4830 Results for: "Adipogen"

Supplier: Adipogen

NLRP3/NALP3 inflammasome activator. Specially crystallized and tested for biological activity.
Stimulates the caspase-1 activating NLRP3/NALP3 inflammasome, resulting in the production of active IL-1beta and IL-18.

Supplier: Adipogen

Anticancer compound. Apoptosis inducer. Anti-angiogenic. Anti-inflammatory. Antibacterial. Phytotoxic.

Supplier: Adipogen

Selective inhibitor of 5-lipoxygenase. Apoptosis and cell cycle arrest inducer. Anticancer compound. Inhibits ERK1/2, JNK, and NF-kappaB activation and expression of Raf-1 and Ras. Anti-proliferative compound. Anti-inflammatory and immunosuppressive. Anti-apoptotic compound in hepatocytes. Antioxidant. Antidiabetic. Enhances hepatic and plasma glucose metabolism and increases insulin secretion in type 2 diabetic mice. Inhibits angiogenesis by blocking STAT3 and VEGF expression. Neuroprotective. PI3K Class I, MKK3/6 and MKK4 inhibitor. Shown to inhibit osteoporosis dually through transcriptional suppression and actin rearrangement.

Supplier: Adipogen

Mammalian antibacterial metabolite. Inhibitor of isocitrate lyase, the key enzyme of the glyoxylate cycle, essential for bacterial growth. Antimicrobial. Antibacterial. Inhibits the growth of bacteria expressing isocitrate lyase. Phosphofructokinase (PFKII) inhibitor. Suppresses glycolysis by decreasing the level of fructose 2,6-bisphosphate, resulting in decreased visceral fat. Might be involved in the regulation of metabolism. One of the most highly induced metabolites in activated macrophages. Exerts anti-inflammatory effects in vitro and in vivo. Regulates succinate levels by inhibiting succinate dehydrogenase (SDH). Regulates mitochondrial respiration and cytokine production. Might induce inflammasome activation and consequently IL-1beta secretion by generating ROS.

Supplier: Adipogen

Benzoquinone ansamycin antibiotic

Supplier: Adipogen

Potent ATPase inhibitor. Potent competitive inhibitor of reverse transcriptase. Shows anti-HIV activity. Anticancer compound. Protein kinase C (PKC) inhibitor. Potent inhibitor of melanoma heparanase and tumor cell metastasis. Non-specific growth factors inhibitor (including PDGF, EGF, aFGF and bFGF). TGF-beta1 inhibitor. Topoisomerase I and II inhibitor. Interleukin-1 (IL-1) inhibitor. Interleukin-4 (IL-4) inhibitor. G protein inhibitor. P2X and P2Y purinergic receptor antagonist. Antiangiogenic. Potent VEGF inhibitor. Telomerase inhibitor. Shows adjuvant properties. Regulates ryanodine receptor. Direct adenylyl cyclase inhibitor. Protein synthesis inhibitor. SIRT1 (sirtuin 1) and SIRT5 (sirtuin 5) inhibitor. Immunosuppressive. Antifibrotic agent. Antiparasitic. Antiprotozoal. Athelmintic. Cullin-RING E3 ubiquitin ligase inhibitor.

Supplier: Adipogen

Antibiotic

Supplier: Adipogen

Free radical scavenger and antioxidant. Potential compound to neutralize radioactive and toxic wastes and "heal" soils. Chelates and binds scores of minerals into a bioavailable form used by cells. Shown to incorporate into bone and cartilage of rats. Antibacterial. Antifungal. beta-Hexosaminidase release inhibitor. Anti-inflammatory. Tau fibrils aggregation inhibitor (Alzheimers Disease). Antiseptic. Interrupts the dimer formation of Abeta(17-42) peptides.

Supplier: Adipogen

Fluorescent dye which is widely used for staining polymer particles, but also organelles or materials used in medicine.

Supplier: Adipogen

Alkaloid used to study its effects as an antagonist of adrenergic and nicotinic receptors.

Supplier: Adipogen

N4-Acetylsulfamethoxazole is a metabolite of the sulfonamide bacteriostatic antibiotic sulfamethoxazole.

Supplier: Adipogen

Fluorescent reagents (probe, stain, label) with reactive functional group for chromatography or spectroscopy. Derivatization agent. Used for membrane research, luminescent detection, molecular biology, protein modifications, protein structural analysis and proteomics. Carbohydrate labels for chromatography.

Supplier: Adipogen

Widely used fluorophore well-known for preparing fluorogenic 7-Amido-4-methylcoumarin (AMC) substrates for cystine aminopeptidase and other hydrolases. Used as reference compound in enzyme assays.

Supplier: Adipogen

A synthetic intermediate.

Supplier: Adipogen

Derivatizing reagent with strong fluorescence.

Supplier: Adipogen

Fluorination reagent.

Supplier: Adipogen

A neonicotinoid insecticide. Compound can be used as analytical reference material.

Supplier: Adipogen

Control for H2S2 and hydrogen polysulfides probes.

Supplier: Adipogen

N-Decanoyl-DL-homoserine lactone (N-C10-HSL) is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.

Supplier: Adipogen

Primarily used as a histological dye to detect indoles. Reagent for the determination of aromatic amines. It is used for the rapid identification of bacteria containing apotryptophanase and tryptophanase enzyme systems. It is also particularly useful for localization of proanthocyanidins compounds in plants, resulting in a blue staining. Has been developed for flavanoids in beer and is used in forensics.

Supplier: Adipogen

Building block for synthesis.

Supplier: Adipogen

Amidoxime fungicide used in agroculture. Active against powdery mildew of various crops in pre and post infection treatment. Has a long lasting translaminar and vapor phase activity. The mode of action is not know and it is considered different from that of other existing fungicides. It has favorable toxicological, ecotoxicological and environmental profiles. Compound can be used as analytical reference material.

Supplier: Adipogen

Pentoxifylline (PTX) metabolite. Can be used as reference material. Showed platelet aggregation in whole blood in vitro. Shown to be more effective than PTX in protecting WC/1 murine fibrosarcoma cells from TNF-alpha cytotoxicity and in inhibiting neutrophil superoxide anion production, degranulation (lactoferrin release) and surface expression of the beta-2 integrin CD11b/CD18.

Supplier: Adipogen

Metal-organic frameworks (MOFs).

Supplier: Adipogen

Cyanides/Nitriles. Organic building block for synthesis.

Supplier: Adipogen

Choline fungicide that inhibits spore germination of fungal spores by preventing the formation of appressoria that are necessary for infection of host plants. Possible secondary mode of action is stimulating the expression of host defence genes. Controls powdery mildew on cereals and grapevines. Compound can be used as analytical reference material.

Supplier: Adipogen

A major beta-oxidation metabolite of valproic acid (VPA). Exhibits anticonvulsive potency similar to VPA and may be at least partially responsible for its neurological activity. Compound can be used as analytical reference material.

Supplier: Adipogen

Hydroxycinnamic acid. Secondary plant metabolite of the phenylpropanoid pathway. It is a precursor in the biosynthesis of sinapic acid. Formed from ferulic acid by the action of the specific enzyme ferulate 5-hydroxylase (F5H).

Supplier: Adipogen

Fluorescent dye.

Supplier: Adipogen

Analytical/Chromatography reagent. Ion sensor compound. Additive for ISE.