232556 Results for: "Apollo Scientific Ltd"

Supplier: Prosci

NMDA receptors are members of the ionotropic class of glutamate receptors, which also includes Kainate and AMPA receptors. NMDA receptors consist of NR1 subunits combined with one or more NR2 (A-D) or NR3 (A-B) subunits. The ligand-gated channel is permeable to cations including Ca2+, and at resting membrane potentials NMDA receptors are inactive due to a voltage-dependent blockade of the channel pore by Mg2+. NMDA receptor activation, which requires binding of glutamate and glycine, leads to an influx of Ca2+ into the postsynaptic region where it activates several signaling cascades, including pathways leading to the induction of long-term potentiation (LTP) and depression (LTD). NMDA receptors have a critical role in excitatory synaptic transmission and plasticity in the CNS. They govern a range of physiological conditions including neurological disorders caused by excitotoxic neuronal injury, psychiatric disorders and neuropathic pain syndromes.

Supplier: SAMPLING SYSTEMS LTD

PS or HDPE, sterile or non sterile. These disposable micro spatulas are ideal for sampling small volumes.

Supplier: SAMPLING SYSTEMS LTD

Disposable samplers for taking a single sample from free flowing powder and granules.

Supplier: PALBAM 2008 AC LTD TE

Palbam Class is a world-renowned cleanroom gowning design and furniture supplier. The extensive range of gownroom products designed and manufactured by Palbam Class is second to none.

Supplier: SAMPLING SYSTEMS LTD

Stainless jugs are perfect for use in laboratory and production applications.

Supplier: SAMPLING SYSTEMS LTD

This stainless steel sieving tool is ideal for pushing powders through mesh screens. The heavy base can be used to help break down small lumps and agglomerates.

Supplier: SAMPLING SYSTEMS LTD

These paddles are ideal for use when producing liquids and suspensions. Stirrers are made from 316 stainless steel.

Supplier: SAMPLING SYSTEMS LTD

GMP jugs in 316L stainless steel for easy pouring.

Supplier: SAMPLING SYSTEMS LTD

Brushes with nylon bristles in a twisted stainless steel wire frame and aluminium handle. Ideal for cleaning both stainless steel and plastic samplers.

Supplier: SAMPLING SYSTEMS LTD

Designed to collect single large volume sample from a single known point of free flowing powders from drums, kegs, and most containers.

Supplier: PALBAM 2008 AC LTD TE

Palbam Class is a world-renowned cleanroom gowning design and furniture supplier. The extensive range of gownroom products designed and manufactured by Palbam Class is second to none.

Supplier: PALBAM 2008 AC LTD TE

Palbam Class is a world-renowned cleanroom gowning design and furniture supplier. The
extensive range of gownroom products designed and manufactured by Palbam Class is second to none.

Supplier: SAMPLING SYSTEMS LTD

Straight tweezers make light work of handling intricate items such as tissues and vials.

Supplier: SAMPLING SYSTEMS LTD

The polypropylene screw top containers are ideal for multiple applications including production, warehouse, sampling, and general laboratory work.

Supplier: SAMPLING SYSTEMS LTD

These stainless steel pots with lids are general purpose containers that are ideal for use with powders and liquids. The lid is a simple drop on design.

Supplier: SAMPLING SYSTEMS LTD

The stainless steel liquid dip sampler is used to collect a wide variety of liquid samples from the surface.

Supplier: SAMPLING SYSTEMS LTD

U-D Master is designed for sampling free flowing powders. By simply changing the sample insert cells, different volumes can be sampled.

Supplier: SAMPLING SYSTEMS LTD

These measuring scoops made from high quality 316 stainless steel are ideal for scooping out fixed volumes of powder.

Supplier: SAMPLING SYSTEMS LTD

These stainless steel containers are made from high-quality 316L stainless steel and are ideal for almost all aplications, including GMP use.

Supplier: SAMPLING SYSTEMS LTD

These stainless steel micro spatulas are ideal for working with small amounts of powder. It has a flat blade that can be used to lift or decant small amounts of powder.

Supplier: SAMPLING SYSTEMS LTD

Designed for heavy-duty use in pharmaceutical, chemical, and food facilities.

Supplier: SAMPLING SYSTEMS LTD

The SteriWare range of greduated beakers are ideal for use in the production of drugs, chemicals and cosmetics.

Supplier: SAMPLING SYSTEMS LTD

Mixing bowls, made of HDPE, ideal for laboratories, production and small scale work.

Supplier: SAMPLING SYSTEMS LTD

These ladles made from hygienic stainless steel are ideal for sampling liquid products. The ladles have a crevice free construction so that they can be easily cleaned between batches.

Supplier: SAMPLING SYSTEMS LTD

The LiquiDip samplers are designed for taking cross sectional or point samples of liquids. The valve on the base of the sampler automatically closes when it is pushed against the container.

Supplier: SAMPLING SYSTEMS LTD

The square scoops made from 316 stainless steel are ideal for dispensing and sampling powders and granules along flat surfaces.

Supplier: SAMPLING SYSTEMS LTD

Our O-ring Seals are sized to suit our range of Mini-Drums. These seals when used with toggle clamps will help seal the containers.

Supplier: Bioss

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).

Supplier: Biosensis

BDNF belongs to the neurotrophin family and regulates the survival and differentiation of neurons during development. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain.FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family.

Supplier: Biosensis

BDNF belongs to the neurotrophin family and promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family.