131793 Results for: "6-Bromo-4,4-dimethyl-1,4-dihydrobenzo[d][1,3]oxazin-2-one&amp"

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CRYOS BIOBANKING TUBE BROWN 1000UL CS960

Supplier: Greiner Bio-One

CRYOS BIOBANKING TUBE BROWN 1000UL CS960

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CELLVIEW SLIDE 10WELL ADVANCED TC CS20

Supplier: Greiner Bio-One

CELLVIEW SLIDE 10WELL ADVANCED TC CS20

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VACUETTE VISIO + NEEDL 22GX1.25 ST PK100

Supplier: Greiner Bio-One

VACUETTE VISIO + NEEDL 22GX1.25 ST PK100

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Anti-SAA Mouse Monoclonal Antibody [clone: 607]

Supplier: Genetex

The serum amyloid A family comprises a number of differentially expressed apolipoproteins, acute-phase SAA1 and SAA2, the former being the major component in plasma and constitutive SAAs. Although the liver is the primary site of synthesis of both SAA types extrahepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed its importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations; SAA rises earlier and more sharply than CRP. Recently, a broader view of SAA expression and function has been emerging. Expression studies show production of SAA proteins in histologically normal, atherosclerotic, Alzheimer, inflammatory, and tumour tissues. SAA has been found to have binding sites for high density lipoproteins, calcium, laminin, and heparin/heparin sulphate. Also adhesion motifs were identified and new functions affecting cell adhesion, migration, proliferation, and aggregation were discovered. These findings emphasize the importance of SAA in various physiological and pathological processes including inflammation, atherosclerosis, thrombosis, AA-amyloidosis, rheumatoid arthritis, and neoplasia. SAA has also a number of immunomodulatory roles, it can induce chemotaxis and adhesion molecule expression, has cytokine-like properties and can promote the upregulation of metalloproteinases. It enhances the binding of high density lipoprotein to macrophages and thus helps in the delivery of lipids to sites of injury for use in tissue repair, it is thus thought to be an integral part of the disease process.

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Anti-BDNF Mouse Monoclonal Antibody [clone: 4C8]

Supplier: Biosensis

BDNF belongs to the neurotrophin family and promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family. Antibody reacts with human, mouse, rat, guinea pig BDNF. Expected to detect BDNF from other species due to sequence homology.

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TUBE K2EDTA MINICOLLECT 0.25/0.5ML PK500

Supplier: Greiner Bio-One

TUBE K2EDTA MINICOLLECT 0.25/0.5ML PK500

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BIOBANKING TUBE CRYO.S W/PINK CAP 300UL

Supplier: Greiner Bio-One

BIOBANKING TUBE CRYO.S W/PINK CAP 300UL

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BIOBANKING TUBE CRYO.S W/BK CAP 300UL

Supplier: Greiner Bio-One

BIOBANKING TUBE CRYO.S W/BK CAP 300UL

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6733-2 WIRE TEST LEAD RED 50FT

Supplier: NEWARK IN ONE MS

6733-2 WIRE TEST LEAD RED 50FT

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Laboratory Glassware Washers, PLW 8615, Miele

Supplier: Miele

The PLW 8615 laboratory washer can accommodate 216 laboratory flasks, 588 vials, or 294 pipettes. The large glassware washer is flexible and simple to use, it has modular load carriers and SimpleLoad system. This efficient unit has a single door, 900 mm wide, a usable capacity of 351 litres. PLW 8615 provides reliable results, high pump performance with a variable-speed pump and features spray arm monitoring and a conductivity meter.