1809 Results for: "BMS-599626&amp"

Supplier: Adipogen

BMS-599626 is an orally bioavailable, highly selective and potent pan-HER kinase inhibitor. It inhibits HER1 and HER2 with IC(50) values of 20 and 30nM, respectively.

Supplier: Ambeed

BMS-599626 hydrochloride 98+%

Supplier: Ambeed

BMS-8 98%

Supplier: Adipogen

BMS-2 is a potent MET kinase inhibitor with an IC(50) value of 1.8nM. It also possesses potent inhibitory activity against Flt-3 and VEGFR-2 kinases, IC(50) values of 4nM and 27nM respectively.

Supplier: Adipogen

Kinases, such as LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2), have been identified as participating in signal pathways affecting actin dynamics by deactivating cofilin. Over expression of LMK1 has been found in invasive breast and prostate cancer cell lines and suppression of LIMK 2 expression has been found to limit migration of human fibrosarcoma cells. Thus, the inhibition of LIMK1 and/or LIMK2 enzymes have been suggested as targets for treating cancer, including reduction or prevention of metastasis. BMS-5 is a potent inhibitor of the LIM kinase. It has IC(50) values of 7nM and 8nM for LIMK1 and LIMK2 respectively. LIMK1/2 activity was measured via TCA precipitation assay using a biotinylated ADF (actin depolymization factor) as the protein substrate and the kinase domains of LIMK1 and LIMK2 as the enzyme sources in the presence of 1µM ATP.

Supplier: Adipogen

BMS-3 is a potent inhibitor of the LIM kinase. It has IC(50)'s of 5nM and 6nM for LIMK1 and LIMK2 respectively.

Supplier: Ambeed

BMS-754807 98+%

Supplier: ALADDIN SCIENTIFIC

AMP PNP ≥90% (by HPLC)

Supplier: Ambeed

BMS-303141 98%

Supplier: Ambeed

BMS-582949 ≥98%

Supplier: Adipogen

BMS-540215 is an ATP-competitive inhibitor of human VEGFR-2, with an IC(50) of 25nM and Ki of 26nM. BMS-540215 also showed good selectivity for FGFR-1 (IC(50) of 48nM), FGFR-2 (IC(50) of 125nM), and FGFR-3 (IC(50) of 68nM).

Supplier: Ambeed

BMS-777607 98%

Supplier: VWR

5% water has been added to maintain liquidity at room temperature.

Supplier: Ambeed

N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyramide, Purity: 98%, CAS Number: 1338247-35-0, Appearance: White to Beige Solid, Storage: Sealed in dry, Store in freezer, under -20 C, Size: 5mg

Supplier: Ambeed

N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)cyclopropanecarboxamide, Purity: 98%, CAS Number: 1338247-30-5, Appearance: White to off-white solid, Storage: Sealed in dry, Store in freezer, under -20 C, Size: 1mg

Supplier: Adipogen

BMS387032 is a novel cyclin-dependent kinase inhibitor, which exhibits potent and selective inhibitory activity against Cdk2, Cdk7, and Cdk9. It inhibits CDK2 with an IC(50) of 48nM and up to 20-fold selective over CDK1/CDK4. It also inhibits CDK7/9 with IC(50) values of 62nM and 4nM. It has little effect on CDK6.

Supplier: Ambeed

BMS-626529 98%

Supplier: AAT BIOQUEST INC

AMP-Fluorescein conjugate calibrator is desigend to use with AAT Bioquests' green fluorescent FAM-cAMP PDE IV substrate, a cAMP derivative that is a specific substrate for phosphodiesterase (PDE) IV.

Supplier: Ambeed

BMS-708163 98+%

Supplier: Cayman Chemical Company

Cyclic di-AMP (sodium salt), Purity: >/=98%, A second messenger produced by bacteria, but not by mammals, Synonyms: c-di-AMP, Cyclic di-Adenosine monophosphate, 3',5'-Cyclic diadenylic acid, Cyclic diadenylate, Size: 500ug

Supplier: Cayman Chemical Company

BMS 345541 (trifluoroacetate salt), Purity >/=98%, MF: C14H17N5.2CF3COOH, MW: 483.4, Synonyms: IKK Inhibitor III, N1-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine, trifluoroacetate salt, Formulation: crystalline, Storage: -20C, Size: 10mg

Supplier: Ambeed

BMS-986205 98+%

Supplier: Ambeed

BMS-863233 hydrochloride ≥98%

Supplier: Enzo Life Sciences

Adenosine 5'-monophosphate disodium salt (AMP disodium salt) ≥98% (by HPLC)

Supplier: Ambeed

Brivanib (BMS-540215) 96%

Supplier: Ambeed

N-(2-Methyl-5-((methylamino)methyl)phenyl)-4-((4-phenylquinazolin-2-yl)amino)benzamide, Purity: 98%, CAS Number: 1059734-66-5, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 50mg

Supplier: Ambeed

N-(4-((2-Amino-3-chloropyridin-4-yl)oxy)-3-fluorophenyl)-5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxamide, Purity: 98+%, CAS Number: 1174046-72-0, Appearance: White to off-white solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 5mg

Supplier: Ambeed

(R)-1-(4'-(3-Methyl-4-(((1-phenylethoxy)carbonyl)amino)isoxazol-5-yl)-[1,1'-biphenyl]-4-yl)cyclopropane-1-carboxylic acid, Purity: 97%, CAS Number: 1257213-50-5, Appearance: White to Yellow Solid, Storage: Sealed in dry, Room Temperature, Size: 10mg

Supplier: Thermo Scientific Chemicals

100ML

Supplier: Spectrum Chemical Mfg. Corp.

2-Amino-2-methyl-1-propanol, or aminomethyl propanol is a colorless, viscous liquid that functions as a pH adjuster. It is also used as an intermediate in drug synthetic schemes.