwich enzyme immunoassay for the quantitative measurement of IGF-2.

Supplier: BioVendor

Quality control test, Indirect ELISA – to determine titer of the antibody , SDS PAGE – to determine purity of the antibody, and BCA - to determine quantity of the antibody.

Supplier: BioVendor

Quality control test, Indirect ELISA – to determine titer of the antibody , SDS PAGE – to determine purity of the antibody, and BCA - to determine quantity of the antibody.

Supplier: BioVendor

Quality control test, Indirect ELISA – to determine titer of the antibody , SDS PAGE – to determine purity of the antibody, and BCA - to determine quantity of the antibody.

Supplier: BioVendor

Quality control test, Indirect ELISA – to determine titer of the antibody , SDS PAGE – to determine purity of the antibody, and BCA - to determine quantity of the antibody.

Supplier: BioVendor

96 wells (1 kit) - ELISA is a sandwich enzyme immunoassay for the quantitative measurement of osteocalcin.

Supplier: BioVendor

Endo-RS* Endotoxin Recovery Kit, containing non-ionic surfactants such as Polysorbate 20, Polysorbate 80 or Octylphenol ethoxylates. Non-ionic surfactants are well known to cause Low Endotoxin Recovery(LER).

Supplier: BioVendor

Retinol binding protein (RBP) 4 is the only specific transport protein for vitamin A in the circulation whose function is to deliver vitamin to target tissues.

Supplier: BioVendor

Endothelial Leukocyte Adhesion Molecule-1 (ELAM-1, E-selectin) belongs to the selectin family of adhesion molecules.

Supplier: BioVendor

Secretoglobins are small disulfide linked dimeric proteins. Secretoglobin family 3A member 2 is highly expressed in lung.

Supplier: BioVendor

96 wells (1 kit) - ELISA is a competitive enzyme immunoassay for the quantitative measurement of lipocalin-2.

Supplier: BioVendor

IP-10 (Interferon-gamma inducible Protein 10kDa) also known as CXCL10, is secreted by several cell types in response to IFNg and LPS.

Supplier: BioVendor

Progranulin can restrain TNF mediated pro-inflammatory processes.

Supplier: BioVendor

Visceral adipose tissue – derived serpin A12 (vaspin), also named OL-64, an adipocytokine, is structurally a member of the serine protease family. Serpins are the most diverse family of protease inhibitors. Their typical structural feature is the core domain composed from 3 beta-sheets and 9 alpha-helixes. The inhibitory activity of vaspin has not been described up to now, but its reactive site loop is typical for this proteinase family. Human Vaspin protein is composed of 395 amino acids and has a molecular weight of approximately 45.2 kDa and predicted pI 9.26. The cDNA was first isolated from white adipose tissue of Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Vaspin mRNA expression is specific for visceral adipose tissues and it is also found circulating in the serum. The level of serum vaspin increased with age up to the peak of obesity, body weight and insulin resistance in OLETF rats and decreases with worsening of diabetes. Vaspin expression is missing in the diabetes-resistant lean rats, LETO, in comparison to OLEFT rats, animal model of metabolic syndrome. Expression was also absent in the subdermal, brown fatty tissue and other non-adipose tissues in OLEFT rats. These findings lead to the conclusion that the target tissue for insulin sensitising effect of vaspin is white adipose tissue. In humans, elevated serum concentration of vaspin is associated with obesity and impaired insulin sensitivity.

Supplier: BioVendor

CRP is an acute-phase protein, produced exclusively in the liver.

Supplier: BioVendor

Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation.

Supplier: BioVendor

Interferon-beta 1a Human Recombinant protein is a single, glycosylated polypeptide chain containing 166 amino acids and having a molecular mass of 22500 Dalton.

Supplier: BioVendor

Placental protein 13 (PP13, Galectin 13) is the member of the beta-galactoside binding S-type galectin superfamily, whose members are important in placenta implantation and remodelling of maternal arteries. PP13 binds to beta-galactoside residues of several proteins on the cell surface, cytoskeleton and extracellular matrix, thereby generating various responses such as immune responses and influencing other functions like apoptosis and molecular recognition. PP13, which is predominantly produced by placental tissue, possesses a conserved carbohydrate binding domain, to which two proteins Annexin-II and Actin-beta bind. These proteins are considered to play a key role in placentation and maternal artery remodelling respectively.

Supplier: BioVendor

Fas is a type I membrane protein that belongs to the TNF/nerve growth factor receptor family.

Supplier: BioVendor

Total 750 AA. MW: 82.4 kDa (calculated). UniProtKB acc.no. P49747. N-Terminal FLAG-tag, 13 extra AA (highlighted). Protein identity confirmed by LC-MS/MS.

Supplier: BioVendor

Human resistin contains 108 amino acids as a prepeptide, and its hydrophobic signal peptide is cleaved before its secretion.

Supplier: BioVendor

Trefoil factor 1 (TFF1, pS2) is a small secreted protein with molecular weight of 6.5 kDa (monomers, 14 kDa – dimers). It belongs to the TFF protein family that is characterized by a clover leaf–like disulphide structure named the TFF domain, which is created by 6 cysteines forming three intramolecular bonds. TFF1 contains one trefoil domain, but has a seventh cysteine in position 57 that is essential for formation of dimers. TFF1 exist as both monomers and dimers (homo- and heterodimers – with gastrokine 2). The most abundant expression of TFF1 is found in the GI tract (especially in stomach, colon and pancreas) where it is co-localised with mucins, usually with MUC5AC.

Supplier: BioVendor

Urocortin 2 (Ucn 2), also known as stresscopin-related peptide, is a novel predicted neuropeptide related to corticotropin-releasing factor (CRF).

Supplier: BioVendor

96 wells (1 kit) - ELISA is a sandwich enzyme immunoassay for the quantitative measurement of Anti-IgA isotype IgG.

Supplier: BioVendor

Fetuin B is a member of cystatin superfamily proteins, comprises two cystatin domains. It was found in secreted form in serum, it is expressed in liver, tongue and placenta. It regulates osteogenesis by inhibition effect on mineralization. It plays a role in oocyte maturation.