131786 Results for: "6-Bromo-4,4-dimethyl-1,4-dihydrobenzo[d][1,3]oxazin-2-one&amp"

Supplier: Promega Corporation

These seven reporter vectors contain response elements (ARE, p53 RE, AT6 RE, MRE, HSE, HRE and XRE) that are important in various stress signaling pathways, the firefly luciferase gene and hygromycin resistance for selection in cells.

Supplier: Prosci

ADAM10 Antibody: Proinflammatory cytokine tumor necrosis factor-alpha (TNF-alpha ) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-alpha , notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-alpha , notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues.

Supplier: G-Biosciences

G-Biosciences' FOCUS™ Protein Alkylation Kit contains an ultra pure, proteomic grade iodoacetamide reagent for blocking thiols by alkylation in order to prevent the reoxidation of proteins

Supplier: Binder

The MFK series of dynamic climate chambers has been specially developed as precision heating and cooling chambers for complex standards-based climatic testing.

Supplier: NABERTHERM INC.

Due to their solid construction and compact stand-alone design, these high-temperature furnaces are perfect for processes in the laboratory where the highest precision is needed.

Supplier: SenseAnywhere

The Hermetically Sealed Pt100 Probe, with a digital SenseAnywhere Bus and PFA seal, specializes in extreme temperature measurements in liquids, from –90 to +250 ˚C. Chemical-resistant and waterproof, it's perfect for harsh environments. It requires calibration only for the probe, with easy monitoring via the SenseAnywhere Portal.

Supplier: Cytiva

903 sample collection card with four sample spots.

Supplier: Thermo Fisher Scientific

Get premium performance and flexibility with the Orion™ Versa Star Pro™ Meter with pH/ISE, Conductivity and RDO/DO Modules to measure up to four channels at once.

Supplier: Prosci

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by beta-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct subunits GluR1-4 and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR1 subunit is widely expressed throughout the nervous system. GluR1 is also potentiated by phosphorylation at Ser831. In addition, phosphorylation of this site has been linked to synaptic plasticity as well and learning and memory.

Supplier: Labconco

FreeZone® 18 Liter Console Freeze Dryers are designed for lyophilizing moderate to large sample loads or numerous small container batches.

Supplier: Labconco

FreeZone 12 Liter Console Freeze Dryers with Stoppering Tray Dryers are designed for lyophilizing moderate to large loads and stoppering vials or serum bottles under vacuum. Collectors are available to -50° C or -84° C.

Supplier: Thermo Fisher Scientific

The Thermo Scientific™ IntelliStack™ CO₂ Incubator shaker is a versatile laboratory instrument used for incubating and agitating samples simultaneously. It combines the functions of an incubator and shaker, providing a controlled environment for cell culture, microbial growth, and various other applications. With adjustable temperature, speed, and CO₂ concentration settings, it offers precise control over experimental conditions. A large, easy-to-use 10" color touchscreen display with alarms, alerts, real-time monitoring of key parameters, and data logging with export via USB or Ethernet allows for easy operation.

Supplier: Thermo Fisher Scientific

The Barnstead GenPure xCAD Plus water purification systems provides up to 200L/day of Type 1, ultrapure (18.2 megohm) water from pre-treated feed water

Supplier: VWR International

VWR® Advanced Mini Dry Block Heaters and Mini Dry Block Heaters with Heated Lid are ideal for a variety of applications that require accurate and repeatable results such as LAMP assays, immunoassays, enzyme reactions, and denaturations.

Supplier: Thermo Fisher Scientific

Accurately measure pH, ion concentration, conductivity, dissolved oxygen and temperature with the Orion™ Star™ A329 pH/ISE/Conductivity/RDO/DO Portable Meter.

Supplier: Promega Corporation

Ribonuclease inhibitors with broad-spectrum RNase inhibitory properties. Recombinant and native available. Plus version protects RNA before, during and after heating.

Supplier: NEWARK ELEMENT 14 MS

RELAY SOLID STATE PANEL SPST-NO 3A 48VDC

Supplier: NEWARK ELEMENT 14 MS

CONTROLLER PXU21A20 PXU 1/16N 2XINPUTS

Supplier: Labconco

These portable systems provide user protection by keeping powders and particulates contained during weighing procedures

Supplier: Enzo Life Sciences

Endothelins are vasoactive peptides that exist in three forms (ET-1, ET-2, and ET-3), and function in the maintenance of vascular tone via two identified seven transmembrane-spanning domain-containing G protein-coupled receptors (GPCR), endothelin A (ETA) and endothelin B (ETB). The human ETA receptor is primarily expressed in vascular smooth muscle cells, including those of the heart (also in myocytes), lung, and brain, and its stimulation generally results in vasoconstriction. Activation of ETA receptors can be stimulated by binding of ET-1 and ET-2, but not ET-3. triggering the release of vasorelaxive factors such as nitric oxide (NO) and prostanoids from endothelial cells. Human ETB receptors are primarily expressed in endothelial cells lining the vessel walls of the lungs, heart, and brain, and in contrast to ETA receptors, stimulation generally results in transient vasodilation. Activation of ETB receptors can be stimulated by binding of all three endothelins, triggering the release of vasorelaxive factors such as nitric oxide (NO) and prostanoids from endothelial cells. Both ETA and ETB receptors signal primarily via coupling to Gq/11 alpha subunits, although Gi/o and Gs coupling are also established mechanisms of endothelin signaling, resulting in stimulation of phospholipases C, A2, and D.

Supplier: Labconco

FreeZone® 6 Liter Console Freeze Dryers are designed for lyophilizing moderate to large sample loads or numerous small container batches. Collectors are available to -50°C or -84°C.

Supplier: Promega Corporation

Ribonuclease inhibitors with broad-spectrum RNase inhibitory properties. Recombinant and native available. Plus version protects RNA before, during and after heating.

Supplier: Promega Corporation

pGL4.44[luc2P/AP1 RE/Hygro], pGL4.49[luc2P/TCF-LEF RE/Hygro], pGL4.29[luc2P/CRE/Hygro], pGL4.30[luc2P/NFAT-RE/Hygro], pGL4.32[luc2P/NF-κB-RE/Hygro], pGL4.33[luc2P/SRE/Hygro] and pGL4.34[luc2P/SRF-RE/Hygro] Vectors can explore various signaling pathways.

Supplier: Corning

Corning® Synthegel™ 3D matrices are chemically defined peptides that self assemble into nanofibers which crosslink to form tuneable hydrogels. These hydrogels provide a robust and reproducible microenvironment for 3D culture of physiological spheroids and hiPS cells. The Synthegel™ matrix kits provide negligible variability and a more controlled substrate for in vivo-like 3D cell culture. Such a platform is needed for cancer research, stem cell research, and drug screening in a 3D format.

Supplier: BRAINTREE SCIENTIFIC INC MS

Multi-syringe programmable syringe pump built for automation - Operates stand-alone or from a computer. Infusion and withdrawal, set a single pumping rate, set a dispensing volume, or program up to 41 pumping phases that change pumping rates, set dispensing volumes, insert pauses, control and respond to external signals, sound the buzzer.

Supplier: NEWARK ELEMENT 14 MS

SCREWDRIVER WELLER XCELITE PHILLIPS 76MM

Supplier: NEWARK ELEMENT 14 MS

DEVICE MULTIFUNCTION I/O USB-6002 50KSPS

Supplier: NEWARK ELEMENT 14 MS

MULTIMETER UTILITY DIGITAL 6000 COUNT

Supplier: NEWARK ELEMENT 14 MS

CONTROLLER TEMPERATURE 1/16IN 0-50DEG C

Supplier: NEWARK ELEMENT 14 MS

NOZZLE CONVECTION TOOL 24.5MMX18.5MM